Results 11 to 20 of about 4,258 (187)

Stress-dependent coordination of transcriptome and translatome in yeast. [PDF]

PLoS Biology, 2009
Cells rapidly alter gene expression in response to environmental stimuli such as nutrients, hormones, and drugs. During the imposed "remodeling" of gene expression, changes in the levels of particular mRNAs do not necessarily correlate with those of the ...
Regula E Halbeisen, André P Gerber
doaj   +11 more sources

A translatome-transcriptome multi-omics gene regulatory network reveals the complicated functional landscape of maize

Genome Biology, 2023
Background Maize (Zea mays L.) is one of the most important crops worldwide. Although sophisticated maize gene regulatory networks (GRNs) have been constructed for functional genomics and phenotypic dissection, a multi-omics GRN connecting the ...
Wanchao Zhu, Xinxin Miao, Jia Qian, Sijia Chen, Qixiao Jin, Mingzhu Li, Linqian Han, Wanshun Zhong, Dan Xie, Xiaoyang Shang, Lin Li   +10 more
doaj   +2 more sources

Widespread uncoupling between transcriptome and translatome variations after a stimulus in mammalian cells [PDF]

BMC Genomics, 2012
Background The classical view on eukaryotic gene expression proposes the scheme of a forward flow for which fluctuations in mRNA levels upon a stimulus contribute to determine variations in mRNA availability for translation. Here we address this issue by
Tebaldi Toma, Re Angela, Viero Gabriella, Pegoretti Ilaria, Passerini Andrea, Blanzieri Enrico, Quattrone Alessandro   +6 more
doaj   +2 more sources

A high-resolution temporal atlas of the SARS-CoV-2 translatome and transcriptome

Nature Communications, 2021
Here, Kim et al. apply various sequencing techniques (RPF-seq, QTI-seq, mRNA-seq, sRNA-seq) to unravel the high-resolution, longitudinal translatome and transcriptome of SARS-CoV-2.
Doyeon Kim, Sukjun Kim, Joori Park, Hee Ryung Chang, Jeeyoon Chang, Junhak Ahn, Heedo Park, Junehee Park, Narae Son, Gihyeon Kang, Jeonghun Kim, Kisoon Kim, Man-Seong Park, Yoon Ki Kim, Daehyun Baek   +14 more
doaj   +2 more sources

Transcriptome and translatome co-evolution in mammals [PDF]

Nature, 2020
Gene-expression programs define shared and species-specific phenotypes, but their evolution remains largely uncharacterized beyond the transcriptome layer.
Margarida Cardoso-Moreira, Antoine H. F. M. Peters, Leushkin, Evgeny, Brüning, Thoomke, Mößinger, K., Mößinger, Katharina, Henrik Kaessmann, Janich, Peggy, Gill, Mark E, Zhong-Yi Wang, Leushkin, E., Peters, Antoine H F M, Grützner, F., Boubou Diagouraga, Janich, P., David Gatfield, Brüning, T., Angélica Liechti, Wang, Z.Y., Peggy Janich, Ovchinnikova, S., Thoomke Brüning, Liechti, Angélica, Ovchinnikova, Svetlana, Anders, S., Peters, Antoine, de Massy, B., Wang, Zhong-Yi, Diagouraga, Boubou, Anders, Simon, Gill, M.E., Katharina Mößinger, Diagouraga, B., Simon Anders, Evgeny Leushkin, Gatfield, D., de Massy, Bernard, Cardoso-Moreira, Margarida, Rummel, Coralie, Gatfield, David, Bernard de Massy, Kaessmann, H., Coralie Rummel, Cardoso-Moreira, M., Svetlana Ovchinnikova, Liechti, A., Kaessmann, Henrik, Gill, Mark, Mark E. Gill, Peters, A.H.F.M., Grützner, Frank, Rummel, C., Frank Grützner   +52 more
core   +5 more sources

Legume-rhizobia symbiosis: Translatome analysis [PDF]

Genetics and Molecular Biology
Leguminous plants can establish endosymbiotic relationships with nitrogen-fixing soil rhizobacteria. Bacterial infection and nodule organogenesis are two independent but highly coordinated genetic programs that are active during this interaction.
María Martha Sainz, Mariana Sotelo-Silveira, Carla V. Filippi, Sofía Zardo   +3 more
doaj   +3 more sources

Data on translatome analysis of Mycoplasma gallisepticum [PDF]

Data in Brief, 2016
Mycoplasma gallisepticum is a bacterium of class Mollicutes which encompasses wall-less bacteria with significantly reduced genomes. Due to their overall reduction and simplicity mycoplasmas serve as a model of minimal cell and are used for systems ...
Fisunov, G.Y., V.M. Govorun, Govorun, V.M., Evsyutina, D.V., D.V. Evsyutina, G.Y. Fisunov   +5 more
core   +4 more sources

Effects of kasugamycin on the translatome of Escherichia coli [PDF]

PLOS ONE, 2017
It is long known that Kasugamycin inhibits translation of canonical transcripts containing a 5’-UTR with a Shine Dalgarno (SD) motif, but not that of leaderless transcripts.
Jens Schweitzer (3637075), Lange, Christian, Lehr, Matthias, Zerulla, Karolin, Tino Polen (3637078), Karolin Zerulla, Polen, Tino, Wendisch, Volker F. ; https://orcid.org/, Volker F Wendisch, Soppa, Jörg, Matthias Lehr, Christian Lange, Jörg Soppa (23130), Ludwig, Petra, Wendisch, Volker F., Jörg Soppa, Petra Ludwig, Ludwig, Pete, Schweitzer, Jens, Jens Schweitzer, Volker F. Wendisch (1739545), Christian Lange (70151), Karolin Zerulla (231235), Petra Ludwig (3637081), Matthias Lehr (537954), Tino Polen   +25 more
core   +8 more sources

Local translatome sustains synaptic function in impaired Wallerian degeneration

EMBO Reports
After injury, severed axons separated from their somas activate programmed axon degeneration, a conserved pathway to initiate their degeneration within a day.
Maria Paglione, Leonardo Restivo, Sarah Zakhia, Arnau Llobet Rosell, Marco Terenzio, Lukas J Neukomm   +5 more
doaj   +3 more sources

Selective translational usage of TSS and core promoters revealed by translatome sequencing

BMC Genomics, 2019
Background In mammals, fine-tuned regulation of gene expression leads to transcription initiation from diverse transcription start sites (TSSs) and multiple core promoters. Although polysome association is a critical step in translation, whether polysome
Hua Li, Ling Bai, Hongmei Li, Xinhui Li, Yani Kang, Ningbo Zhang, Jielin Sun, Zhifeng Shao   +7 more
doaj   +2 more sources