Results 101 to 110 of about 5,406 (212)
Given the lack of knowledge on the rhoptry proteins of Cryptosporidium parvum, we searched for putative members of this protein class in the CryptoDB database using as queries known Toxoplasma gondii rhoptry molecules. We cloned a C.
Cherchi S +5 more
core +1 more source
A Member of the Ferlin Calcium Sensor Family Is Essential for
Invasion of host cells by apicomplexan parasites such as Toxoplasma gondii is critical for their infectivity and pathogenesis. In Toxoplasma, secretion of essential egress, motility, and invasion-related proteins from microneme organelles is regulated by
Bradley I. Coleman +7 more
doaj +1 more source
GFP-PfRab1A fluorescence in late schizonts is associated with rhoptry markers.
Rhoptry markers Rap1 and Ron4 are found in trophozoites and schizonts as discrete foci that colocalize with GFP-PfRab1A fluorescence in late schizonts, but not in earlier phases of parasite development.
Wesley Webster (3162885) +4 more
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A druggable secretory protein maturase of Toxoplasma essential for invasion and egress
Micronemes and rhoptries are specialized secretory organelles that deploy their contents at the apical tip of apicomplexan parasites in a regulated manner.
Sunil Kumar Dogga +8 more
doaj +1 more source
A novel rhoptry protein in Toxoplasma gondii bradyzoites and merozoites
The secretory organelles of Toxoplasma gondii orchestrate invasion of the host cell and establish the parasitophorous vacuole. Although much has been learned about the roles played by these organelles in invasion by the tachyzoite stage, little is known about the contents or functions of these organelles during bradyzoite development or pathogenesis ...
Schwarz, J +4 more
openaire +2 more sources
Invasive forms of apicomplexan parasites contain secretory organelles (which may include micronemes, rhoptries or dense granules), the contents of which mediate invasion of host cells. Only few rhoptry proteins have been identified in <i>Plasmodium&
Janse, C.J. +5 more
core +1 more source
Positioning and function of rhoptry organelles in Toxoplasma gondii
Rhoptries are regulated secretory organelles forming part of the apical complex that defines the phylum of Apicomplexa. The discharge of their content crucially contributes to invasion and to the establishment of an intracellular lifestyle. The Armadillo
Mueller, Christina
core +1 more source
Investigating Rhoptry Gene Conservation between Plasmodium yoelii and Plasmodium falciparum using the Polymerase Chain Reaction for DNA Amplification [PDF]
In order to obtain a tangible basis for vaccine targets, it is crucial to understand the role of proteins at the site of invasion. In previous study, 27 novel rhoptry proteins were identified by MudPIT analysis and immunoelectron microscopy.
Burkhalter, Brooke
core
Apicomplexan parasites are characterised by the presence of specialised organelles, such as rhoptries, located at the apical end of invasive forms that play an important role in invasion of the host cell and formation of the parasitophorous vacuole.
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Disruption of RAMA leads to defective rhoptry morphology and reduced rhoptry neck formation.
Tightly synchronised mature schizonts from DMSO- or RAP-treated cultures of RAMAloxP clone 9C10 parasites were fixed and processed for TEM, then three sections from each sample taken and 20 schizonts examined per section.
Matthew R. G. Russell (7354883) +6 more
core +1 more source

