Results 71 to 80 of about 69,829 (275)

SYNERGY IN MIXED RIBAVERIN-INTERFERON AQUEOS SOLUTIONS

Сеченовский вестник, 2017
Spectrophotometric method of ribavirin determination in aqueous solutions was improved. Feasibility of ribavirin determination in the presence of protein was confirmed.
K. Kienskaya, E. Ilyushenko, I. Belova, M. V. Sardushkin, N. Guznova, V. Piskunova, A. Dremuk, R. Ibragimova, A. V. Kukharenko   +8 more
doaj  

Ribavirin Induces Polyamine Depletion via Nucleotide Depletion to Limit Virus Replication

Cell Reports, 2019
Summary: Common antivirals include nucleoside or nucleotide analogs with base prodrugs. The antiviral ribavirin, a US Food and Drug Administration (FDA)-approved nucleoside antimetabolite, halts guanine production, mutagenizes viral genomes, and ...
Patrick M. Tate, Vincent Mastrodomenico, Bryan C. Mounce   +2 more
doaj   +1 more source

RNA Epigenetics in Cancer: Current Knowledge and Therapeutic Implications

MedComm, Volume 6, Issue 8, August 2025.
RNA epigenetics regulates cancer through RNA modifications, splicing, transport, and translation. Key components include m⁶A writers, splicing factors, RBPs, and nuclear export machinery. Aberrant RNA metabolism drives tumor progression and immune evasion.
Shanhe Huang, Zonglin Li, Weilong Lin, Ruihui Xie, Hai Huang   +4 more
wiley   +1 more source

Evaluation of the potential of a new ribavirin analog impairing the dissemination of ovarian cancer cells.

PLoS ONE, 2019
Epithelial ovarian cancers are insidious pathologies that give a poor prognosis due to their late discovery and the increasing emergence of chemoresistance. Development of small pharmacological anticancer molecules remains a major challenge.
Anaïs Wambecke, Carine Laurent-Issartel, Johanne Leroy-Dudal, Florence Giffard, Fanny Cosson, Nadège Lubin-Germain, Jacques Uziel, Sabrina Kellouche, Franck Carreiras   +8 more
doaj   +1 more source

Favipiravir and Ribavirin Inhibit Replication of Asian and African Strains of Zika Virus in Different Cell Models

Viruses, 2018
Zika virus (ZIKV) has recently emerged as a new public health threat. ZIKV infections have caused a wide spectrum of neurological diseases, such as Guillain–Barré syndrome, myelitis, meningoencephalitis, and congenital microcephaly.
Ji-Ae Kim, Rak-Kyun Seong, Mukesh Kumar, O. S. Shin   +3 more
semanticscholar   +1 more source

A phase IIb single‐center study to assess the efficacy of apremilast for the treatment of nummular eczema

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 8, Page 959-965, August 2025.
Summary Background The pathogenesis of nummular eczema (NE) remains unclear, and no targeted therapy has been approved. Apremilast is a small molecule inhibitor targeting phosphodiesterase‐4. Patients and Methods A phase IIb randomized, double‐blind, placebo‐controlled study evaluating the effects of apremilast or placebo in patients with NE.
Alexander Böhner, Peter Seiringer, Viktoria Kleeberger, Danielle Rogner, Christian Oesterlin, Tilo Biedermann, Kilian Eyerich, Felix Lauffer   +7 more
wiley   +1 more source

Fabrication and evaluation of ribavirin-loaded electrospun nanofibers as an antimicrobial wound dressing

Saudi Pharmaceutical Journal
Background: Skin is regarded as an essential first line of defense against harmful pathogens and it hosts an ecosystem of microorganisms that create a widely diverse skin microbiome.
Khulud A. Alsulami, Abrar A. Bakr, Abdullah A. Alshehri, Alhassan H. Aodah, Fahad A. Almughem, Ali A. Alamer, Lujain A. Alharbi, Deema S. Alsuwayeh, Abdulrahman A. Halwani, Abdullah A. Alamoudi, Haya A. Alfassam, Essam A. Tawfik   +11 more
doaj   +1 more source

Monozentrische Phase‐IIb‐Studie zur Wirksamkeit von Apremilast beim nummulärem Ekzem

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 8, Page 959-966, August 2025.
Zusammenfassung Hintergrund Über die Pathogenese des nummulären Ekzems (NE) ist wenig bekannt und es gibt keine zugelassene zielgerichtete Therapie. Apremilast ist ein Phosphodiesterase‐4‐Inhibitor. Patienten und Methodik Eine randomisierte, doppelblinde, placebokontrollierte Phase‐IIb‐Studie zur Bewertung der Wirkung von Apremilast bei Patienten mit ...
Alexander Böhner, Peter Seiringer, Viktoria Lang, Danielle Rogner, Christian Oesterlin, Tilo Biedermann, Kilian Eyerich, Felix Lauffer   +7 more
wiley   +1 more source

Torque teno virus as a marker of immune status in immunocompromised patients: A systematic review

European Journal of Clinical Investigation, Volume 55, Issue 8, August 2025.
Abstract Background Torque teno virus (TTV) is not known to cause disease in humans; however, chronic inflammatory conditions and immunosuppression states can favour TTV replication. This study aimed to verify the effectiveness of TTV as an immune biomarker.
Janaina B. Medina, Fábio França Vieira e Silva, Rafael Antônio Velôso Caixeta, Bruna de Oliveira Rech, Alba Perez‐Jardón, María Elena Padín‐Iruegas, Mario Pérez‐Sayáns, Paulo Henrique Braz‐Silva, Karem L. Ortega   +8 more
wiley   +1 more source

Ribavirin therapy for Chikungunya arthritis

Journal of Infection in Developing Countries, 2008
Chikungunya is an acute viral infection presenting with a febrile episode and severe arthralgia, swelling of soft tissues, especially around the ankles. Many patients recover with nonspecific treatment of analgesics. Some patients continue to have subacute crippling arthritis in the legs affecting their mobility.
Rajan Ravichandran, Manju Manian
openaire   +4 more sources