Seaweeds represent a promising resource for food as well as pharmaceutical and cosmetic applications. However, genomic and transcriptomic research on these organisms remains underdeveloped, partly due to technical challenges in DNA/RNA extraction and ...
Rob J Dekker +6 more
doaj +1 more source
Mutant NPM1 marginally impacts ribosome footprint in acute myeloid leukemia cells
Background NPM1‐mutated acute myeloid leukemia (AML) is the most frequent AML subtype. As wild‐type NPM1 is known to orchestrate ribosome biogenesis, it has been hypothesized that altered translation may contribute to leukemogenesis and leukemia ...
Lorenzo Brunetti +4 more
doaj +1 more source
Background Diapause, a pivotal phase in the insect life cycle, enables survival during harsh environmental conditions. Unraveling the gene expression profiles of the diapause process helps uncover the molecular mechanisms that underlying diapause, which ...
Xingzhuo Yang +3 more
doaj +1 more source
Optimization of Ribosome Footprinting Conditions for Ribo-Seq in Human and <i>Drosophila melanogaster</i> Tissue Culture Cells. [PDF]
Douka K, Agapiou M, Birds I, Aspden JL.
europepmc +1 more source
Sequence grammar and dynamics of subcellular translation revealed by APEX-Ribo-Seq
AbstractLocal translation at specific subcellular regions is proposed to define appropriate protein destinations and functions. However, our understanding of local translation is still far from complete, due to a lack of versatile analysis tools. Here, we developed a new method, termed “APEX-Ribo-Seq”, that integrates ribosome profiling (Ribo-Seq) with
Kotaro Tomuro +7 more
openaire +1 more source
p53 induces transcriptional and translational programs to suppress cell proliferation and growth [PDF]
core +1 more source
How tailored Ribo-seq methods probe unique translation events. [PDF]
Marks J, Meydan S.
europepmc +1 more source
ggRibo: a ggplot-based single-gene viewer for visualizing Ribo-seq and related omics datasets
ABSTRACTVisualizing periodic Ribo-seq data within genes of interest is a powerful approach to studying mRNA translation, but its application is limited by a lack of robust tools. Here, we introduceggRibo, a user-friendly R package for visualizing individual gene expression, integrating Ribo-seq, RNA-seq, and other genome-wide datasets with flexible ...
Hsin-Yen Larry Wu +2 more
openaire +2 more sources
InspectorORF: a tool for visualizing Ribo-Seq and additional genomic or transcriptomic data. [PDF]
Ward EL +4 more
europepmc +1 more source
Data-driven design of LNA-blockers for efficient contaminant removal in Ribo-Seq libraries. [PDF]
Ricciardi DA, Peter FE, Böhmer M.
europepmc +1 more source

