Non-invasive detection of nanoscale structural changes in cornea associated with cross-linking treatment [PDF]
, 2020 Corneal cross-linking (CXL) using UVA irradiation with a riboflavin photosensitizer has grown from an interesting concept to a practical clinical treatment for corneal ectatic diseases globally, such as keratoconus. To characterize the corneal structural changes, existing methods such as X-ray microscopy, transmission electron microscopy (TEM ...
arxiv +1 more source
Clinical Ophthalmology, 2021 Roy S Rubinfeld,1 Glenwood G Gum,2 Jonathan H Talamo,1,3 Edward C Parsons1 1CXL Ophthalmics, LLC, Encinitas, CA, USA; 2Absorption Systems California, LLC, San Diego, CA, USA; 3Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School,
Rubinfeld RS +3 more
doaj
Biotechnological Strategies of Riboflavin Biosynthesis in Microbes
Engineering, 2022 Riboflavin is an essential micronutrient for humans and must be obtained exogenously from foods or supplements. Numerous studies have suggested a major role of riboflavin in the prevention and treatment of various diseases.
Jia-Rong Zhang +7 more
doaj
Lactococcus lactis is capable of improving the riboflavin status in deficient rats [PDF]
, 2005 Lactococcus lactis is a commonly used starter strain that can be converted from a vitamin B2 consumer into a vitamin B2 'factory' by over-expressing its riboflavin biosynthesis genes.
Burgess, Catherine M. +4 more
core +1 more source
Bio prospecting of Riboflavin producing bacteria from different riboflavin enriched food sources
Bioscience Journal, 2022 Riboflavin is an essential, water-soluble vitamin (B2) and a component of basic cellular metabolism. The aim of the present study is to isolate and characterize riboflavin producing bacteria from different food sources.
M Hemalatha, C Subathra Devi
doaj +1 more source
Supplementation of iron alone and combined with vitamins improves haematological status, erythrocyte membrane fluidity and oxidative stress in anaemic pregnant women [PDF]
, 2010 Pregnancy is a condition exhibiting increased susceptibility to oxidative stress, and Fe plays a central role in generating harmful oxygen species. The objective of the present study is to investigate the changes in haematological status, oxidative ...
Aiguo, M. +7 more
core +2 more sources
Riboflavin-Responsive and -Non-responsive Mutations in FAD Synthase Cause Multiple Acyl-CoA Dehydrogenase and Combined Respiratory-Chain Deficiency [PDF]
, 2017 open48siMultiple acyl-CoA dehydrogenase deficiencies (MADDs) are a heterogeneous group of metabolic disorders with combined respiratory-chain deficiency and a neuromuscular phenotype.
core +1 more source
Riboflavin-Targeted Drug Delivery
Cancers, 2020 Active targeting can improve the retention of drugs and drug delivery systems in tumors, thereby enhancing their therapeutic efficacy. In this context, vitamin receptors that are overexpressed in many cancers are promising targets.
Milita Darguzyte +3 more
semanticscholar +1 more source
Interdependency of regulatory effects of iron and riboflavin in the foodborne pathogen Shigella flexneri determined by integral transcriptomics [PDF]
PeerJ, 2020 Shigella flexneri is the causative agent of dysentery. For pathogens, iron is a critical micronutrient as its bioavailability is usually low in bacterial niches.
Luis Fernando Lozano Aguirre +3 more
doaj +2 more sources
Kinetics and thermodynamics of the binding of riboflavin, riboflavin 5′-phosphate and riboflavin 3′,5′-bisphosphate by apoflavodoxins [PDF]
Biochemical Journal, 1996 The reactions of excess apoflavodoxin from Desulfovibrio vulgaris, Anabaena variabilis and Azotobacter vinelandii with riboflavin 5´-phosphate (FMN), riboflavin 3´,5´-bisphosphate and riboflavin are pseudo-first-order. The rates increase with decreasing pH in the range pH 5–8, and, in general, they increase with increasing ionic strength to approach a ...
Pueyo Dabad, José Javier +2 more
openaire +5 more sources