Results 51 to 60 of about 168,078 (169)

Repurposing Ribo-Seq to provide insights into structured RNAs [PDF]

open access: yes, 2020
Abstract Ribosome profiling (Ribo-Seq) is a powerful method to study translation in bacteria. However, this method can enrich RNAs that are not bound by ribosomes, but rather, are protected from degradation in another way.
Brayon J. Fremin, Ami S. Bhatt
openaire   +1 more source

RiboNT: A Noise-Tolerant Predictor of Open Reading Frames from Ribosome-Protected Footprints

open access: yesLife, 2021
Ribo-seq, also known as ribosome profiling, refers to the sequencing of ribosome-protected mRNA fragments (RPFs). This technique has greatly advanced our understanding of translation and facilitated the identification of novel open reading frames (ORFs ...
Bo Song, Mengyun Jiang, Lei Gao
doaj   +1 more source

Fig1A WT and dfrq ribo-seq data for heatmaps

open access: yes, 2023
Fig1A WT and dfrq ribo-seq data for heatmaps 
Kathrina Castillo (13712005)   +1 more
core   +1 more source

Physical modeling of ribosomes along messenger RNA: Estimating kinetic parameters from ribosome profiling experiments using a ballistic model.

open access: yesPLoS Computational Biology, 2023
Gene expression is the synthesis of proteins from the information encoded on DNA. One of the two main steps of gene expression is the translation of messenger RNA (mRNA) into polypeptide sequences of amino acids.
Carole Chevalier   +11 more
doaj   +1 more source

Compatible levels of editing between Ribo-seq and RNA-seq data.

open access: yes, 2023
Levels of A-to-I editing in left ventricle DCM patients from RNA-seq (n = 37) and Ribo-seq (n = 30) datasets. Cutoff of ≥ 10 reads for each site. (JPG)
Tomer D. Mann (15203465)   +3 more
core   +1 more source

Discovering microproteins: making the most of ribosome profiling data

open access: yesRNA Biology, 2023
Building a reference set of protein-coding open reading frames (ORFs) has revolutionized biological process discovery and understanding. Traditionally, gene models have been confirmed using cDNA sequencing and encoded translated regions inferred using ...
Sonia Chothani   +3 more
doaj   +1 more source

A community-driven roadmap to advance research on translated open reading frames detected by Ribo-seq

open access: yes, 2021
Ribosome profiling (Ribo-seq) has catalyzed a paradigm shift in our understanding of the translational ‘vocabulary’ of the human genome, discovering thousands of translated open reading frames (ORFs) within long non-coding RNAs and presumed untranslated ...
Schulz, Jana Felicitas   +27 more
core   +1 more source

Optimization of carbon and energy utilization through differential translational efficiency

open access: yesNature Communications, 2018
Microorganisms must regulate allocation of resources in nutrient-limited conditions. Here, the authors combine Ribo-seq, RNA-seq and TSS-seq to study resource allocation in the acetogen C.
Mahmoud M. Al-Bassam   +7 more
doaj   +1 more source

Summary of the mRNA-Seq and Ribo-Seq results.

open access: yes, 2018
Summary of the mRNA-Seq and Ribo-Seq results.
Liping Wei (10166)   +5 more
core   +1 more source

De novo functional transcriptomics with RNA-seq and Ribo-seq

open access: yes, 2023
Our genome sequencing and assembly capabilities have hugely increased. However, annotating our genome is still challenging. Genes can produce multiple isoforms, which may have different expression levels and roles. Transcript functions can be elucidated by profiling ribosome positions with the protocol Ribo-seq.
Albanese, Roberto   +5 more
openaire   +1 more source

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