Results 101 to 110 of about 4,258 (187)
RiboTag translatomic profiling of Drosophila oenocytes under aging and induced oxidative stress
BMC Genomics, 2019 Background Aging is accompanied with loss of tissue homeostasis and accumulation of cellular damages. As one of the important metabolic centers, liver shows age-related dysregulation of lipid metabolism, impaired detoxification pathway, increased ...
Kerui Huang +5 more
doaj +1 more source
Ribosome-tethered in situ sequencing for single-cell translatome analysis
Translational regulation plays a critical role in shaping cellular states and functions, yet approaches for spatially resolved translatome profiling at single-cell resolution remain limited. Here, we develop Ribosome-tethered In Situ Sequencing (Ribo-ISS)
Chen Lin +8 more
core +1 more source
Abstract A28: Oxygen-dependent translatome remodeling is controlled by eIF2α dephosphorylation
, 2017 Introduction: Eukaryotic translation initiation factor 2α (eIF2α) is a core component of the cellular translation machinery. Alterations in eIF2α phosphorylation constitute a key adaptation during a variety of physiological stresses, including oxygen ...
Ayalivis De La Rosa +9 more
core +1 more source
The effect of heterogeneous Transcription Start Sites (TSS) on the translatome: implications for the mammalian cellular phenotype [PDF]
, 2015 The genetic program, as manifested as the cellular phenotype, is in large part dictated by the cell's protein composition. Since characterisation of the proteome remains technically laborious it is attractive to define the genetic expression profile ...
Patrick B. F. O’Connor +17 more
core +1 more source
Nature Communications, 2016 Bacteria of the genus Streptomyces produce a great variety of natural products, the biosynthesis of which is subject to complex regulatory networks. Here the authors present a high-resolution, genome-wide analysis of the transcriptome and translatome of ...
Yujin Jeong +10 more
doaj +1 more source
Scientific Reports, 2017 The epidemic of obesity and diabetes has markedly spurred the research interest in adipocyte biology. Brown adipocytes are specialized for energy expenditure and of therapeutic interest for treatment of metabolic diseases, but how brown adipocytes are ...
David W. Reid +4 more
doaj +1 more source
, 2019 Regulation of translation is essential during stress. However, the precise sets of proteins regulated by the key translational stress responses—the integrated stress response (ISR) and mTORC1—remain elusive.
Tascher, Georg +2 more
core +1 more source
, 2019 Table S3. Usage frequency of HEK293-derived representative TSSs in 180 human samples. All 3248 representative TSSs are from HEK293 translatome. In the table, â1â means the representative TSS (row name) is also used as representative TSS in the sample
Jielin Sun (123338) +7 more
core +1 more source
, 2019 Table S5. Comparison of genes’ abundance between translatome and transcriptome. “Ep”, “Et” and “Sfc” are all defined in the main text. “p-value” and “q-value” are calculated with the R package of DEGseq. Genes are ranked by the q-value.
Jielin Sun (123338) +7 more
core +1 more source
Plenary Abstracts Session & Oral Presentations
HemaSphere, Volume 10, Issue S1, June 2026.
wiley +1 more source