Rhoifolin improves bleomycin-induced fibrosis in vivo and cell damage in vitro both related to NRF2/HO-1 pathway [PDF]
BMC Pulmonary MedicineBackground Pulmonary fibrosis (PF) is a chronic interstitial lung illness characterized by its high worldwide prevalence, unknown etiology, and dismal prognosis.
Xuehua Wang +9 more
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Rhoifolin Ameliorates Osteoarthritis via Regulating Autophagy [PDF]
Frontiers in Pharmacology, 2021 Osteoarthritis (OA) is a common age-related joint disease. Its development has been generally thought to be associated with inflammation and autophagy.
Jiyuan Yan +8 more
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Ameliorative Effects of Rhoifolin in Scopolamine-Induced Amnesic Zebrafish (Danio rerio) Model [PDF]
Antioxidants, 2020 Rhoifolin (Rho) exerts many biological activities such as anticancer, antidiabetic, hepatoprotective, antirheumatic, antibacterial, and antiviral properties. The neuroprotective action of this compound has not been studied.
Ion Brinza +5 more
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Scientific Reports, 2022 This study aimed to evaluate the anti-pancreatic cancer effects of flavonoids in Plumula Nelumbinis. High-performance liquid chromatography/quadrupole time-of-flight mass spectrometry showed that apiin, rhoifolin, and vitexin were three principal ...
Bingxin Zheng +4 more
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Rhoifolin regulates oxidative stress and proinflammatory cytokine levels in Freund’s adjuvant-induced rheumatoid arthritis via inhibition of NF-κB [PDF]
Brazilian Journal of Medical and Biological Research, 2020 Rheumatoid arthritis (RA) is an autoimmune disease of knee joints involving pain and inflammation. Rhoifolin is a plant flavonoid known to have antioxidant and anti-inflammatory properties.
Shanqin Peng +6 more
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Frontiers in Pharmacology, 2022 Background: Alcoholic liver disease (ALD) is a common chronic liver disorder worldwide, which is detrimental to human health. A preliminary study showed that the total flavonoids within Citrus grandis “Tomentosa” exerted a remarkable effect on the ...
Baoyu Mai +12 more
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Pea eggplant (Solanum torvum Swartz) is a source of plant food polyphenols with SARS-CoV inhibiting potential [PDF]
PeerJ, 2022 Background Pea eggplant (Solanum torvum Swartz) commonly known as turkey berry or ‘terung pipit’ in Malay is a vegetable plant widely consumed by the local community in Malaysia. The shrub bears pea-like turkey berry fruits (TBFs), rich in phytochemicals
Nisha Govender +4 more
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Rhoifolin potentiates the anti-cancer activity of doxorubicin in MDA-MB-231 triple-negative breast cancer cells [PDF]
PharmaciaBackground: The combination of chemotherapeutic agents with natural compounds has gained attention as a strategy to improve treatment effectiveness and reduce adverse effects of cancer therapies.
Ahmad Saleh Al-Radaideh +5 more
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Determination of bioactive and anti-inflammatory molecules of Thymbra spicata L. from Mardin by GC–MS and LC–Orbitrap HRMS: a DFT, molecular docking, ADMET, biological target and activity study [PDF]
BMC Complementary Medicine and TherapiesObjectives In this study, phenolic compounds (PC), volatile compounds (VC), antioxidant, anti-inflammatory, and antimicrobial properties of the Thymbra spicata L. plant grown in the Mardin Yeşilli region were investigated.
Velid Unsal +2 more
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Wound-Healing Potential of Rhoifolin-Rich Fraction Isolated from Sanguisorba officinalis Roots Supported by Enhancing Re-Epithelization, Angiogenesis, Anti-Inflammatory, and Antimicrobial Effects [PDF]
Pharmaceuticals, 2022 A wound is a complicated bioprocess resulting in significant tissue damage, which is worsened by a secondary bacterial infection, commonly Pseudomonas aeruginosa and Staphylococcus aureus.
Walaa A. Negm +6 more
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