Results 151 to 160 of about 16,252 (205)

Evaluation of RNA extraction and rRNA depletion protocols for RNA-Seq in eleven edible seaweed species from brown, red, and green algae.

open access: yesPLoS ONE
Seaweeds represent a promising resource for food as well as pharmaceutical and cosmetic applications. However, genomic and transcriptomic research on these organisms remains underdeveloped, partly due to technical challenges in DNA/RNA extraction and ...
Rob J Dekker   +6 more
doaj   +1 more source

Mutant NPM1 marginally impacts ribosome footprint in acute myeloid leukemia cells

open access: yeseJHaem
Background NPM1‐mutated acute myeloid leukemia (AML) is the most frequent AML subtype. As wild‐type NPM1 is known to orchestrate ribosome biogenesis, it has been hypothesized that altered translation may contribute to leukemogenesis and leukemia ...
Lorenzo Brunetti   +4 more
doaj   +1 more source

Genome-wide analysis reveals transcriptional and translational changes during diapause of the Asian corn borer (Ostrinia furnacalis)

open access: yesBMC Biology
Background Diapause, a pivotal phase in the insect life cycle, enables survival during harsh environmental conditions. Unraveling the gene expression profiles of the diapause process helps uncover the molecular mechanisms that underlying diapause, which ...
Xingzhuo Yang   +3 more
doaj   +1 more source

Sequence grammar and dynamics of subcellular translation revealed by APEX-Ribo-Seq

open access: yes
AbstractLocal translation at specific subcellular regions is proposed to define appropriate protein destinations and functions. However, our understanding of local translation is still far from complete, due to a lack of versatile analysis tools. Here, we developed a new method, termed “APEX-Ribo-Seq”, that integrates ribosome profiling (Ribo-Seq) with
Kotaro Tomuro   +7 more
openaire   +1 more source

ggRibo: a ggplot-based single-gene viewer for visualizing Ribo-seq and related omics datasets

open access: yes
ABSTRACTVisualizing periodic Ribo-seq data within genes of interest is a powerful approach to studying mRNA translation, but its application is limited by a lack of robust tools. Here, we introduceggRibo, a user-friendly R package for visualizing individual gene expression, integrating Ribo-seq, RNA-seq, and other genome-wide datasets with flexible ...
Hsin-Yen Larry Wu   +2 more
openaire   +2 more sources

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