Results 71 to 80 of about 361 (118)

Sex‐ and Region‐Specific Glial Reactivity in Hyperthyroid Mice Lacks Correlation With the Noncognitive and Non‐Depressive‐Like Behavioral Alterations

Brain and Behavior, Volume 16, Issue 6, June 2026.
Hyperthyroidism induces sex‐ and region‐specific glial reactivity without correlation to the noncognitive, non‐depressive behavioral changes in mice. ABSTRACT Background Glial reactivity is implicated in hyperthyroidism‐associated cognitive and psychiatric disorders, yet in vivo imaging evidence of glial reactivity in hyperthyroidism remains to be ...
Qianqian Xue, Zefang Lin, Yaofeng Wang, Xiuting Lin, Yun Yang, Chao Wang, Yuhong Ye, Weibing Miao   +7 more
wiley   +1 more source

Solanesol Alleviates Perfluoroheptanoic Acid‐Induced Premature Senescence in Human Skin Fibroblasts via RNA Methylation

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
Perfluoroheptanoic acid (PFHpA) induces premature senescence in normal human skin fibroblasts (HSFs), as characterized by decreased cell viability, increased SA‐β‐gal staining, impaired wound healing, cell cycle dysregulation, elevated ROS levels, and upregulated SASP mRNA expression.
Jiaqi Fu, Tingting Huang, Guisong Li, Xinyu Zhang, Luyi Tan, Chenyu Zhu, Wenji Zhang, Wenjuan Zhang   +7 more
wiley   +1 more source

Decoding cancer‐associated ribosomal protein mutations: A new frontier in cancer and ribosome biology

HemaSphere, Volume 10, Issue 9, September 2026.
Mirsada Čaušević, Robbie Loewith, Siniša Volarević   +2 more
wiley   +1 more source

Glia Are Bussin’: How Single‐Cell and Spatial Transcriptomics Enlighten the Role of Neuroglia in Spinal Cord Injury and Regeneration

Glia, Volume 74, Issue 6, June 2026.
Neuroglia have been extensively profiled using single‐cell genomics, improving our understanding of their dynamics after spinal cord injury. A meta‐analysis of five single‐cell time‐course genomic studies reveals heterogeneity underscoring important challenges for interpretation.
Julio Mejia, Philip J. Horner
wiley   +1 more source

A translational program that suppresses metabolism to shield the genome

Nature Communications, 2020
Translatome remodelling controls stress-adaptive protein output. Here the authors reveal that in response to stimuli, eIF5A functions as a pH-regulated translation factor that responds to fermentation-induced acidosis affecting cellular metabolism.
Nathan C. Balukoff, J. J. David Ho, Phaedra R. Theodoridis, Miling Wang, Michael Bokros, Lis M. Llanio, Jonathan R. Krieger, Jonathan H. Schatz, Stephen Lee   +8 more
doaj   +1 more source

Functional and molecular heterogeneity of D2R neurons along dorsal ventral axis in the striatum

Nature Communications, 2020
Striatal dopaminoceptive neurons are molecularly and functionally heterogeneous. Here, the authors provide the translatome of D2R striatal neurons and identified hundreds of region specific molecular markers as well as testing their resource to shed ...
Emma Puighermanal, Laia Castell, Anna Esteve-Codina, Su Melser, Konstantin Kaganovsky, Charleine Zussy, Jihane Boubaker-Vitre, Marta Gut, Stephanie Rialle, Christoph Kellendonk, Elisenda Sanz, Albert Quintana, Giovanni Marsicano, Miquel Martin, Marcelo Rubinstein, Jean-Antoine Girault, Jun B. Ding, Emmanuel Valjent   +17 more
doaj   +1 more source

Polysome profiling in liver identifies dynamic regulation of endoplasmic reticulum translatome by obesity and fasting.

PLoS Genetics, 2012
Obesity-associated metabolic complications are generally considered to emerge from abnormalities in carbohydrate and lipid metabolism, whereas the status of protein metabolism is not well studied.
Suneng Fu, Jason Fan, Joshua Blanco, Alfredo Gimenez-Cassina, Nika N Danial, Steve M Watkins, Gökhan S Hotamisligil   +6 more
doaj   +1 more source

Translatome of dorsal striatum parvalbumin interneurons revisited: insights across diverse experimental paradigms

Frontiers in Cellular Neuroscience
Parvalbumin (PV) interneurons in the dorsal striatum (DS) are fast-spiking GABAergic cells critical for feedforward inhibition and synaptic integration within basal ganglia circuits.
Claire Naon, Laia Castell, Steeve Thirard, Maria Moreno, Stéphanie Rialle, Eva Goetz, Eloi Casals, Eloi Casals, Angelina Rogliardo, Marta Gut, Marta Gut, Anna Esteve-Codina, Anna Esteve-Codina, Albert Quintana, Albert Quintana, Federica Bertaso, Emmanuel Valjent, Laura Cutando, Laura Cutando   +18 more
doaj   +1 more source

Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Adaptive laboratory evolution of a genome-reduced Escherichia coli

Nature Communications, 2019
Genome-reduced bacteria often show impaired growth under laboratory conditions. Here the authors use adaptive laboratory evolution to optimise growth performance and show transcriptome and translatome-wide remodeling of the organism.
Donghui Choe, Jun Hyoung Lee, Minseob Yoo, Soonkyu Hwang, Bong Hyun Sung, Suhyung Cho, Bernhard Palsson, Sun Chang Kim, Byung-Kwan Cho   +8 more
doaj   +1 more source