Results 81 to 90 of about 82,160 (288)

Characterization of ROP GTPase-activated Arabidopsis receptor-like cytoplasmic kinases (RLCK class VI_A) [PDF]

open access: yes, 2011
Plants have to respond and adapt to a variety of continuously changing environmental factors in order to establish an appropriate developmental strategy to ensure survival. There are ample data showing that protein phosphorylation/dephosphorylation plays
Jurca Elena Manuela
core  

Hyaluronan-CD44 interaction promotes microRNA signaling and RhoGTPase activation leading to tumor progression. [PDF]

open access: yes, 2012
A hallmark of all solid tumor malignancies is the ability to invade the surrounding tissue and/or metastasize to distant sites. Tumors cells have altered signaling pathways which that to cytoskeleton activation and migration.
Bourguignon, Lilly YW
core   +1 more source

A truncation mutant of adenomatous polyposis coli impairs apical cell extrusion through elevated epithelial tissue tension

open access: yesCytoskeleton, EarlyView.
Abstract Tissue tension encompasses the mechanical forces exerted on solid tissues within animal bodies, originating from various sources such as cellular contractility, interactions with neighboring cells and the extracellular matrix. Emerging evidence indicates that an imbalance in such forces can influence structural organization, homeostasis, and ...
Wan J. Gan   +7 more
wiley   +1 more source

Function and regulation of Rnd proteins in cortical projection neuron migration

open access: yesFrontiers in Neuroscience, 2015
The mammalian cerebral cortex contains a high variety of neuronal subtypes that acquire precise spatial locations and form long or short-range connections to establish functional neuronal circuits.
Roberta eAzzarelli   +3 more
doaj   +1 more source

Interaction Between Actin and Microtubules During Plant Development

open access: yesCytoskeleton, EarlyView.
ABSTRACT The dynamic interaction between actin filaments (AFs) and microtubules (MTs) plays a crucial role in regulating key developmental and physiological processes in plant cells, particularly in the formation of specialized cell types with distinct shapes and functions, such as pollen tubes, trichomes, and leaf epidermal cells.
Zining Wu   +3 more
wiley   +1 more source

Loss of RhoB expression enhances the myelodysplastic phenotype of mammalian diaphanous-related Formin mDia1 knockout mice. [PDF]

open access: yesPLoS ONE, 2009
Myelodysplastic syndrome (MDS) is characterized by ineffective hematopoiesis and hyperplastic bone marrow. Complete loss or interstitial deletions of the long arm of chromosome 5 occur frequently in MDS.
Aaron D DeWard   +4 more
doaj   +1 more source

IAPs as E3 ligases of Rac1 : shaping the move [PDF]

open access: yes, 2012
Inhibitors of Apoptosis Proteins (IAPs) are well-studied E3 ubiquitin ligases predominantly known for regulation of apoptosis. We uncovered that IAPs can function as a direct E3 ubiquitin ligase of RhoGTPase Rac1.
Oberoi-Khanuja, Tripat Kaur   +1 more
core   +1 more source

Clinical and plasma proteomic characterization of heart failure with supranormal left ventricular ejection fraction: An emerging entity of heart failure

open access: yesEuropean Journal of Heart Failure, EarlyView.
Heart failure (HF) with supranormal ejection fraction (HFsnEF) is an unnoticed but emerging entity in HF. This study showed that HFsnEF carries a similarly increased cardiovascular risk as HF with reduced ejection fraction (HFrEF) and distinct structural and proteomic characteristics from HFrEF, warranting a further comprehensive understanding and ...
Yasuhiko Sakata   +19 more
wiley   +1 more source

Topological and functional properties of the small GTPases protein interaction network. [PDF]

open access: yesPLoS ONE, 2012
Small GTP binding proteins of the Ras superfamily (Ras, Rho, Rab, Arf, and Ran) regulate key cellular processes such as signal transduction, cell proliferation, cell motility, and vesicle transport.
Anna Delprato
doaj   +1 more source

Cloning and Expression Pattern of rnd1 and Its Involvement in Disease Resistance in Japanese Flounder (Paralichthys olivaceus)

open access: yesProgress in Fishery Sciences, 2023
Edwardsiella tarda is a major causative pathogen of bacterial ascites in Japanese flounder, leading to massive economic losses, and the discovery of molecular markers linked to disease resistance is an effective strategy in resistance breeding programs ...
Ziwei ZHANG   +5 more
doaj   +1 more source

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