Results 71 to 80 of about 8,462 (144)

Suppressing Glycerol‐3‐phosphate Phosphatase and Enhancing Glycerol‐3‐Phosphate Shuttle Flux Crucial for High‐Efficiency Fatty Acid Production in the Fast‐Growing Oleaginous Schizochytrium

Advanced Science, Volume 12, Issue 45, December 4, 2025.
This study establishes an efficient oleaginous heterotrophic microalga, Schizochytrium, through chassis optimization and metabolic engineering, significantly enhancing fatty acid titers and productivities. It also identifies a regulatory mechanism that coordinates biomass and lipid synthesis, providing a rational target for metabolic pathway rewiring ...
Fangzhong Wang, Weijia Jin, Tiantian Wang, Junkai Ji, Kun Cao, Jianqiang Li, Lei Chen, Weiwen Zhang   +7 more
wiley   +1 more source

Engineering Strategies for Fungal Cell Disruption in Biotechnological Applications

Engineering in Life Sciences, Volume 25, Issue 12, December 2025.
ABSTRACT Fungal cell disruption plays a critical role in unlocking a wide range of high‐value intracellular products such as lipids, proteins, pigments, and bioactive compounds. However, lysing fungal cells is far more challenging than breaking bacterial or algal cells due to their robust and highly structured cell walls.
Bhagyeshri Ulhas Mantri, Maliheh Vahidinasab, Sonja Berensmeier   +2 more
wiley   +1 more source

Bioactive Compounds Derived From Natural Foods Against Metabolic Syndrome and the Advances of Resveratrol and Caffeic Acid in Microbial Cell Factory Production: A Review

Food Frontiers, Volume 6, Issue 6, Page 2575-2590, November 2025.
Metabolic syndrome is characterized by abdominal obesity, hyperglycemia, dyslipidemia, and hypertension. Bioactive compounds extracted from herbs, tea, and coffee using microbial cell factories, particularly resveratrol and caffeic acid, have demonstrated remarkable potential in the management of metabolic syndrome, offering innovative solutions for ...
Tao Li, Jingjing Shi, Tao Liu, Chongxiang Xue, Lin Han, Mingzhe Zhang, Linhua Zhao, Xiaolin Tong   +7 more
wiley   +1 more source

FT-NIR: a tool for rapid intracellular lipid quantification in oleaginous yeasts

Biotechnology for Biofuels, 2019
Background Lipid extraction for quantification of fat content in oleaginous yeasts often requires strong acids and harmful organic solvents; it is laborious and time-consuming. Therefore, in most cases just endpoint measurements of lipid accumulation are
Mikołaj Chmielarz, Sabine Sampels, Johanna Blomqvist, Jule Brandenburg, Frida Wende, Mats Sandgren, Volkmar Passoth   +6 more
doaj   +1 more source

Basidiomycete Yeasts of Wine Grapes and Their Potential Applications in Winemaking

Comprehensive Reviews in Food Science and Food Safety, Volume 24, Issue 6, November 2025.
ABSTRACT Vineyards support highly diverse communities of native yeasts, but only a small proportion are fermentative ascomycetes capable of alcoholic fermentation. Many non‐fermentative species are also present, including a range of metabolically active basidiomycete yeasts that can influence wine aromatic profiles, especially in the early stages of ...
Adele Bunbury‐Blanchette, Lihua Fan, Allison Walker, Gavin Kernaghan   +3 more
wiley   +1 more source

Chromosome-level genome assembly and transcriptome-based annotation of the oleaginous yeast Rhodotorula toruloides CBS 14 [Elektronisk resurs]

, 2021
Rhodotorula toruloides is an oleaginous yeast with high biotechnological potential. In order to understand the molecular physiology of lipid synthesis in R. toruloides and to advance metabolic engineering, a high-resolution genome is required.
Passoth, Volkmar,, Chmielarz, Mikolaj,, Sveriges lantbruksuniversitet., Martín Hernández, Giselle De La Caridad,, Müller, Bettina,, Hoelzer, Martin,, Viehweger, Adrian,, Brandt, Christian,, Swedish University of Agricultural Sciences.   +8 more
core   +1 more source

Acidification by nitrogen metabolism triggers extracellular biopolymer production in an oleaginous yeast

Applied and Environmental Microbiology
The oleaginous yeast Rhodotorula toruloides is a natural producer of lipids and carotenoids. However, its potential as a producer of extracellular biopolymers remains unexplored. Hence, we aimed to evaluate the R.
Henrique Sepúlveda Del Rio Hamacek, Oksana Tingajeva, Katharina Ostertag, Alīna Reķēna, Aleksandr Illarionov, Piia Jõul, Paola Monteiro de Oliveira, Giselle de La Caridad Martín-Hernández, Bettina Müller, Nemailla Bonturi, Volkmar Passoth, Petri-Jaan Lahtvee, Rahul Kumar   +12 more
doaj   +1 more source

Identification, Quantification and Kinetic Study of Carotenoids and Lipids in Rhodotorula toruloides CBS 14 Cultivated on Wheat Straw Hydrolysate

Fermentation, 2022
Production of carotenoids and lipids by Rhodotorula toruloides CBS 14 cultivated on wheat straw hydrolysate was investigated. An ultra-high-performance liquid chromatography (UHPLC) method for carotenoid quantification was developed and validated ...
Yashaswini Nagavara Nagaraj, Viktoriia Burkina, Laura Okmane, Johanna Blomqvist, Alexander Rapoport, Mats Sandgren, Jana Pickova, Sabine Sampels, Volkmar Passoth   +8 more
doaj   +1 more source

Brazilian Biomes as Promising Resources of Rhodotorula Yeasts for the Biotechnological Production of Carotenoids

Chemistry &Biodiversity, Volume 22, Issue 10, October 2025.
ABSTRACT Yeasts belonging to the genus Rhodotorula are capable of synthesizing carotenoids, such as β‐carotene, γ‐carotene, torulene, torularodine, and astaxanthin. These carotenoids have been shown to offer health benefits to humans, such as immune system strengthening and a reduced risk of chronic degenerative diseases.
David Cristian Rodrigues Lucas, Renan Campos Chisté   +1 more
wiley   +1 more source

Lipid Metabolism Optimisation in Ashbya gossypii to Produce Microbial Oils From Xylose‐Rich Feedstocks

Microbial Biotechnology, Volume 18, Issue 8, August 2025.
A multigenic strategy enhanced lipid production in a xylose‐utilising strain of Ashbya gossypii by boosting acetyl‐CoA and NADPH supply while blocking β‐oxidation. The engineered strain reached 60% oil content when grown on sugar mixtures simulating xylose‐rich feedstocks.
Javier‐Fernando Montero‐Bullón, Javier Martín‐González, Gloria Muñoz‐Fernández, Rubén M. Buey, Alberto Jiménez   +4 more
wiley   +1 more source