Results 71 to 80 of about 168,078 (169)
Fig2A-B AspRS and GlnRS ribo-seq reads in WT and dfrq.csv
, 2022 Fig2A-B AspRS and GlnRS ribo-seq reads in WT and ...
Kathrina Castillo (13712005)
core +1 more source
Nature CommunicationsThere has been a dramatic increase in the identification of non-canonical translation and a significant expansion of the protein-coding genome. Among the strategies used to identify unannotated small Open Reading Frames (smORFs) that encode microproteins,
Eduardo Vieira de Souza +7 more
doaj +1 more source
Translatome and transcriptome analysis of TMA20 (MCT-1) and TMA64 (eIF2D) knockout yeast strains
Data in Brief, 2019 TMA20 (MCT-1), TMA22 (DENR) and TMA64 (eIF2D) are eukaryotic translation factors involved in ribosome recycling and re-initiation. They operate with P-site bound tRNA in post-termination or (re-)initiation translation complexes, thus participating in the
Desislava S. Makeeva +11 more
doaj +1 more source
Mutant KRAS‐m6A Epitranscriptome Axis Promotes Colorectal Cancer and is a Therapeutic Target
Advanced Science, EarlyView.Mutant KRAS‐m6A axis promotes colorectal cancer (CRC) progression. Mutant KRAS stabilizes METTL3, leading to increased m6A‐modified BCL9L mRNA and translation of BCL9L protein. BCL9L in turn mediates TGF‐β secretion to induce differentiation of Treg and an immunosuppressive microenvironment.
Danyu Chen +12 more
wiley +1 more source
Establishment and characterization of mouse lymph node fibrosis models
Animal Models and Experimental Medicine, EarlyView.The design of the entire paper. Schematic illustration of four strategies for establishing mouse lymph node (LN) fibrosis models. The study further compares their fibrotic remodeling patterns and immune alterations. Abstract Background Lymph node (LN) fibrosis occurs in a variety of pathological conditions, including HIV infection, obesity, cancer, and
Yaru Niu +8 more
wiley +1 more source
Experimental and Molecular Medicine, 2023 Translational regulation in tissue environments during in vivo viral pathogenesis has rarely been studied due to the lack of translatomes from virus-infected tissues, although a series of translatome studies using in vitro cultured cells with viral ...
Junsoo Kim +27 more
doaj +1 more source
Sheep Horn Development Revealed by Multi‐Tissue and Cross‐Species Transcriptomic Analysis
Animal Research and One Health, EarlyView.Multi‐tissue and cross‐species transcriptomics with allele‐specific expression show sheep horns are a composite organ integrating epidermal and osteogenic programs. Conserved horn gene modules and cis‐regulatory variation fine‐tune expression networks underlying horn development and size (small scurs vs. large spiral horns).
Hao Li +10 more
wiley +1 more source
Translating the green code: Ribo-Seq for photosynthetic eukaryotes in focus
The Journal of BiochemistryAbstract Because they are continually exposed to fluctuating environments, photosynthetic organisms, including land plants and algae, must adapt to a wide range of environmental conditions. For this purpose, translational control plays a pivotal role.
Naohiro Kawamoto, Shintaro Iwasaki
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RiboSeq.Org:resources for the alignment, analysis and exploration of ribo-seq data
, 2016 The ribosome profiling (ribo-seq) technique uses high-throughput sequencing to reveal the global locations and densities of ribosome protected mRNA fragments. On RiboSeq.Org (http://riboseq.org/) we provide freely available resources to help researchers analyse and explore ribo-seq data without having to use command-line tools.
Michel, Audrey +9 more
openaire +1 more source
Extensive translation of small ORFs revealed by polysomal ribo-Seq [PDF]
, 2014 ABSTRACT Thousands of small Open Reading Frames (smORFs) encoding small peptides of fewer than 100 amino acids exist in our genomes. Examples of functional smORFs have been characterised in a few species but the actual number of translated smORFs, and their molecular, functional and evolutionary features are not known. Here we present a
Aspden, Julie L +5 more
openaire +1 more source