Results 221 to 230 of about 191,346 (272)

Major Host Factors Involved in Epithelial Cell Invasion of Campylobacter jejuni: Role of Fibronectin, Integrin Beta1, FAK, Tiam-1, and DOCK180 in Activating Rho GTPase Rac1 [PDF]

, 2011
Manja Boehm, Malgorzata Krause-Gruszczynska, Manfred Rohde, Nicole Tegtmeyer, Seiichiro Takahashi, Omar A. Oyarzábal, Steffen Backert   +6 more
openalex   +1 more source

Rho GTPase overexpression impacts leaf internal architecture and mesophyll conductance in Arabidopsis

New Phytologist, Volume 248, Issue 6, Page 3053-3066, December 2025.
Summary Leaves are built from multiple cell types and are structured to enable the conversion of carbon dioxide and water into sugars in the process of photosynthesis. Understanding how cell architecture impacts the movement of CO2 within leaves may provide means to improve photosynthesis.
Isabella Østerlund, Silas Ørting, Alistair Leverett, Guillaume Théroux‐Rancourt, Samira Ebrahimi, Yang Wang, Zoran Nikoloski, Johannes Kromdijk, Staffan Persson   +8 more
wiley   +1 more source

Nε-Fatty acylation of Rho GTPases by a MARTX toxin effector

Science, 2017
Yan Zhou, Chunfeng Huang, Li Yin, Muyang Wan, Xiaofei Wang, Lin Li, Yanhua Liu, Zhao Wang, P. Fu, Ni Zhang, She Chen, Xiaoyun Liu, F. Shao, Yongqun Zhu   +13 more
semanticscholar   +1 more source

Molecular Docking and Target‐Specific Binding Profiles of Benzosuberane‐Based Compounds

ChemMedChem, Volume 20, Issue 21, November 6, 2025.
Benzosuberane represents a promising scaffold in medicinal chemistry. Several benzosuberane‐based derivatives are described in this review as anticancer agents, including antivascular agents, DNA‐intercalators, receptor modulators and kinase inhibitors.
Michail A. Saragatsis, Gemma K. Kinsella, James F. Curtin, Tao Zhang   +3 more
wiley   +1 more source

Approaches of targeting Rho GTPases in cancer drug discovery

Expert Opinion on Drug Discovery, 2015
Yuan Lin, Yi Zheng
semanticscholar   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, Volume 19, Issue 11, Page 3360-3375, November 2025.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

Nanofibrillar scaffolds induce preferential activation of Rho GTPases in cerebral cortical astrocytes

, 2012
Tiryaki VM, Ayres VM, Khan Aa, I Ahmed, Shreiber DI, S Meiners   +5 more
openalex   +1 more source

8-Oxoguanine DNA glycosylase-1-mediated DNA repair is associated with Rho GTPase activation and α-smooth muscle actin polymerization

, 2014
Jixian Luo, Koa Hosoki, Attila Bácsi, Zsolt Radák, Muralidhar L. Hegde, Sanjiv Sur, Tapas K. Hazra, Allan R. Brasier, Xueqing Ba, István Boldogh   +9 more
openalex   +2 more sources

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, Volume 19, Issue 11, Page 3427-3444, November 2025.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source