Results 41 to 50 of about 5,654 (195)

Molecular Mechanisms of Persistence in Protozoan Parasites

open access: yesMicroorganisms, 2023
Protozoan parasites are known for their remarkable capacity to persist within the bodies of vertebrate hosts, which frequently results in prolonged infections and the recurrence of diseases.
Asfiha Tarannum   +3 more
doaj   +1 more source

Tissue- and stage-specific landscape of the mouse translatome [PDF]

open access: yesNucleic Acids Research, 2021
Abstract The current understanding of how overall principles of translational control govern the embryo-to-adult transition in mammals is still far from comprehensive. Herein we profiled the translatomes and transcriptomes of six tissues from the mice at embryonic and adult stages and presented the first report of tissue- and stage ...
Hongwei Wang   +10 more
openaire   +3 more sources

Endothelial heterogeneity across distinct vascular beds during homeostasis and inflammation

open access: yeseLife, 2020
Blood vessels are lined by endothelial cells engaged in distinct organ-specific functions but little is known about their characteristic gene expression profiles.
Ankit Jambusaria   +8 more
doaj   +1 more source

Stable maternal proteins underlie distinct transcriptome, translatome, and proteome reprogramming during mouse oocyte-to-embryo transition

open access: yesGenome Biology, 2023
Background The oocyte-to-embryo transition (OET) converts terminally differentiated gametes into a totipotent embryo and is critically controlled by maternal mRNAs and proteins, while the genome is silent until zygotic genome activation.
Hongmei Zhang   +17 more
doaj   +1 more source

Inhibition of protein translation under matrix-deprivation stress in breast cancer cells

open access: yesFrontiers in Medicine, 2023
Matrix-deprivation stress leads to cell-death by anoikis, whereas overcoming anoikis is critical for cancer metastasis. Work from our lab and others has identified a crucial role for the cellular energy sensor AMPK in anoikis-resistance, highlighting a ...
Shweta Warrier   +3 more
doaj   +1 more source

Different Regulatory Modes of Synechocystis sp. PCC 6803 in Response to Photosynthesis Inhibitory Conditions

open access: yesmSystems, 2021
Cyanobacteria are promising industrial platforms owing to their ability to produce diverse natural secondary metabolites and nonnative value-added biochemicals from CO2 and light.
Sang-Hyeok Cho   +8 more
doaj   +1 more source

The malignant phenotype in breast cancer is driven by eIF4A1-mediated changes in the translational landscape [PDF]

open access: yes, 2015
Human mRNA DeXD/H-box helicases are ubiquitous molecular motors that are required for the majority of cellular processes that involve RNA metabolism. One of the most abundant is eIF4A, which is required during the initiation phase of protein synthesis to
A De Benedetti   +51 more
core   +1 more source

Dissecting apoptosis the omics way [PDF]

open access: yes, 2013
A combined analysis of transcription, translation and protein degradation reveals the global effects of an anticancer drug on tumour ...
Agard   +8 more
core   +2 more sources

A comparison between whole transcript and 3' RNA sequencing methods using Kapa and Lexogen library preparation methods. [PDF]

open access: yes, 2019
Background3' RNA sequencing provides an alternative to whole transcript analysis. However, we do not know a priori the relative advantage of each method.
Fuqua, Brie K   +6 more
core   +1 more source

A comprehensive analysis of the importance of translation initiation factors for Haloferax volcanii applying deletion and conditional depletion mutants [PDF]

open access: yes, 2013
Translation is an important step in gene expression. The initiation of translation is phylogenetically diverse, since currently five different initiation mechanisms are known.
Gäbel, Katrin   +4 more
core   +3 more sources

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