Results 41 to 50 of about 4,258 (187)
Endothelial heterogeneity across distinct vascular beds during homeostasis and inflammation
eLife, 2020 Blood vessels are lined by endothelial cells engaged in distinct organ-specific functions but little is known about their characteristic gene expression profiles.
Ankit Jambusaria +8 more
doaj +1 more source
Selection of Cashmere Fineness Functional Genes by Translatomics [PDF]
Frontiers in Genetics, 2022 Cashmere fineness is an important index to evaluate cashmere quality. Liaoning Cashmere Goat (LCG) has a large cashmere production and long cashmere fiber, but its fineness is not ideal. Therefore, it is important to find genes involved in cashmere fineness that can be used in future endeavors aiming to improve this phenotype.
Yu Zhang +11 more
openaire +3 more sources
Genetic regulation of maize floral development - insights from the transcriptome and translatome
, 2023 Flowers are produced by floral meristems, groups of stem cells that give rise to floral organs. In grasses, including the major cereal crops, flowers (florets) are contained in spikelets, which contain one to many florets, depending on the species ...
NC DOCKS at East Carolina University +1 more
core +1 more source
Inhibition of protein translation under matrix-deprivation stress in breast cancer cells
Frontiers in Medicine, 2023 Matrix-deprivation stress leads to cell-death by anoikis, whereas overcoming anoikis is critical for cancer metastasis. Work from our lab and others has identified a crucial role for the cellular energy sensor AMPK in anoikis-resistance, highlighting a ...
Shweta Warrier +3 more
doaj +1 more source
The translatome of Glioblastoma multiforme
, 2022 Abstract Glioblastoma Multiforme (GBM) is the most common and aggressive brain tumor, containing intrinsic resistance to current therapies leading to poor clinical outcomes. Therefore, understanding the underlying mechanisms of GBM is an urgent medical need. Although radiotherapy contributes significantly to patient survival, GBMs recur
F. M.G. Cornelissen +9 more
openaire +1 more source
mSystems, 2021 Cyanobacteria are promising industrial platforms owing to their ability to produce diverse natural secondary metabolites and nonnative value-added biochemicals from CO2 and light.
Sang-Hyeok Cho +8 more
doaj +1 more source
Astonishing advances in mouse genetic tools for biomedical research
Swiss Medical Weekly, 2015 The humble house mouse has long been a workhorse model system in biomedical research. The technology for introducing site-specific genome modifications led to Nobel Prizes for its pioneers and opened a new era of mouse genetics.
Walker Scot Jackson, Lech Kaczmarczyk
doaj +1 more source
The 40 S -LARP1 complex reprograms the cellular translatome upon mTOR inhibition to preserve the protein synthetic capacity [PDF]
, 2021 Ribosomes execute the transcriptional program in every cell. Critical to sustain nearly all cellular activities, ribosome biogenesis requires the translation of ~200 factors of which 80 are ribosomal proteins (RPs).
Martinez Herráez, Carolina +11 more
core +1 more source
Schematic overview of a translatome experiment.
, 2017 Schematic overview of a translatome experiment.
Christian Lange (70151) +7 more
core +1 more source
Translatome profiling: methods for genome-scale analysis of mRNA translation [PDF]
, 2015 During the past decade, there has been a rapidly increased appreciation of the role of translation as a key regulatory node in gene expression. Thereby, the development of methods to infer the translatome, which refers to the entirety of mRNAs associated
Gerber, AP, King, HA
core +1 more source