Results 41 to 50 of about 168,078 (169)
A custom library construction method for super-resolution ribosome profiling in Arabidopsis
Plant Methods, 2022 Background Ribosome profiling, also known as Ribo-seq, is a powerful technique to study genome-wide mRNA translation. It reveals the precise positions and quantification of ribosomes on mRNAs through deep sequencing of ribosome footprints.
Hsin-Yen Larry Wu, Polly Yingshan Hsu
doaj +1 more source
Frontiers in Oncology, 2021 Cutaneous melanoma (CMM) is a skin tumor with a high degree of malignancy. BRAF resistance imposes great difficulty to the treatment of CMM, and partially contributes to the poor prognosis of CMM.
Tianhong Wei, Lan Li, Zhiyou He
doaj +1 more source
Integrated workflow for discovery of microprotein-coding small open reading frames
STAR Protocols, 2023 Summary: Small open reading frame (smORF)-encoded microproteins, proteins containing less than 100–150 amino acids, are an emerging class of functional biomolecules.
Kevin Cao +3 more
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Reliable detection of translational regulation with Ribo-seq [PDF]
, 2017 Ribosome profiling (Ribo-Seq) reveals genome-wide translation rates via the quantification of ribosome protected fragments (RPFs) of mRNAs. Several methods have recently been developed to detect differentially translated genes (DTGs) using Ribo-seq: Xtail, Ribodiff and Riborex. At their core, all of these approaches either utilize existing differential
Chothani, Sonia P +6 more
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Visualizing the periodic Ribo-seq reads with RiboPlotR [PDF]
, 2019 ABSTRACT Background Ribo-seq has revolutionized the study of mRNA translation in a genome-wide scale. High-quality Ribo-seq data display strong 3-nucleotide (nt) periodicity, which corresponds to translating ribosomes decipher three nucleotides each time.
Wu, Hsin-Yen Larry, Hsu, Polly Yingshan
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Differential analysis of Ribo-seq and RNA-seq read counts by genomic feature.
, 2023 Differential analysis of Ribo-seq and RNA-seq read counts by genomic feature.
Andrew A. Smith (17041553) +9 more
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Data-driven design of LNA-blockers for efficient contaminant removal in Ribo-Seq libraries. [PDF]
Sci RepAbstract Ribo-Seq libraries often contain highly abundant non-coding RNA contaminants, which are challenging to remove due to their high sequence variability and diverse fragmentation patterns. We present an organism-independent computational pipeline that identifies experiment-specific target sequences and enables their efficient ...
Ricciardi DA, Peter FE, Böhmer M.
europepmc +4 more sources
Fig1B AspRS ribo-seq reads in WT and dfrq
, 2023 Fig1B AspRS ribo-seq reads in WT and dfrq
Kathrina Castillo (13712005)
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GWIPS-viz: development of a ribo-seq genome browser
Nucleic Acids Research, 2013 We describe the development of GWIPS-viz (http://gwips.ucc.ie), an online genome browser for viewing ribosome profiling data. Ribosome profiling (ribo-seq) is a recently developed technique that provides genome-wide information on protein synthesis (GWIPS) in vivo. It is based on the deep sequencing of ribosome-protected messenger RNA (mRNA) fragments,
Audrey M. Michel +9 more
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Fig1C GlnRS ribo-seq reads in WT and dfrq.csv
, 2023 Fig1C GlnRS ribo-seq reads in WT and ...
Kathrina Castillo (13712005)
core +1 more source