Results 1 to 10 of about 5,654 (195)

Polysome profiling in liver identifies dynamic regulation of endoplasmic reticulum translatome by obesity and fasting. [PDF]

open access: yesPLoS Genetics, 2012
Obesity-associated metabolic complications are generally considered to emerge from abnormalities in carbohydrate and lipid metabolism, whereas the status of protein metabolism is not well studied.
Suneng Fu   +6 more
doaj   +5 more sources

Adaptive laboratory evolution of a genome-reduced Escherichia coli [PDF]

open access: yesNature Communications, 2019
Genome-reduced bacteria often show impaired growth under laboratory conditions. Here the authors use adaptive laboratory evolution to optimise growth performance and show transcriptome and translatome-wide remodeling of the organism.
Donghui Choe   +8 more
doaj   +3 more sources

Translatome of dorsal striatum parvalbumin interneurons revisited: insights across diverse experimental paradigms [PDF]

open access: yesFrontiers in Cellular Neuroscience
Parvalbumin (PV) interneurons in the dorsal striatum (DS) are fast-spiking GABAergic cells critical for feedforward inhibition and synaptic integration within basal ganglia circuits.
Claire Naon   +18 more
doaj   +2 more sources

Citrus phloem specific transcriptional profiling through the development of a citrus tristeza virus expressed translating ribosome affinity purification system [PDF]

open access: yesPlant Methods
Background The analysis of translationally active mRNAs, or translatome, is a useful approach for monitoring cellular and plant physiological responses.
James N. Culver   +9 more
doaj   +2 more sources

Delayed Protein Changes During Seed Germination

open access: yesFrontiers in Plant Science, 2021
Over the past decade, ample transcriptome data have been generated at different stages during seed germination; however, far less is known about protein synthesis during this important physiological process.
Bing Bai   +9 more
doaj   +1 more source

A translatome-transcriptome multi-omics gene regulatory network reveals the complicated functional landscape of maize

open access: yesGenome Biology, 2023
Background Maize (Zea mays L.) is one of the most important crops worldwide. Although sophisticated maize gene regulatory networks (GRNs) have been constructed for functional genomics and phenotypic dissection, a multi-omics GRN connecting the ...
Wanchao Zhu   +10 more
doaj   +1 more source

Dynamic patterns of the translatome in a hybrid triplet show translational fractionation of the maize subgenomes

open access: yesCrop Journal, 2022
Heterosis, the phenomenon in which hybrids outperform their parents, has been utilized in maize (Zea mays L.) for over 100 years. To provide a more complete understanding of heterosis, we collected a comprehensive transcriptome and translatome dataset on
Wanchao Zhu   +7 more
doaj   +1 more source

Differential Regulation of the Ribosomal Association of mRNA Transcripts in an Arabidopsis Mutant Defective in Jasmonate-Dependent Wound Response

open access: yesFrontiers in Plant Science, 2021
Jasmonoyl-L-isoleucine (JA-Ile) is a powerful oxylipin responsible for the genome-wide transcriptional reprogramming in plants that results in major physiological shifts from growth to defense.
Athen Kimberlin   +5 more
doaj   +1 more source

Preferential Ribosome Loading on the Stress-Upregulated mRNA Pool Shapes the Selective Translation under Stress Conditions

open access: yesPlants, 2021
The reprogramming of gene expression is one of the key responses to environmental stimuli, whereas changes in mRNA do not necessarily bring forth corresponding changes of the protein, which seems partially due to the stress-induced selective translation.
Yan Chen, Min Liu, Zhicheng Dong
doaj   +1 more source

Trap-TRAP, a Versatile Tool for Tissue-Specific Translatomics in Zebrafish

open access: yesFrontiers in Cell and Developmental Biology, 2022
Developmental and physiological processes depend on the transcriptional and translational activity of heterogeneous cell populations. A main challenge in gene expression studies is dealing with this intrinsic complexity while keeping sequencing ...
Jorge Corbacho   +4 more
doaj   +1 more source

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