Results 11 to 20 of about 1,365 (165)

Rhoifolin improves bleomycin-induced fibrosis in vivo and cell damage in vitro both related to NRF2/HO-1 pathway [PDF]

BMC Pulmonary Medicine
Background Pulmonary fibrosis (PF) is a chronic interstitial lung illness characterized by its high worldwide prevalence, unknown etiology, and dismal prognosis.
Xuehua Wang, Qing Wang, Panyu Zhou, Junhong Zhang, Haojie Su, Fanlu Liu, Jingjing Wu, Fengxia Xiao, Liang Liu, Ling Han   +9 more
doaj   +4 more sources

Rhoifolin Ameliorates Osteoarthritis via Regulating Autophagy [PDF]

Frontiers in Pharmacology, 2021
Osteoarthritis (OA) is a common age-related joint disease. Its development has been generally thought to be associated with inflammation and autophagy.
Jiyuan Yan, Bowei Ni, Gaohong Sheng, Yingchi Zhang, Yifan Xiao, Yongzhuang Ma, Hao Li, Hua Wu, Chang Tu   +8 more
doaj   +3 more sources

Ameliorative Effects of Rhoifolin in Scopolamine-Induced Amnesic Zebrafish (Danio rerio) Model [PDF]

Antioxidants, 2020
Rhoifolin (Rho) exerts many biological activities such as anticancer, antidiabetic, hepatoprotective, antirheumatic, antibacterial, and antiviral properties. The neuroprotective action of this compound has not been studied.
Ion Brinza, Ahmed M. Abd-Alkhalek, Mohamed A. El-Raey, Razvan Stefan Boiangiu, Omayma A. Eldahshan, Lucian Hritcu   +5 more
doaj   +3 more sources

Rhoifolin regulates oxidative stress and proinflammatory cytokine levels in Freund’s adjuvant-induced rheumatoid arthritis via inhibition of NF-κB [PDF]

Brazilian Journal of Medical and Biological Research, 2020
Rheumatoid arthritis (RA) is an autoimmune disease of knee joints involving pain and inflammation. Rhoifolin is a plant flavonoid known to have antioxidant and anti-inflammatory properties.
Shanqin Peng, Congqi Hu, Xi Liu, Lei Lei, Guodong He, Chenming Xiong, Wenqian Wu   +6 more
doaj   +5 more sources

Computational screening combined with well-tempered metadynamics simulations identifies potential TMPRSS2 inhibitors [PDF]

Scientific Reports
Type-II transmembrane serine proteases are effective pharmacological targets for host defence against viral entry and in certain cancer cell progressions.
C. S. Sharanya, D. Sasikala Wilbee, Shijulal Nelson Sathi, Kathiresan Natarajan   +3 more
doaj   +2 more sources

Pea eggplant (Solanum torvum Swartz) is a source of plant food polyphenols with SARS-CoV inhibiting potential [PDF]

PeerJ, 2022
Background Pea eggplant (Solanum torvum Swartz) commonly known as turkey berry or ‘terung pipit’ in Malay is a vegetable plant widely consumed by the local community in Malaysia. The shrub bears pea-like turkey berry fruits (TBFs), rich in phytochemicals
Nisha Govender, Norazura Syazlin Zulkifli, Nurul Farhana Badrul Hisham, Nur Syatila Ab Ghani, Zeti-Azura Mohamed-Hussein   +4 more
doaj   +3 more sources

Research progress on phytochemistry and pharmacology of <i>Staphylea arguta</i> (Lindl.) Byng & Christenh. and prediction of quality markers: a review. [PDF]

Front Pharmacol
BackgroundStaphylea arguta (Lindl.) Byng & Christenh. [Staphyleaceae] (Staphylea arguta), a tree or shrub species belonging to the Staphyleaceae family, is widely distributed in subtropical regions of China, particularly in Jiangxi Province, where it
Cui H, Wei Z, Feng C, Tao X, Yi J.
europepmc   +3 more sources

Rhoifolin potentiates the anti-cancer activity of doxorubicin in MDA-MB-231 triple-negative breast cancer cells [PDF]

Pharmacia
Background: The combination of chemotherapeutic agents with natural compounds has gained attention as a strategy to improve treatment effectiveness and reduce adverse effects of cancer therapies.
Ahmad Saleh Al-Radaideh, Manal A. Abbas, Aya Y. Al-Kabariti, Moath Alqaraleh, Razan Madi, Razan Obeidat   +5 more
doaj   +4 more sources

Determination of bioactive and anti-inflammatory molecules of Thymbra spicata L. from Mardin by GC–MS and LC–Orbitrap HRMS: a DFT, molecular docking, ADMET, biological target and activity study [PDF]

BMC Complementary Medicine and Therapies
Objectives In this study, phenolic compounds (PC), volatile compounds (VC), antioxidant, anti-inflammatory, and antimicrobial properties of the Thymbra spicata L. plant grown in the Mardin Yeşilli region were investigated.
Velid Unsal, Leyla Ercan, Cemile Gunbegi Calıskan   +2 more
doaj   +2 more sources

Unlocking the Potential of Bioactive Compounds in Pancreatic Cancer Therapy: A Promising Frontier. [PDF]

Biomolecules
Pancreatic ductal adenocarcinoma (PDA) is a highly challenging malignancy to treat, with a high mortality rate and limited therapeutic options. Despite advances in cancer research, the prognosis for patients diagnosed with PDA is often poor due to late ...
Brugiapaglia S, Spagnolo F, Curcio C.
europepmc   +3 more sources