Results 71 to 80 of about 77,609 (253)

Ribavirin exerts differential effects on functions of Cd4+ Th1, Th2, and regulatory T cell clones in hepatitis C. [PDF]

PLoS ONE, 2012
Ribavirin improves outcomes of therapy in chronic hepatitis C but its mode of action has still remained unclear. Since ribavirin has been proposed to modulate the host's T cell responses, we studied its direct effects on CD4(+) T cell clones with diverse
Bettina Langhans, Hans Dieter Nischalke, Simone Arndt, Ingrid Braunschweiger, Jacob Nattermann, Tilman Sauerbruch, Ulrich Spengler   +6 more
doaj   +1 more source

Cryoglobulinemia: An update on classification, pathophysiology, clinical presentation, and management

Journal of Internal Medicine, Volume 299, Issue 2, Page 196-215, February 2026.
Abstract Cryoglobulinemia (CG) is defined by the presence of serum immunoglobulins that precipitate below 37°C and redissolve upon rewarming. It is classified into three types based on immunoglobulin composition. Type I, a rare form, involves monoclonal IgM or IgG and is linked to lymphoproliferative disorders.
Anna Linda Zignego, Laura Gragnani, Marcella Visentini, Riccardo Bomben, Luca Arcaini, Clodoveo Ferri, Valter Gattei, Cesare Mazzaro   +7 more
wiley   +1 more source

Is increased hepatitis C virus case-finding combined with current or 8-week to 12-week direct-acting antiviral therapy cost-effective in UK prisons? A prevention benefit analysis [PDF]

, 2016
UNLABELLED: Prisoners have a high prevalence of hepatitis C virus (HCV), but case-finding may not have been cost-effective because treatment often exceeded average prison stay combined with a lack of continuity of care. We assessed the cost-effectiveness
Brew, Iain F., Hickman, Mathew, Hutchinson, Sharon J., Irving, William L., Mandal, Sema, Martin, Natasha K., Miners, Alec, O'Moore, Eamonn, Saksena, Sushma, Vickerman, Peter, Williamson, Joan   +10 more
core   +3 more sources

Bee products as alternatives in the treatment of viral infections

Journal of the Science of Food and Agriculture, Volume 106, Issue 1, Page 33-54, 15 January 2026.
Abstract Medicines used in the treatment of viral infections usually reduce symptoms. There is a need to develop drugs that inhibit the viruses and do not merely relieve the symptoms. Natural bee products possess many pharmacological properties and are widely used in folk medicine. There are many studies on the antibacterial effects of bee products but
Michał Otręba, Łukasz Marek, Jerzy Stojko, Anna Rzepecka‐Stojko   +3 more
wiley   +1 more source

Orthotopic liver transplantation in human-immunodeficiency-virus-positive patients in Germany [PDF]

, 2012
Objectives: This summary evaluates the outcomes of orthotopic liver transplantation (OLT) of HIV-positive patients in Germany. Methods: Retrospective chart analysis of HIV-positive patients, who had been liver-transplanted in Germany between July ...
Anadol, Evrim, Beckebaum, Susanne, Berg, C., Bickel, Markus, Ganten, Tom M., Hitzenbichler, Florian, Kalff, Jörg C., Kittner, Jens Martin, Manekeller, Steffen, Paul, Andreas, Radecke, Klaus, Rockstroh, Jürgen, Sauerbruch, Tilman, Spengler, Ulrich, Stoll, Matthias, Zoufaly, Alexander   +15 more
core   +2 more sources

SYNERGY IN MIXED RIBAVERIN-INTERFERON AQUEOS SOLUTIONS

Сеченовский вестник, 2017
Spectrophotometric method of ribavirin determination in aqueous solutions was improved. Feasibility of ribavirin determination in the presence of protein was confirmed.
K. Kienskaya, E. Ilyushenko, I. Belova, M. V. Sardushkin, N. Guznova, V. Piskunova, A. Dremuk, R. Ibragimova, A. V. Kukharenko   +8 more
doaj  

Ribavirin Induces Polyamine Depletion via Nucleotide Depletion to Limit Virus Replication

Cell Reports, 2019
Summary: Common antivirals include nucleoside or nucleotide analogs with base prodrugs. The antiviral ribavirin, a US Food and Drug Administration (FDA)-approved nucleoside antimetabolite, halts guanine production, mutagenizes viral genomes, and ...
Patrick M. Tate, Vincent Mastrodomenico, Bryan C. Mounce   +2 more
doaj   +1 more source

European Code Against Cancer, 5th edition – cancer‐causing infections and related interventions

Molecular Oncology, Volume 20, Issue 1, Page 96-116, January 2026.
The 5th edition of the European Code Against Cancer (ECAC5) contains 14 recommendations on cancer prevention. Here, we update the cancer prevention recommendations related to cancer‐causing infections, namely H. pylori, HPV, HBV, HCV and HIV, positioned as recommendation number 12.
Catharina Johanna Alberts, Paul Bloem, Silvia de Sanjosé, Sophie Grabar, Marcis Leja, Peter Malfertheiner, Mojca Matičič, Francis Mégraud, Francesco Negro, Martyn Plummer, Maarten Schim van der Loeff, Graciela Balbín, Josefina Salazar, Hajo Zeeb, Ariadna Feliu, Erica D'Souza, David Ritchie, Carolina Espina, Silvia Franceschi   +18 more
wiley   +1 more source

Evaluation of the potential of a new ribavirin analog impairing the dissemination of ovarian cancer cells.

PLoS ONE, 2019
Epithelial ovarian cancers are insidious pathologies that give a poor prognosis due to their late discovery and the increasing emergence of chemoresistance. Development of small pharmacological anticancer molecules remains a major challenge.
Anaïs Wambecke, Carine Laurent-Issartel, Johanne Leroy-Dudal, Florence Giffard, Fanny Cosson, Nadège Lubin-Germain, Jacques Uziel, Sabrina Kellouche, Franck Carreiras   +8 more
doaj   +1 more source

Association of IL28B Polymorphisms With Hepatitis C Susceptibility in Southern Iran's β‐Thalassemia Population: A Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background and Aims Thalassemia is a hereditary hematological condition which interferes with the production of hemoglobin (Hb). Patients with thalassemia require regular blood transfusion, which makes them highly susceptible to pathogens, and especially viral pathogens.
Fatemeh Askari, Masoud Kargar, Zeinab Deris Zayeri, Mohammad Ali Jalalifar, Bijan Keikhaei, Gholam Abbas Kaydani   +5 more
wiley   +1 more source