Results 21 to 30 of about 291 (141)

Potential of Plant Bioactive Compounds as SARS-CoV-2 Main Protease (Mpro) and Spike (S) Glycoprotein Inhibitors: A Molecular Docking Study

open access: yesScientifica, 2020
Since the outbreak of the COVID-19 (coronavirus disease 19) pandemic, researchers have been trying to investigate several active compounds found in plants that have the potential to inhibit the proliferation of SARS-CoV-2 (severe acute respiratory ...
Trina Ekawati Tallei   +8 more
doaj   +2 more sources

An Efficient Method for the Preparative Isolation and Purification of Flavonoid Glycosides and Caffeoylquinic Acid Derivatives from Leaves of Lonicera japonica Thunb. Using High Speed Counter-Current Chromatography (HSCCC) and Prep-HPLC Guided by DPPH-HPLC Experiments

open access: yesMolecules, 2017
In this work, the n-butanol extract from leaves of Lonicera japonica Thunb. (L. japonica) was reacted with DPPH and subjected to a HPLC analysis for the guided screening antioxidants (DPPH-HPLC experiments). Then, nine antioxidants, including flavonoid
Daijie Wang   +7 more
doaj   +2 more sources

Comparison of Flavonoid Compounds in the Flavedo and Juice of Two Pummelo Cultivars (Citrus grandis L. Osbeck) from Different Cultivation Regions in China

open access: yesMolecules, 2014
The objective of this study was to investigate the effect of different cultivation regions on the pattern and content of flavonoids in two pummelo cultivars (C. grandis L. Osbeck) in China.
Mingxia Zhang   +4 more
doaj   +2 more sources

Jiuwei Xiaozhi Decoction Alleviates High‐Fat Diet‐Induced MASLD by Suppressing Hepatic SREBP2‐Driven Cholesterogenesis and Restoring PPARα‐Mediated Fatty Acid Oxidation

open access: yesChemical Biology &Drug Design, Volume 108, Issue 2, August 2026.
Studies have found that Jiuwei Xiaozhi Decoction can improve high‐fat diet‐induced fatty liver disease, mainly by regulating the SREBP2 and PPARα pathways to balance hepatic lipid metabolism while reducing inflammatory responses. ABSTRACT Jiuwei Xiaozhi Decoction (JWXZ) is a nine‐herb traditional Chinese medicine formula clinically used for hepatic ...
Youcheng Ma   +5 more
wiley   +2 more sources

Inhibition of SARS-CoV 3CL protease by flavonoids

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2020
There were severe panics caused by Severe Acute Respiratory Syndrome (SARS) and Middle-East Respiratory Syndrome-Coronavirus. Therefore, researches targeting these viruses have been required.
Seri Jo   +3 more
doaj   +2 more sources

Mechanistic evaluation of niosomal Rhoifolin in antileishmanial therapy and its additive potential with meglumine antimoniate

open access: yesScientific Reports
Leishmaniasis is a neglected tropical disease that urgently requires safer and more effective therapeutic strategies. Rhoifolin (RF), a natural flavonoid with anti-inflammatory and antiparasitic potential, has shown promising biological activities ...
Raheleh Eftekhari Kenzerki   +6 more
doaj   +2 more sources

Rhoifolin improves bleomycin-induced fibrosis in vivo and cell damage in vitro both related to NRF2/HO-1 pathway

open access: yesBMC Pulmonary Medicine
Background Pulmonary fibrosis (PF) is a chronic interstitial lung illness characterized by its high worldwide prevalence, unknown etiology, and dismal prognosis.
Xuehua Wang   +9 more
doaj   +3 more sources

Network pharmacology, bioinformatics and in vitro/in vivo validation elucidate the anti-lung cancer activities and potential targets of Rhoifolin

open access: yesFrontiers in Pharmacology
BackgroundRhoifolin (ROF), a naturally occurring flavonoid, exhibits broad bioactivities, but its therapeutic potential and underlying mechanisms in lung cancer remain largely unknown.
Jing Qian   +6 more
doaj   +3 more sources

Analysis of physicochemical and phytonutrients properties of bastard oleaster fruits and its mass prediction using artificial neural network model [PDF]

open access: yesJournal of Agriculture and Food Research
Bastard oleaster (Elaeagnus latifolia) is highly nutritious, rich in various vitamins (A, C, E) and minerals (P, K, Ca, Mg, Na), yet remains underutilized despite its immense potential.
Raju Sasikumar   +3 more
doaj   +2 more sources

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