Results 51 to 60 of about 5,654 (195)
Data on translatome analysis of Mycoplasma gallisepticum
Data in Brief, 2016 Mycoplasma gallisepticum is a bacterium of class Mollicutes which encompasses wall-less bacteria with significantly reduced genomes. Due to their overall reduction and simplicity mycoplasmas serve as a model of minimal cell and are used for systems biology studies.
G.Y. Fisunov +2 more
openaire +3 more sources
Astonishing advances in mouse genetic tools for biomedical research
Swiss Medical Weekly, 2015 The humble house mouse has long been a workhorse model system in biomedical research. The technology for introducing site-specific genome modifications led to Nobel Prizes for its pioneers and opened a new era of mouse genetics.
Walker Scot Jackson, Lech Kaczmarczyk
doaj +1 more source
The expanding toolkit of translating ribosome affinity purification [PDF]
, 2017 Translating ribosome affinity purification is a method initially developed for profiling mRNA from genetically defined cell types in complex tissues. It has been applied both to identify target molecules in cell types that are important for controlling a
Dougherty, Joseph D
core +2 more sources
tRanslatome: an R/Bioconductor package to portray translational control [PDF]
Bioinformatics, 2013 Abstract Summary: High-throughput technologies have led to an explosion of genomic data available for automated analysis. The consequent possibility to simultaneously sample multiple layers of variation along the gene expression flow requires computational methods integrating raw information from different ‘-omics’.
Tebaldi, Toma +4 more
openaire +4 more sources
Analyzing the Complex Regulatory Landscape of Hfq – an Integrative, Multi-Omics Approach [PDF]
, 2017 The ability of bacteria to respond to environmental change is based on the ability to coordinate, redirect and fine-tune their genetic repertoire as and when required.
Chandra, Govind +5 more
core +1 more source
Transcriptome and translatome comparison of tissues from Arabidopsis thaliana
Scientific Data, 2023 AbstractTranslation is one of the multiple complementary steps that orchestrates gene activity. In contrast to the straightforwardness of transcriptional surveys, genome-wide profiles of the translational landscape of plant cells remain technically challenging and are less well explored.
Isabel Cristina Vélez-Bermúdez +4 more
openaire +3 more sources
HeliyonExposure to anesthesia in early life may cause severe damage to the brain and lead to cognitive impairment. The underlying mechanisms, which have only been investigated in a limited scale, remains largely elusive.
Menghan Wang +3 more
doaj +1 more source
Frontiers in Nutrition, 2021 An excessive high-fat/energy diet is a major cause of obesity and linked complications, such as non-alcoholic fatty liver disease (NAFLD). Betaine has been shown to effectively improve hepatic lipid metabolism.
Tengda Huang +12 more
doaj +1 more source
Axon TRAP reveals learning-associated alterations in cortical axonal mRNAs in the lateral amygdala
eLife, 2019 Local translation can support memory consolidation by supplying new proteins to synapses undergoing plasticity. Translation in adult forebrain dendrites is an established mechanism of synaptic plasticity and is regulated by learning, yet there is no ...
Linnaea E Ostroff +9 more
doaj +1 more source
G Protein-Coupled Receptors As Regulators of Localized Translation: The Forgotten Pathway?
Frontiers in Endocrinology, 2018 G protein-coupled receptors (GPCRs) exert their physiological function by transducing a complex signaling network that coordinates gene expression and dictates the phenotype of highly differentiated cells.
Aurélie Tréfier +23 more
doaj +1 more source