Results 51 to 60 of about 985 (148)

Inhibition of angiotensin-converting enzyme activity by flavonoids: structure-activity relationship studies. [PDF]

open access: yesPLoS ONE, 2012
Previous studies have demonstrated that certain flavonoids can have an inhibitory effect on angiotensin-converting enzyme (ACE) activity, which plays a key role in the regulation of arterial blood pressure.
Ligia Guerrero   +6 more
doaj   +1 more source

Analysis of Chemical Components and Blood‐Absorbed Components in Youjing Granules by UHPLC‐Q‐Orbitrap‐MS

open access: yesAnalytical Science Advances, Volume 6, Issue 2, December 2025.
ABSTRACT This study investigates the chemical components of Youjing Granules (YG) and identifies blood‐absorbed components in rat serum following YG administration via gavage. Chemical components and blood‐absorbed components of YG were analysed and identified using ultra‐high‐performance liquid chromatography coupled with hybrid quadrupole‐orbitrap ...
Mingxin Guo   +5 more
wiley   +1 more source

COVID-19: General Strategies for Herbal Therapies

open access: yesJournal of Evidence-Based Integrative Medicine, 2022
The coronavirus disease-2019 (COVID-19) pandemic started in early 2020 with the outbreak of a highly pathogenic human coronavirus. The world is facing a challenge and there is a pressing need for efficient drugs. Plants and natural compounds are a proven
Samaneh Soleymani PharmD, PhD   +7 more
doaj   +1 more source

Centaurea lycaonica Extracts Induce Apoptosis in HeLa Human Cervical Cancer Cells via Bax/Bcl‐2 Modulation and Caspase Activation: An LC‐HRMS‐Based Study

open access: yesFood Science &Nutrition, Volume 13, Issue 7, July 2025.
This study highlights the pharmacological mechanisms of dichloromethane (CHD) and methanol (CHM) extracts of Centaurea lycaonica Boiss. & Heldr. herba as the induction of apoptosis on HeLa cells. Apoptotic properties of CHD and CHM are through suppression of Bcl‐2 and increase in Bax, caspase 9, and 3 activities on HeLa cells.
Ayşe Kübra Karaboğa Arslan   +4 more
wiley   +1 more source

Identification of Yunnan Guangnan Dendrobium officinale With Different Growth Years Using UHPLC–Orbitrap–MS

open access: yeseFood, Volume 6, Issue 3, June 2025.
ABSTRACT Dendrobium officinale from Guangnan was screened nontargeted using UHPLC–Orbitrap‐MS for different growth years. OPLS‐DA effectively differentiated D. officinale based on growth years, identifying 70 different compounds. Eight indole diketopiperazine alkaloids did not differ considerably among the growth years. The differential compounds of D.
Jiao Zhang   +7 more
wiley   +1 more source

Comparison of the bioactive chemical components and antioxidant activities in three tissues of six varieties of Citrus grandis ‘Tomentosa’ fruits

open access: yesInternational Journal of Food Properties, 2019
The total phenolic, flavonoid, coumarin, and volatile contents and antioxidant activities in three tissues of six Citrus grandis ‘Tomentosa’ (CGT) fruit varieties were investigated. Two flavones, 3 coumarins and 147 volatiles were identified. The exocarp
Ruiyi Fan   +3 more
doaj   +1 more source

Aerial Part Extract of as an Anti-Blood Stasis Agent in a Mouse Model of Hen-egg White Lysozyme-Induced Stagnant Blood Flow

open access: yesNatural Product Communications, 2023
Background/Objective Stagnant blood ( oketsu in Japanese) is considered a severe pathological condition in traditional Chinese and Japanese medicine. Kummerowia striata is known as a weed in Japan; however, in traditional Chinese medicines, it is used ...
Shui Aoki   +4 more
doaj   +1 more source

Traceability and Adulteration Analysis of Citri Reticulatae Pericarpium Based on “Digital Identity Card” and UHPLC‐QTOF‐MS Analysis

open access: yesFood Science &Nutrition, Volume 13, Issue 5, May 2025.
GRP's origin traceability and adulteration analysis can be effectively and accurately realized on the basis of UHPLC‐QTOF‐MS analysis and “digital identity card.” It has important reference significance for the quick digital analysis of traceability and adulteration of CRPs and digital quality control of Chinese medicines.
Xianrui Wang   +9 more
wiley   +1 more source

The Phenolic Signature of Psidium cattleianum Fruits and Leaves Modulates TRPV1 and TRPA1 Transient Receptor Potential Channels: A Metabolomics, In Vitro, and In Silico Study

open access: yesFood Science &Nutrition, Volume 13, Issue 4, April 2025.
An untargeted metabolomics study was performed to find the encompassed phytochemicals in the fruit and leaf extract of Psidium cattleianum. This enabled the annotation of 469 compounds belonging to different phenolic subclasses, with a predominance of flavonoids and phenolics.
Leilei Zhang   +13 more
wiley   +1 more source

Phytochemical Screening, Antibacterial, Antifungal, Antiviral, Cytotoxic, and Anti-Quorum-Sensing Properties of Teucrium polium L. Aerial Parts Methanolic Extract

open access: yesPlants, 2020
The chemical profile of Teucrium polium L. (T. polium) methanolic extract was tested using liquid chromatography coupled with high resolution mass spectrometry (HR-LCMS). Disc diffusion and microdilution assays were used for the antimicrobial activities.
Mousa Alreshidi   +12 more
doaj   +1 more source

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