Results 101 to 110 of about 3,677,140 (187)

Frizzled Proteins are bona fide G Protein-Coupled Receptors [PDF]

open access: yes, 2009
Receptors of the Frizzled family initiate Wnt ligand-dependent signaling controlling multiple steps in organism development and highly conserved in evolution. Misactivation of the Wnt/Frizzled signaling is cancerogenic.
Silke Buestorf, Vladimir L. Katanaev
core  

The cationic region of Rhes mediates its interactions with specific Gβ subunits [PDF]

open access: yes, 2009
Ras homologue enriched in striatum (Rhes) is a small monomeric G protein which functions in a variety of cellular processes, including attenuation of G protein-coupled receptor (GPCR)signalling.
Ladds, Graham   +3 more
core   +1 more source

Novel role of Ras-GTPase Activating Protein SH3 Domain-Binding Protein G3BP in adhesion and migration of 32D myeloid progenitor cells [PDF]

open access: yes, 2012
Rho GTPases are involved in homing and mobilization of hematopoietic stem and progenitor cells due to their impact on cytoskeleton remodeling. We have previously shown that inhibition of Rho, Rac and Cdc42 clearly impairs adhesion of normal and leukemic ...
Schwarz, Kerstin   +8 more
core   +1 more source

Protein import into chloroplasts: new aspects of a well-known topic [PDF]

open access: yes, 2007
Protein import into plant chloroplasts is a fascinating topic that is being investigated by many research groups. Since the majority of chloroplast proteins are synthesised as precursor proteins in the cytosol, they have to be posttranslationally ...
Bölter, Bettina   +2 more
core   +1 more source

The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits

open access: yesInternational Journal of Biological Sciences, 2005
The heterotrimeric G-protein alpha subunit has long been considered a bimodal, GTP-hydrolyzing switch controlling the duration of signal transduction by seven-transmembrane domain (7TM) cell-surface receptors.
doaj  

Genome‐wide association study in 21,271 individuals identifies 9 novel loci associated with circulating CD34+ hematopoietic stem and progenitor cell levels

open access: yes
HemaSphere, Volume 10, Issue 7, July 2026.
Yuwen Xie   +20 more
wiley   +1 more source

Sensor potency of the moonlighting enzyme-decorated cytoskeleton [PDF]

open access: yes, 2013
Background: There is extensive evidence for the interaction of metabolic enzymes with the eukaryotic cytoskeleton. The significance of these interactions is far from clear.
Ripoll, Camille   +5 more
core   +1 more source

Regulation of membrane-bound phospholipase D by protein kinase C in HL60 cells. Synergistic action of small GTP-binding protein RhoA.

open access: yesThe Journal of biological chemistry, 1996
In HL60 cells, the membrane-bound phospholipase D (PLD) was stimulated by 4beta-phorbol 12-myristate 13-acetate (PMA) in the presence of the cytosolic fraction from HL60 cells or rat brain. The cytosolic factor for this PMA-induced PLD activation was subjected to purification from rat brain by sequential chromatographies.
K, Ohguchi   +3 more
openaire   +1 more source

Preprotein recognition and translocation by the Toc complex [PDF]

open access: yes, 2005
Preproptein recognition and translocation across the outer envelope membrane of plastids is catalysed by a proteinaceous machinery, called Toc translocon.
Becker, Thomas
core   +1 more source

G protein-coupled receptor kinase 2-mediated phosphorylation of ezrin is required for G protein-coupled receptor-dependent reorganization of the actin cytoskeleton [PDF]

open access: yes, 2005
G protein-coupled receptor kinase 2 (GRK2) phosphorylates and desensitizes activated G protein-coupled receptors (GPCRs). Here, we identify ezrin as a novel non-GPCR substrate of GRK2. GRK2 phosphorylates glutathione S-transferase (GST)-ezrin, but not an
Pitcher, JA, Cant, SH
core  

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