Characterisation of the benzimidazole-binding site on the cytoskeletal protein tubulin [PDF]
The binding kinetics of several benzimidazole compounds were determined with recombinant tubulin monomers and heterodimers from benzimidazole-sensitive and -insensitive organisms.
MacDonald, Louisa M.
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Conception de biosenseurs des protéines RhoA, RhoB, RhoC [PDF]
Notre équipe s'intéresse à la compréhension des mécanismes de dérégulation des voies de signalisation cellulaire dans la survenue et la maintenance des processus tumoraux, ainsi que leurs conséquences dans la réponse aux thérapies antitumorales.
Chinestra, Patrick
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The Association of Heterotrimeric Gtp-Binding Protein (Go) with Microtubules
The heterotrimeric GTP-binding regulatory proteins (G proteins) play an important role in the regulation of membrane signal transduction. Recently, we identified the association of Go protein with mitotic spindles.
WU, HAN-CHUNG;LIN, CHIN-TARNG +1 more
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Protein-RNA interactions: a structural analysis [PDF]
A detailed computational analysis of 32 protein-RNA complexes is presented. A number of physical and chemical properties of the intermolecular interfaces are calculated and compared with those observed in protein-double-stranded DNA and protein-single ...
Daley, DT +9 more
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Transglutaminase in the life and death of the pancreatic β-cell [PDF]
Tissue transglutaminase (TG2) is a ubiquitous enzyme that catalyses both the Ca2+-dependent formation of protein cross-links via intermolecular isopeptide bonds, and the Ca2+-independent hydrolysis of GTP.
Dookie, S
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The effects of RhoA phosphorylation on the activation of RhoA.
(A) The activity of wild type and various mutant RhoA proteins in response to EGF. COS-7 cells were transfected with expression constructs encoding wild type and mutant GFP-tagged RhoA proteins.
Junfeng Tong (805234) +3 more
core +1 more source
Additions and Corrections to The Caenorhabditis elegans small GTP-binding protein RhoA is enriched in the nerve ring and sensory neurons during larval development. [PDF]
Weining Chen, Louis Lim
openaire +1 more source
AWAI, Toshinari +5 more
openaire +2 more sources
Non-canonical and constitutive activation of small GTPases: more than an exception to the rule? [PDF]
Kiers J, Hordijk PL.
europepmc +1 more source
A systems and molecular analysis of G protein-mediated signalling [PDF]
The ability of cells to respond correctly to signals from their microenvironment is an essential prerequisite of life. Many external signals are detected through G protein-coupled receptor (GPCR) signalling pathways, which control all aspects of ...
Croft, Wayne D.
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