Results 241 to 250 of about 251,198 (269)
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RHO GTPASES: Biochemistry and Biology
Annual Review of Cell and Developmental Biology, 2005Approximately one percent of the human genome encodes proteins that either regulate or are regulated by direct interaction with members of the Rho family of small GTPases. Through a series of complex biochemical networks, these highly conserved molecular switches control some of the most fundamental processes of cell biology common to all eukaryotes ...
Aron B, Jaffe, Alan, Hall
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Plant GTPases: the Rhos in bloom
Trends in Cell Biology, 2000In animal cells and in fungi, small GTP-binding proteins of the Rho family have well-established roles in morphogenesis, cell-cycle progression, gene transcription and the generation of superoxide anions. The presence of these proteins in plant cells, however, has been established only recently, and the role of Rho GTPases in plants is now coming into ...
A H, Valster, P K, Hepler, J, Chernoff
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Rho GTPases and the Actin Cytoskeleton
Science, 1998The actin cytoskeleton mediates a variety of essential biological functions in all eukaryotic cells. In addition to providing a structural framework around which cell shape and polarity are defined, its dynamic properties provide the driving force for cells to move and to divide. Understanding the biochemical mechanisms that control the organization of
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Regulation of Phagocytosis by Rho GTPases
2005Phagocytosis is the mechanism of internalization used by specialized cells such as macrophages, dendritic cells, and neutrophils to internalize, degrade, and eventually present peptides derived from particulate antigens. The phagocytic process comprises several sequential and complex events initiated by the recognition ofligands on the surface of the ...
F, Niedergang, P, Chavrier
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Activation of MEKK1 by Rho GTPases
2006Mammalian MAP/ERK kinase kinase 1 (MEKK1) is MAP kinase kinase kinase (MAP3K) that is a crucial regulator of many cellular signaling cascades. One of the most important physiological functions of MEKK1 is its ability to regulate cell migration, because MEKK1 null mice are defective in eyelid closure.
Zhui, Chen, Melanie H, Cobb
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Historical Overview of Rho GTPases
2011In 1985, the first members of the Rho GTPase family were identified. Over the next 10 years, rapid progress was made in understanding Rho GTPase signalling. Multiple Rho GTPases were discovered in a wide range of eukaryotes, and shown to regulate a diverse range of cellular processes, including cytoskeletal dynamics, NADPH oxidase activation, cell ...
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Plant Rho GTPase signaling promotes autophagy
Molecular Plant, 2021Jinbo Shen, Hao Ye, Ying Zhu
exaly
Rho GTPase regulatory proteins in podocytes
Kidney International, 2021Tomoko Takano, Jun Matsuda
exaly