Results 61 to 70 of about 140,350 (392)

Metabolic engineering of thermophilic Bacillus methanolicus for riboflavin overproduction from methanol

Microbial Biotechnology, 2023
The growing need of next generation feedstocks for biotechnology spurs an intensification of research on the utilization of methanol as carbon and energy source for biotechnological processes.
Vivien Jessica Klein, Luciana Fernandes Brito, Fernando Perez‐Garcia, Trygve Brautaset, Marta Irla   +4 more
doaj   +1 more source

Reengineering Endogenous Targeting Lipid Nanoparticles (ENDO) for Systemic Delivery of mRNA to Pancreas

Advanced Materials, EarlyView.
ENDO lipid nanoparticles containing cholecalciferol as a fifth component demonstrate mRNA delivery to the pancreas with 99% selectivity, including beta cells. This platform shows minimal toxicity and sustained protein expression for up to 3 days in a dose‐dependent manner, offering a novel approach to pancreas‐specific mRNA delivery and gene therapy ...
Ivan Isaac, Luv Patel, Nguyen Tran, Amarnath Singam, DongSoo Yun, Prasun Guha, Seungman Park, Chandrabali Bhattacharya   +7 more
wiley   +1 more source

Engineering thermophilic Geobacillus thermoglucosidasius for riboflavin production

Microbial Biotechnology, 2020
The potential advantages for fermentation production of chemicals at high temperatures are attractive, such as promoting the rate of biochemical reactions, reducing the risk of contamination and the energy consumption for fermenter cooling. In this work,
Zhiheng Yang, Qingqing Sun, Gaoyi Tan, Quanwei Zhang, Zhengduo Wang, Chuan Li, F. Qi, Weishan Wang, Lixin Zhang, Zilong Li   +9 more
semanticscholar   +1 more source

Miniaturized Devices for On‐the‐Spot Generation of Small‐Diameter Vascular Grafts

Advanced Materials Technologies, EarlyView.
An intracorporeal extrusion device is developed for on‐the‐spot generation of vascular grafts with tunable diameters spanning from 1 to 6 mm. The device uses biomimetic polymers and light, to promptly obtaining biocompatible and high‐burst pressure‐resistant grafts.
Deyanira Hernandez‐Sanchez, Maxime‐Emmanuel Comtois‐Bona, Antony El‐Khoury, Sergio David Garcia Schejtman, Aidan Macadam, Juan‐David Figueroa‐Alegria, Jesus M. Calderon‐Torres, Irene Guzmán‐Soto, Marc Ruel, Erik J. Suuronen, Marcelo Muñoz, Emilio I. Alarcon   +11 more
wiley   +1 more source

Mass spectrometry in ocular drug research

Mass Spectrometry Reviews, EarlyView., 2023
Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo, Kati‐Sisko Vellonen, Arto Urtti, Tetsuya Terasaki, Anam Hammid, Paavo Honkakoski, Seppo Auriola   +6 more
wiley   +1 more source

Marine yeast isolation and industrial application [PDF]

, 2014
Over the last century, terrestrial yeasts have been widely used in various industries, such as baking, brewing, wine, bioethanol and pharmaceutical protein production. However, only little attention has been given to marine yeasts. Recent research showed
Abdelrahman Saleh Zaky, Agnihotri, Amornrattanapan, Apte, Baheri, Bankar, Beuchat, Bharathi, Bondesson, Boretsky, Bowen, Buhagiar, Chandel, Chen, Chenyu Du, Chi, Chi, Chi, Chi, Chi, Chi, Cong, Connell, Cooper, Dinesh, Du, Duarte, Faiura, Fell, Gao, Gao, Gen, Gill, Gregory A. Tucker, Gupta, Hernandez-Saavedra, Hernandez-Saavedra, Higuera-Ciapara, Jain, Jannasch, Jarvis, Kathiresan, Katre, Khambhaty, King, Kodama, Kohlmeyer, Kutty, Leathers, Li, Li, Li, Li, Li, Libkind, Limtong, Lin, Liu, Liu, Loureiro, Masuda, Murugappan, Nagahama, Neuman, Obara, Oswal, Pandey, Peng, Peng, Pensupa, Ramirez-Orozco, Renshaw, Saravanakumar, Sarkar, Sarlin, Senthilraja, Stahmann, Subramanian, Thomson, Turkiewicz, Urano, Ushakumari, Wang, Wang, Wang, Watson, Wickerham, Winkelmann, Wu, Yanagisawa, Zakaria Yehia Daw, Zhang, Zhang, Zhang   +93 more
core   +1 more source

Riboflavin Supplementation in Patients with Crohn’s Disease [the RISE-UP study]

Journal of Crohn's & Colitis, 2019
Background and Aims Crohn’s disease [CD] is characterised by chronic intestinal inflammation and dysbiosis in the gut. Riboflavin [vitamin B2] has anti-inflammatory, antioxidant and microbiome-modulatory properties.
J. V. von Martels, A. Bourgonje, M. Klaassen, H. A. Alkhalifah, M. Sadaghian Sadabad, A. Vich Vila, R. Gacesa, Ruben Y. Gabriëls, R. Steinert, B. Jansen, M. Bulthuis, H. V. van Dullemen, M. Visschedijk, E. Festen, R. Weersma, P. de Vos, H. van Goor, K. Faber, H. Harmsen, G. Dijkstra   +19 more
semanticscholar   +1 more source

Riboflavin metabolism: role in mitochondrial function

, 2020
Riboflavin, known as vitamin B2, a water-soluble vitamin, is an essential nutrient in vertebrates, hence adequate dietary intake is imperative. Riboflavin plays a role in a variety of metabolic pathways, serving primarily as an integral component of its ...
S. Balasubramaniam, J. Yaplito-Lee
semanticscholar   +1 more source

Microlasers Made Entirely from Edible Substances

Advanced Optical Materials, EarlyView.
Several types of microlasers made completely out of edible substances are developed. They can be embedded directly into edible products and enable the sensing of various parameters, including sugar concentration, pH, the presence of bacteria, and exposure to too‐high temperatures.
Abdur Rehman Anwar, Maruša Mur, Georgia Michailidou, Dimitrios N. Bikiaris, Matjaž Humar   +4 more
wiley   +1 more source

Riboflavin concentration in corneal stroma after intracameral injection [PDF]

International Journal of Ophthalmology, 2015
AIM:To evaluate the enrichment of riboflavin in the corneal stroma after intracameral injection to research the barrier ability of the corneal endothelium to riboflavin in vivo.METHODS:The right eyes of 30 New Zealand white rabbits were divided into ...
Na Li, Xiu-Jun Peng, Zheng-Jun Fan, Xu Pang, Yu Xia, Teng-Fei Wu   +5 more
doaj   +1 more source