Results 11 to 20 of about 291 (141)

Rhoifolin: A promising flavonoid with potent cytotoxic and anticancer properties

EXCLI Journal : Experimental and Clinical Sciences
Rhoifolin is a flavonoid found in various plant species, especially within the Rutaceae family, and is considered a dietary component due to its presence in edible plants. Its bioactive properties, such as cytotoxic and anticancer activities, have gained
Ceyda Sibel Kılıç, Mehmet Murat Kışla, Gülin Amasya, Ceyda Tuğba Şengel-Türk, Zeynep Ateş Alagöz, Ayşe Mine Gençler Özkan, İlker Ateş, Safa Gümüşok, Jesús Herrera-Bravo, Javad Sharifi-Rad, Daniela Calina   +10 more
doaj   +4 more sources

Rhoifolin potentiates the anti-cancer activity of doxorubicin in MDA-MB-231 triple-negative breast cancer cells [PDF]

Pharmacia
Background: The combination of chemotherapeutic agents with natural compounds has gained attention as a strategy to improve treatment effectiveness and reduce adverse effects of cancer therapies.
Ahmad Saleh Al-Radaideh, Manal A. Abbas, Aya Y. Al-Kabariti, Moath Alqaraleh, Razan Madi, Razan Obeidat   +5 more
doaj   +5 more sources

Efficient In Vitro Propagation of Turpinia arguta and Quantitative Analysis of Its Ligustroflavone and Rhoifolin Content

Horticulturae
Turpinia arguta is an excellent medicinal plant mainly used for the treatment of pharyngitis, tonsillitis, and tonsillar abscesses. However, an efficient regeneration protocol using tissue cultures for T. arguta does not exist.
Jiangmei Hu, Junhuo Cai, Xinrui Hu, Lijun Wang, Qiangqiang Cheng, Xiuhua Tao   +5 more
doaj   +3 more sources

Effect of the plant flavonoid, rhoifolin, on memory and cognition in a rat model of Alzheimer’s disease [PDF]

Tropical Journal of Pharmaceutical Research, 2022
Purpose: To investigate the neuroprotective effect of the natural flavonoid rhoifolin in rats with streptozotocin (STZ)-induced (AD). Methods: Morris water-maze and novel object recognition tests were carried out to estimate the effect of rhoifolin on ...
Wei, Yanbin, Wu, Shaochang, Jiang, Ruilai, Meng, Shuiyun, Huang, Xiaocheng   +4 more
core   +3 more sources

Wound-Healing Potential of Rhoifolin-Rich Fraction Isolated from Sanguisorba officinalis Roots Supported by Enhancing Re-Epithelization, Angiogenesis, Anti-Inflammatory, and Antimicrobial Effects

Pharmaceuticals, 2022
A wound is a complicated bioprocess resulting in significant tissue damage, which is worsened by a secondary bacterial infection, commonly Pseudomonas aeruginosa and Staphylococcus aureus.
Walaa A. Negm, Aya H. El-Kadem, Engy Elekhnawy, Nashwah G. M. Attallah, Gadah Abdulaziz Al-Hamoud, Thanaa A. El-Masry, Ahmed Zayed   +6 more
doaj   +2 more sources

Rhoifolin Improves Glycometabolic Control in Streptozotocin-Induced Diabetic Rats by Up-Regulating the Expression of Insulin Signaling Proteins and Down-Regulating the MAPK/JNK Pathway

Pharmaceuticals
Background and Aim: Rhoifolin is a bioactive flavonoid that possesses strong antioxidant and anti-inflammatory activities. The current investigation aimed to examine the anti-diabetic potential of rhoifolin in streptozotocin-induced diabetic rats.
Maryam Ehsan, Sibtain Ahmed, Wafa Majeed, Asra Iftikhar, Maryam Iftikhar, Mateen Abbas, Tahir Mehmood   +6 more
doaj   +2 more sources

Climate Influence on Leaf Appearance and Ligustroflavone and Rhoifolin Compounds of Turpinia arguta (Lindl.) Seem. from Different Chinese Habitats

Horticulturae
The dry leaf of Turpinia arguta (Lindl.) Seem. is used in traditional Chinese medicine as a quick-acting product for sore throat and pharyngitis relief. Samples of T.
Hongli Ji, Junhuo Cai, Chao Chen, Xiaomin Song, Yun Luo, Jinbao Yu, Yang Zhang, Xiuhua Tao   +7 more
doaj   +2 more sources

Rhoifolin Alleviates Ulcerative Colitis by Targeting NMNAT1 and Activating SIRT1‐FOXO1 Signaling to Enhance ILC3s Effector Function

Advanced Science, EarlyView.
Rhoifolin directly targets NMNAT1, thereby activating nicotinamide salvage pathway and promoting intracellular NAD+ biosynthesis. Elevated NAD+ levels enhance SIRT1 activity, leading to FOXO1 deacetylation and nuclear translocation. Nuclear FOXO1 subsequently binds to the IL‐22 promoter, upregulating IL‐22 transcription and potentiating ILC3 effector ...
Hongqiong Yang, Yishu Zhang, Sijia Feng, Xiaoqing Ma, Jiayi Feng, Junwei Wang, Jialin Gao, An Pan, Dapeng Wu, Kang Ding, Caijuan Zheng, Qi Lv, Lihong Hu   +12 more
wiley   +2 more sources

Analysis of Floral Color Differences between Different Ecological Conditions of Clematis tangutica (Maxim.) Korsh

Molecules, 2023
The Clematis tangutica (Maxim.) Korsh. is a wild flowering plant that is most widely distributed on the Qinghai–Tibet Plateau, with beautiful, brightly colored flowers and good ornamental properties and adaptability.
Xiaozhu Guo, Gui Wang, Juan Li, Jiang Li, Xuemei Sun   +4 more
doaj   +2 more sources

Extreme transgressive segregation for rhoifolin reveals breeding potential in strawberry F1 hybrids

Food Chemistry
Rhoifolin, a bioactive flavonoid with demonstrated anti-inflammatory and neuroprotective properties, represents an untapped opportunity for developing functional strawberries.
Vallarino, José G, Capocasa, Franco, Osorio, Sonia, Qaderi, Rohullah, Mezzetti, Bruno, Mazzoni, Luca   +5 more
core   +3 more sources