Results 31 to 40 of about 4,258 (187)
Lost in Translation: Physiological Roles of Stored mRNAs in Seed Germination
Plants, 2020 Seeds characteristics such as germination ability, dormancy, and storability/longevity are important traits in agriculture, and various genes have been identified that are involved in its regulation at the transcriptional and post-transcriptional level ...
Naoto Sano +2 more
doaj +1 more source
A post-transcriptional regulatory landscape of aging in the female mouse hippocampus
Frontiers in Aging Neuroscience, 2023 Aging is associated with substantial physiological changes and constitutes a major risk factor for neurological disorders including dementia. Alterations in gene expression upon aging have been extensively studied; however, an in-depth characterization ...
Raphaelle Winsky-Sommerer +4 more
doaj +1 more source
Antioxidants, 2022 Soybean (Glycine max (L.) Merr.) establishes symbiosis with rhizobacteria, developing the symbiotic nodule, where the biological nitrogen fixation (BNF) occurs.
María Martha Sainz +5 more
doaj +1 more source
A RiboCancer cell line panel reveals that CLL-associated Rps15 mutations translationally rewire transcription through codon-specific tRNA accommodation defects. [PDF]
HemasphereAbstract Recurrent point mutations in ribosomal proteins (RPs) RPL10 and RPS15 are found in T‐cell acute lymphoblastic leukemia (T‐ALL) and chronic lymphocytic leukemia (CLL), respectively. Furthermore, deletions of RPL5, RPL11, and RPL22 are frequent in hematologic diseases such as Diamond Blackfan Anemia, T‐ALL, multiple myeloma, and in a variety of ...
Astier A +26 more
europepmc +2 more sources
Exploring the noncanonical translatome using massively integrated coexpression analysis
, 2023 This is supplementary data files for the publication entitled "Massively integrated coexpression analysis reveals transcriptional regulation, evolution and cellular implications of the noncanonical translatome"
Omer Acar (11938058) +2 more
core +1 more source
Tissue- and stage-specific landscape of the mouse translatome [PDF]
Nucleic Acids Research, 2021 Abstract The current understanding of how overall principles of translational control govern the embryo-to-adult transition in mammals is still far from comprehensive. Herein we profiled the translatomes and transcriptomes of six tissues from the mice at embryonic and adult stages and presented the first report of tissue- and stage ...
Hongwei Wang +10 more
openaire +3 more sources
Pharmaceutics, 2022 The present study aimed to better understand the possibility of utilizing all-trans retinoic acids (ATRA) in acute myeloid leukemia (AML). We found that ATRA significantly suppressed global translation and protein synthesis in AML cells.
Ke Wang +8 more
doaj +1 more source
Translational changes induced by acute sleep deprivation uncovered by TRAP-Seq
Molecular Brain, 2020 Sleep deprivation is a global health problem adversely affecting health as well as causing decrements in learning and performance. Sleep deprivation induces significant changes in gene transcription in many brain regions, with the hippocampus ...
Lisa C. Lyons +4 more
doaj +1 more source
The Plant Translatome Surveyed by Ribosome Profiling [PDF]
Plant and Cell Physiology, 2019 Abstract Although transcriptome changes have long been recognized as a mechanism to induce tentative substitution of expressed genes in diverse biological processes in plants, the regulation of translation—the final step of the central dogma of molecular biology—emerged as an alternative and prominent layer in defining the output of ...
Tomoya Fujita +2 more
openaire +2 more sources
Molecular Mechanisms of Persistence in Protozoan Parasites
Microorganisms, 2023 Protozoan parasites are known for their remarkable capacity to persist within the bodies of vertebrate hosts, which frequently results in prolonged infections and the recurrence of diseases.
Asfiha Tarannum +3 more
doaj +1 more source