Results 21 to 30 of about 5,654 (195)
Insights Into Translatomics in the Nervous System [PDF]
Frontiers in Genetics, 2020 Most neurological disorders are caused by abnormal gene translation. Generally, dysregulation of elements involved in the translational process disrupts homeostasis in neurons and neuroglia. Better understanding of how the gene translation process occurs requires detailed analysis of transcriptomic and proteomic profile data.
Shuxia Zhang +6 more
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Evolutionarily divergent mTOR remodels translatome for tissue regeneration [PDF]
Nature, 2023 An outstanding mystery in biology is why some species, such as the axolotl, can regenerate tissues whereas mammals cannot1. Here, we demonstrate that rapid activation of protein synthesis is a unique feature of the injury response critical for limb regeneration in the axolotl (Ambystoma mexicanum).
Olena Zhulyn +8 more
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Selection of Cashmere Fineness Functional Genes by Translatomics [PDF]
Frontiers in Genetics, 2022 Cashmere fineness is an important index to evaluate cashmere quality. Liaoning Cashmere Goat (LCG) has a large cashmere production and long cashmere fiber, but its fineness is not ideal. Therefore, it is important to find genes involved in cashmere fineness that can be used in future endeavors aiming to improve this phenotype.
Yu Zhang +11 more
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Translatomics: The Global View of Translation [PDF]
International Journal of Molecular Sciences, 2019 In all kingdoms of life, proteins are synthesized by ribosomes in a process referred to as translation. The amplitude of translational regulation exceeds the sum of transcription, mRNA degradation and protein degradation. Therefore, it is essential to investigate translation in a global scale.
Jing Zhao +4 more
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Translational Control under Stress: Reshaping the Translatome [PDF]
BioEssays, 2019 Adequate reprogramming of cellular metabolism in response to stresses or suboptimal growth conditions involves a myriad of coordinated changes that serve to promote cell survival. As protein synthesis is an energetically expensive process, its regulation under stress is of critical importance.
Vivek M, Advani, Pavel, Ivanov
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Translational regulation contributes to the elevated CO2 response in two Solanum species. [PDF]
, 2020 Understanding the impact of elevated CO2 (eCO2 ) in global agriculture is important given climate change projections. Breeding climate-resilient crops depends on genetic variation within naturally varying populations.
Brady, Siobhan M +6 more
core +2 more sources
The translatome of neuronal cell bodies, dendrites, and axons [PDF]
Proceedings of the National Academy of Sciences, 2021 Significance Proteins are the key drivers of neuronal synaptic function. The regulation of gene expression is important for the formation and modification of synapses throughout the lifespan. The complexity of dendrites and axons imposes unique challenges for protein supply at remote locations.
Glock, Caspar +7 more
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Lost in Translation: Physiological Roles of Stored mRNAs in Seed Germination
Plants, 2020 Seeds characteristics such as germination ability, dormancy, and storability/longevity are important traits in agriculture, and various genes have been identified that are involved in its regulation at the transcriptional and post-transcriptional level ...
Naoto Sano +2 more
doaj +1 more source
A post-transcriptional regulatory landscape of aging in the female mouse hippocampus
Frontiers in Aging Neuroscience, 2023 Aging is associated with substantial physiological changes and constitutes a major risk factor for neurological disorders including dementia. Alterations in gene expression upon aging have been extensively studied; however, an in-depth characterization ...
Raphaelle Winsky-Sommerer +4 more
doaj +1 more source
Transcriptome and translatome profiles of Streptomyces species in different growth phases. [PDF]
, 2020 Streptomyces are efficient producers of various bioactive compounds, which are mostly synthesized by their secondary metabolite biosynthetic gene clusters (smBGCs).
Cho, Byung-Kwan +6 more
core +1 more source