Results 81 to 90 of about 5,654 (195)

Translational switching from growth to defense – a common role for TOR in plant and mammalian immunity? [PDF]

, 2017
Characterization of mRNA populations associatedwith the translational machinery (translatome)is shedding light on the molecular mechanisms ofplant environmental responses. The work presentedby Meteignier et  al.
Blanco, Flavio Antonio, Zanetti, María Eugenia   +1 more
core   +2 more sources

METTL1‐Mediated M7G tRNA Modification Promotes Residual Liver Regeneration After Hepatectomy via Translational Control

Advanced Science, Volume 13, Issue 12, 27 February 2026.
METTL1 and its mediated m7G tRNA modification are significantly up‐regulated after partial hepatectomy (PHx). Overexpression of METTL1 improves the efficiency of liver regeneration after PHx, increases the proliferation of hepatocytes, and accelerates the recovery of liver function.
Manling Huang, Shuirong Lin, Yutong Zhao, Jiale Chen, Linyuan Huang, Yuyao Liu, Zixin Huang, Dongxin An, Yifan Zhang, Zimin Song, Xi Yu, Yunpeng Hua, Jing Wang, Weiwei Wang, Yu Guo, Ming Kuang, Fang Wang, Shuibin Lin, Shunli Shen   +18 more
wiley   +1 more source

Regulation of the hippocampal translatome by Apoer2-ICD release

Molecular Neurodegeneration, 2023
Abstract Background ApoE4, the most significant genetic risk factor for late-onset Alzheimer’s disease (AD), sequesters a pro-synaptogenic Reelin receptor, Apoer2, in the endosomal compartment and prevents its normal recycling.
Catherine R. Wasser, Gordon C. Werthmann, Eric M. Hall, Kristina Kuhbandner, Connie H. Wong, Murat S. Durakoglugil, Joachim Herz   +6 more
openaire   +3 more sources

Moving toward a precise nutrition: preferential loading of seeds with essential nutrients over non-essential toxic elements [PDF]

, 2014
Plants and seeds are the main source of essential nutrients for humans and livestock. Many advances have recently been made in understanding the molecular mechanisms by which plants take up and accumulate micronutrients such as iron, zinc, copper and ...
David G. Mendoza-Cozatl, Mather A. Khan, Norma Castro-Guerrero   +2 more
core   +2 more sources

Targeting DAP5 Disrupts Alternate Mode of Translational Initiation in Tregs and Potentiates Antitumor Immunity

Advanced Science, Volume 13, Issue 10, 18 February 2026.
Regulatory T cells (Tregs) suppress antitumor immunity. This study identifies that the translation scaffold DAP5/eIF4G2 is upregulated in tumor‐infiltrating Tregs (ti‐Tregs). DAP5 mediates an alternate translation mode to sustain CD25 and MCL‐1 expression, which is critical for ti‐Treg stability and survival in the tumor microenvironment.
Xiaojiang Lai, Guihong Pan, Xixi Feng, Jun Zhang, Yunxia Li, Shanmeizi Zhao, Zhenming Lin, Yun Feng, Wei Bao, Hongyan Yang, Chengmei Xie, Chen Huang, Jun Wang   +12 more
wiley   +1 more source

PHR‐Mediated Pi Starvation Response Mobile Messenger RNAs Represent Noncoding Transcripts in Recipient Tissues

Advanced Science, Volume 13, Issue 4, 19 January 2026.
Mobile messenger RNAs (mRNAs) can travel long distances, serving as systemic signals that participate in plant growth and stress acclimation. This work determines that PHR proteins mediate the Pi starvation response (PSR)‐specific long‐distance transport of mRNAs and that these PSR‐specific mobile mRNAs represent noncoding transcripts in recipient ...
Weiguo Dong, Shuman Wang, Chao Liu, Lulu Qiao, Kai Liu, Qiongli Jin, Xiaorong Mo, Xingxing Shen, Keke Yi, Zhiye Wang   +9 more
wiley   +1 more source

Identification and characterization of the BZR transcription factor family and its expression in response to abiotic stresses in Zea mays L. [PDF]

, 2017
Brassinosteroids (BRs) are plant specific steroidal hormones that play diverse roles in regulating a broad spectrum of plant growth and developmental processes, as well as, in responding to various biotic and abiotic stresses. Extensive research over the
Manoli, Alessandro, Quaggiotti, Silvia, Trevisan, Sara, Varotto, Serena   +3 more
core   +1 more source

Differential Diel Translation of Transcripts With Roles in the Transfer and Utilization of Iron-Sulfur Clusters in Arabidopsis

