Results 81 to 90 of about 168,078 (169)
Frontiers in Nutrition, 2021 An excessive high-fat/energy diet is a major cause of obesity and linked complications, such as non-alcoholic fatty liver disease (NAFLD). Betaine has been shown to effectively improve hepatic lipid metabolism.
Tengda Huang +12 more
doaj +1 more source
BMEMat, EarlyView.The construct of cell‐niche co‐aggregates (GelMA‐SHED sphere‐DDMPs) promotes cranial and periodontal bone regeneration and ensures angiogenic‐osteogenic coupling by downregulating miR‐34c‐5p to enhance the expression of NOTCH1 and its intracellular domain (NICD).
Xiao‐Hui Zhang +23 more
wiley +1 more source
Quality control analysis of Ribo-seq data.
, 2023 (A) PCA of gene expression in Ribo-seq biological replicates, n = 3; see S1 Data. (B) Length distribution of RPFs; see S1 Data. All downstream analysis was restricted to the dominant fragment size of 26–29 nt.
Andrew A. Smith (17041553) +9 more
core +1 more source
Poultry Science, 2021 : Deep sequencing of RNAs has greatly aided the study of the transcriptome, enabling comprehensive gene expression profiling and the identification of novel transcripts. While messenger RNAs (mRNAs) are of the greatest interest in gene expression studies
Hanwen Gu, Yu H. Sun, Xin Zhiguo Li
doaj +1 more source
Derivation of Mouse Dome‐Shaped Trophoblast Stem Cells With Low Heterogeneity From Blastocysts
Cell Proliferation, EarlyView.Here, Liu et al. report the generation of mouse dome‐shaped trophoblast stem cells (dTSCs) with low heterogeneity and autonomous differentiation potential. dTSCs robustly generate all trophoblast lineages in vitro and contribute to the placenta in vivo, providing a refined model for studying trophoblast development and related disorders.
Minli Liu +8 more
wiley +1 more source
, 2017 Riboswitches are structural genetic regulatory elements that directly couple the sensing of small molecules to gene expression. They have considerable potential for applications throughout synthetic biology and bio-manufacturing as they are able to sense
Tom Newport (643261)
core +1 more source
Physiological media and oxygen levels modulate cancer hallmarks in cultured breast cancer cells
The FEBS Journal, EarlyView.MCF7 breast cancer cells were cultured in standard conditions (18% O2 and DMEM) and physiological conditions (5% O2 and Plasmax, a medium modeled after the human plasma metabolome). A combined transcriptomic and proteomic approach was used to identify gene expression signatures at the mRNA and protein levels upstream of functional enrichment analyses ...
Jacob E. Wiebe +5 more
wiley +1 more source
gmtong/Ribo-seq-Tool-Comparison-Scripts: Ribo-seq-Tool-Comparison-Scripts
<p>Scripts for recreating analysis for the paper "Comparison of software packages for detecting unannotated small open reading frame translation by Ribo-seq"</p ...
gmtong
core +1 more source
Methods, Challenges and Potentials of Single Cell RNA-seq [PDF]
, 2012 RNA-sequencing (RNA-seq) has become the tool of choice for transcriptomics. Several recent studies demonstrate its successful adaption to single cell analysis. This allows new biological insights into cell differentiation, cell-to-cell variation and gene
Daniel Hebenstreit, Hebenstreit, Daniel
core +1 more source
Abridged Ribosome Profiling for Accurate Bacterial Translation Measurements
Methods and ProtocolsRibosome profiling, or Ribo-Seq, is a powerful tool for studying translation. It maps the positions of translating ribosomes on mRNAs, providing insights into actively expressed genes. Unlike mass spectrometry, Ribo-Seq is not affected by the same biases
Marc Follmer +2 more
doaj +1 more source