Results 71 to 80 of about 291 (141)

Fat Browning Effects of Catalpol and Rhoifolin from Rehmannia glutinosa (Gaertn.) and Lonicera japonica (Thunb.) in 3T3-L1 Adipocytes via the β3-AR Signaling Pathway

Pharmaceuticals
Background/Objectives: Promoting white adipose tissue (WAT) browning into thermogenic beige adipocytes is a promising anti-obesity strategy. Yanggyeoksanhwa-tang (YST) has been used traditionally to alleviate obesity-related conditions.
Seung Min Choi, Sung Ho Lim, Ho Seon Lee, Gayoung Choi, Myeong Ji Kim, Hyunwoo Kim, Chang-Ik Choi   +6 more
doaj   +1 more source

COVID-19: General Strategies for Herbal Therapies

Journal of Evidence-Based Integrative Medicine, 2022
The coronavirus disease-2019 (COVID-19) pandemic started in early 2020 with the outbreak of a highly pathogenic human coronavirus. The world is facing a challenge and there is a pressing need for efficient drugs. Plants and natural compounds are a proven
Samaneh Soleymani PharmD, PhD, Ayeh Naghizadeh MD, PhD, Mehrdad Karimi MD, PhD, Azadeh Zarei MD, Raefeh Mardi MD, Gholamreza Kordafshari MD, PhD, Niusha Esmaealzadeh PharmD, Arman Zargaran PharmD, PhD   +7 more
doaj   +1 more source

Fermentation‐Assisted Valorization: A Sustainable Strategy for Turning Fruit By‐Products Into Value‐Added Food Supplements

Food Frontiers, Volume 7, Issue 1, January 2026.
ABSTRACT A substantial proportion of fresh fruit undergoes processing, resulting in underutilized fruit by‑products (FBPs) that are rich in dietary fiber and bioactive compounds. Recent FBP valorization trends demonstrate that fermentation significantly enhances microbiological, nutritional, and sensory attributes, yielding value‑added food supplements.
Abouzar Ghasemi, Salwa Karboune, Denis Groleau, Ismail Fliss   +3 more
wiley   +1 more source

Rhoifolin Improves Bleomycin-induced Fibrosis in Vivo and in Vitro through NRF2/HO-1 Pathway

, 2023
Abstract Purpose: An investigation shows that COVID-19's convalescing pulmonary lesions will experience varying degrees of fibrosis after being inspected by an imaging test. Traditional Chinese medicine frequently treats pulmonary fibrosis using honeysuckle.
Xuehua Wang, Qing Wang, Panyu Zhou, Junhong Zhang, Haojie Su, Fanlu Liu, Jingjing Wu, Ling Han, Liang Liu, Fengxia Xiao   +9 more
openaire   +1 more source

Analysis of Chemical Components and Blood‐Absorbed Components in Youjing Granules by UHPLC‐Q‐Orbitrap‐MS

Analytical Science Advances, Volume 6, Issue 2, December 2025.
ABSTRACT This study investigates the chemical components of Youjing Granules (YG) and identifies blood‐absorbed components in rat serum following YG administration via gavage. Chemical components and blood‐absorbed components of YG were analysed and identified using ultra‐high‐performance liquid chromatography coupled with hybrid quadrupole‐orbitrap ...
Mingxin Guo, Jiaqi Zeng, Xuping Jiang, Wenjiao Zhu, Zhian Tang, Tieliang Ma   +5 more
wiley   +1 more source

Comparison of the bioactive chemical components and antioxidant activities in three tissues of six varieties of Citrus grandis ‘Tomentosa’ fruits

International Journal of Food Properties, 2019
The total phenolic, flavonoid, coumarin, and volatile contents and antioxidant activities in three tissues of six Citrus grandis ‘Tomentosa’ (CGT) fruit varieties were investigated. Two flavones, 3 coumarins and 147 volatiles were identified. The exocarp
Ruiyi Fan, Congyi Zhu, Diyang Qiu, Jiwu Zeng   +3 more
doaj   +1 more source

Aerial Part Extract of as an Anti-Blood Stasis Agent in a Mouse Model of Hen-egg White Lysozyme-Induced Stagnant Blood Flow

Natural Product Communications, 2023
Background/Objective Stagnant blood ( oketsu in Japanese) is considered a severe pathological condition in traditional Chinese and Japanese medicine. Kummerowia striata is known as a weed in Japan; however, in traditional Chinese medicines, it is used ...
Shui Aoki, Hisae Oku, Fumika Kitagawa, Naoki Inoue, Chie Honda   +4 more
doaj   +1 more source

Metabolomics Revealed the Differential Metabolites of Different Broomcorn Millet Varieties in Shanxi

Food Science &Nutrition, Volume 13, Issue 9, September 2025.
A total of 1119 metabolites were identified among different varieties of millet, including 16 major categories such as phenols, alkaloids, and phenylpropanoids. The main pathways of differences among different varieties of millet include tryptophan metabolism, purine metabolism, phenylalanine metabolism, etc. The grain color correlates with β‐carotene,
Chao Jiang, Jiao Mao, Xiaoqiang Song, Hai Li, Xiaoning Cao   +4 more
wiley   +1 more source

Centaurea lycaonica Extracts Induce Apoptosis in HeLa Human Cervical Cancer Cells via Bax/Bcl‐2 Modulation and Caspase Activation: An LC‐HRMS‐Based Study

Food Science &Nutrition, Volume 13, Issue 7, July 2025.
This study highlights the pharmacological mechanisms of dichloromethane (CHD) and methanol (CHM) extracts of Centaurea lycaonica Boiss. & Heldr. herba as the induction of apoptosis on HeLa cells. Apoptotic properties of CHD and CHM are through suppression of Bcl‐2 and increase in Bax, caspase 9, and 3 activities on HeLa cells.
Ayşe Kübra Karaboğa Arslan, Safa Eminoğlu, Leyla Paşayeva, Nuh Mehmet Bozkurt, Osman Tugay   +4 more
wiley   +1 more source

Computational screening combined with well-tempered metadynamics simulations identifies potential TMPRSS2 inhibitors

Scientific Reports
Type-II transmembrane serine proteases are effective pharmacological targets for host defence against viral entry and in certain cancer cell progressions.
C. S. Sharanya, D. Sasikala Wilbee, Shijulal Nelson Sathi, Kathiresan Natarajan   +3 more
doaj   +1 more source