Frontiers in Plant Science, 2018
Iron-sulfur (Fe-S) clusters are evolutionarily ancient ubiquitous protein cofactors which have mostly catalytic functions but can also have structural roles.
Hongliang Zhang, Ute Krämer
doaj   +1 more source

Lipid Droplet‐Driven Ribosome Collisions Trigger ZAKα‐p38 Signaling to Accelerate Testicular Aging

Aging Cell, Volume 25, Issue 1, January 2026.
Aging‐ and obesity‐driven lipid droplet accumulation in Sertoli cells induces ROS‐mediated ribosome collisions, activating the ZAKα‐p38 pathway to accelerate testicular aging. Pharmacological ZAKα inhibition with Nilotinib rescues age‐related testicular dysfunction, identifying ribotoxic stress as a therapeutic target.
Yanghua Xu, Xiaoyan Shi, Yinghao Yin, Xiaoli Tan, Ningjing Ou, Xiaopeng Tang, Biao Liu, Hongshan Xie, Yuzhuo Chen, Zhitao Han, Jiarong Xu, Zitaiyu Li, Xiaoping Zheng, Hongji Hu, Wenjing Wang, Wanyi Xia, Hao Chen, Yuxin Tang, Liangyu Zhao   +18 more
wiley   +1 more source

Getting Down to Specifics: Profiling Gene Expression and Protein-DNA Interactions in a Cell Type-Specific Manner.

, 2015
The majority of multicellular organisms are comprised of an extraordinary range of cell types, with different properties and gene expression profiles. Understanding what makes each cell type unique, and how their individual characteristics are attributed,
Amatori, Amin, Arlotta, Atreya, Auer, Bacaj, Backes, Barres, Barres, Bartkuhn, Beliakova-Bethell, Berger, Bertheau, Bianchi-Frias, Biase, Birnbaum, Bogdanović, Bonn, Bonn, Bossing, Bowman, Brand, Branda, Buchstaller, Caddick, Cahoy, Challen, Chen, Child, Chintapalli, Chintapalli, Choksi, Chung, Cleary, Cléard, Cléard, Colosimo, Coulbault, Curran, Day, Deal, Deal, del Valle Rodríguez, Deveaux, Dickinson, Distel, Dougherty, Doyle, Dölken, Echelard, Egger, Ekstrand, Emmert-Buck, Espina, Feng, Fernandez, Filion, Fong, Foo, Frøkjaer-Jensen, Fulwyler, Gallardo, Gates, Gay, Gay, Germann, Gerstein, Ghavi-Helm, Gisselbrecht, Giuffrè, Gold, Golic, Gonzalez, Gossen, Graveley, Greene, Griswold, Grün, Gu, Guelen, Guo, Hansen, Harrison, Harzer, Haseloff, He, Heffner, Heiman, Heiman, Hempel, Henry, Herzenberg, Hirokawa, Honig, Horton, Hsu, Hubbard, Hulett, Hupe, Imayoshi, Iyer, Jinek, Julius, Kapeli, Kerk, Kim, Kimura, Kind, Kisseberth, Kistler, Konopka, Kratz, Kunitomo, Kvon, Lai, Lai, Lanier, Laplaze, Lee, Lee, Lee, Legres, Lein, Lewandoski, Lin, Liu, Lobo, Luan, Luo, Luukkonen, Ma, Ma, Madisen, Makker, Manseau, Maret, Marsh, Matsumoto, McGuire, McKay, Meacham, Mello, Mello, Miller, Miltenyi, Mollereau, Mollet, Molyneaux, Murphy, Murray, Mustroph, Nelson, Nieweg, Niwa, Nègre, Ogawa, Okaty, Okaty, Ornitz, Osterwalder, Otsuki, Park, Penalva, Pietersen, Pollen, Potter, Pruszak, Ramezani, Rao, Rhee, Riabinina, Roy, Rädle, Safarík, Sander, Sanz, Sanz, Schauer, Scheer, Scheidl, Schmidt, Schmitz, Schorpp, Schuster, Schütze, Seidl, Seifertova, Shalek, Shi, Snippert, Sonnenblick, Soriano, Southall, Southall, Southall, Southall, Spencer, Srinivasan, St Johnston, Steiner, Stinchcomb, Sugino, Sun, Takahashi, Takayama, Tallafuss, Tang, Thomas, Todman, Tomancak, Toyoda, Tryon, Valvekens, Van Blokland, van Steensel, van Steensel, Vergunst, Vogel, Vogel, Von Stetina, Voutev, Vrana, Wang, Watson, Wei, Welzel, Weng, Wolfram, Woolcock, Wu, Xiao, Yan, Yang, Yao, Yi, Zanetti, Zhang, Zhang, Zhong, Zhu   +239 more
core   +1 more source