Results 71 to 80 of about 61,737 (200)

Fabrication and evaluation of ribavirin-loaded electrospun nanofibers as an antimicrobial wound dressing

Saudi Pharmaceutical Journal
Background: Skin is regarded as an essential first line of defense against harmful pathogens and it hosts an ecosystem of microorganisms that create a widely diverse skin microbiome.
Khulud A. Alsulami, Abrar A. Bakr, Abdullah A. Alshehri, Alhassan H. Aodah, Fahad A. Almughem, Ali A. Alamer, Lujain A. Alharbi, Deema S. Alsuwayeh, Abdulrahman A. Halwani, Abdullah A. Alamoudi, Haya A. Alfassam, Essam A. Tawfik   +11 more
doaj   +1 more source

Efficacy and safety of sofosbuvir–velpatasvir with or without ribavirin in HCV-infected Japanese patients with decompensated cirrhosis: an open-label phase 3 trial

Journal of gastroenterology, 2018
BackgroundIn Japan, hepatitis C virus (HCV)-infected patients with decompensated cirrhosis currently have no treatment options. In this Phase 3 study, we evaluated sofosbuvir–velpatasvir with or without ribavirin for 12 weeks in patients with any HCV ...
T. Takehara, N. Sakamoto, S. Nishiguchi, F. Ikeda, T. Tatsumi, Y. Ueno, H. Yatsuhashi, Y. Takikawa, T. Kanda, M. Sakamoto, A. Tamori, E. Mita, K. Chayama, Gulan Zhang, S. De‐oertel, H. Dvory‐Sobol, Takuma Matsuda, L. Stamm, D. Brainard, Yasuhito Tanaka, M. Kurosaki   +20 more
semanticscholar   +1 more source

Are Tetrapleura tetraptera Phytochemicals Druggable Against SARS‐CoV‐2 Papain‐Like Protein? A Computational Approach

New Zealand Journal of Botany, Volume 64, Issue 1, March 2026.
SARS‐CoV2 Omicron and its substrains are still a critical global health issue and extremely contagious, even with widespread vaccination efforts. Hospitalizations and mortality rates linked to these variants are still prevalent. Current therapeutic options face challenges, including low effectiveness, suboptimal pharmacokinetics, and drug resistance ...
Frank Eric Tatsing Foka, Hazel Tumelo Mufhandu   +1 more
wiley   +1 more source

Ribavirin as a beneficial treatment option for hepatitis C virusassociated glomerular disease

Saudi Journal of Kidney Diseases and Transplantation, 2020
The management of hepatitis C virus (HCV)-induced glomerular disease remains unsatisfactory despite novel advances in antiviral and immunosuppressive therapy.
Fabrizio Fabrizi, Donata Cresseri, Gabriella Moroni, Patrizia Passerini, Francesco Pallotti, Francesca Maria Donato, Pietro Lampertico, Piergiorgio Messa   +7 more
doaj   +1 more source

Populations at Risk for Severe or Complicated Rhinovirus Illness: A Systematic Review and Meta‐Analysis

Influenza and Other Respiratory Viruses, Volume 20, Issue 3, March 2026.
ABSTRACT Background Although most rhinovirus infections are mild and subside quickly, vulnerable populations may experience severe illness. Identifying populations at risk for severe or complicated rhinovirus illness can strengthen the ongoing search for preventative and therapeutic treatments.
David Gou, Jessica Bartoszko, Laura Weiler, Asal Alavi Parsi, Ante Cuvalo, Sahith Rajkumar, Dominik Mertz, Mark Loeb   +7 more
wiley   +1 more source

Synchronous Telemedicine Versus In‐Person Care in Hepatitis C Treatment: A Systematic Review and Meta‐Analysis

Journal of Viral Hepatitis, Volume 33, Issue 3, March 2026.
ABSTRACT Inequitable access to HCV treatment persists, particularly for rural and marginalised populations. Synchronous telemedicine (TM) could mitigate access barriers, but its comparative effectiveness versus in‐person care is uncertain. We performed a systematic review and meta‐analysis comparing synchronous TM with in‐person care for HCV.
Igor Boechat Silveira, Gustavo Procópio Silva, Arthur Victor de Holanda Sampaio, Milena Ramos Tomé, Jingying Elena Chen, Alana Vitória Santos de Jesus, Guilherme Grossi Lopes Cançado   +6 more
wiley   +1 more source

Repurposing of Ribavirin as an Adjunct Therapy against Invasive Candida Strains in an In Vitro Study

Antimicrobial Agents and Chemotherapy, 2019
The use of antifungal agents in clinical settings is limited by the appearance of drug resistance and adverse side effects. There is, therefore, an urgent need to develop new drugs to strengthen the treatment of invasive fungal diseases.
H. Yousfi, C. Cassagne, S. Ranque, J. Rolain, F. Bittar   +4 more
semanticscholar   +1 more source

Real‐World Impact of a Simplified ‘Test and Treat’ Strategy for In‐Hospital HCV Micro‐Elimination

Journal of Viral Hepatitis, Volume 33, Issue 3, March 2026.
ABSTRACT Hepatitis C virus (HCV) micro‐elimination faces challenges from fragmented care pathways, particularly in high‐prevalence regions with complex genotypes and socioeconomic barriers. This study evaluated a simplified ‘Test and Treat’ (TNT) strategy to enhance in‐hospital HCV micro‐elimination by reducing delays and improving linkage to care ...
Chunfang You, Yuting Diao, Juan Tang, Jing Tang, Wei Deng, Chunqi Zheng, Dongxia Liao, Dan Song, Jie Wang, Yangyang Pu   +9 more
wiley   +1 more source

Roles of ITPA and IL28B Genotypes in Chronic Hepatitis C Patients Treated with Peginterferon Plus Ribavirin

Viruses, 2012
It has been reported that inosine triphosphatase (ITPA) gene variants protect against ribavirin-induced anemia in patients treated for chronic hepatitis C.
Osamu Yokosuka, Fumio Imazeki, Makoto Arai, Keiichi Fujiwara, Xia Jiang, Shuang Wu, Shingo Nakamoto, Tatsuo Kanda, Tatsuo Miyamura   +8 more
doaj   +1 more source

Favipiravir and Ribavirin Inhibit Replication of Asian and African Strains of Zika Virus in Different Cell Models

Viruses, 2018
Zika virus (ZIKV) has recently emerged as a new public health threat. ZIKV infections have caused a wide spectrum of neurological diseases, such as Guillain–Barré syndrome, myelitis, meningoencephalitis, and congenital microcephaly.
Ji-Ae Kim, Rak-Kyun Seong, Mukesh Kumar, O. S. Shin   +3 more
semanticscholar   +1 more source