Results 91 to 100 of about 571,237 (168)

Minimally processed, human‐grade diet alters canine epigenetic ageing: Results from a pilot study

Veterinary Record Open, Volume 13, Issue 2, December 2026.
Abstract Background Diet plays a critical role in promoting wellness and longevity in both humans and canines. Epigenetic ageing clocks have emerged as accurate tools for assessing biological ageing and evaluating dietary and lifestyle interventions in humans and mice.
Aimee Chen, Wei Guo, Janina A. Krumbeck, Dan Su, Vincent Michels, Xiaojing Yang   +5 more
wiley   +1 more source

An intronic variation in SLC52A1 causes exon skipping and transient riboflavin-responsive multiple acyl-CoA dehydrogenation deficiency

, 2017
Vitamin B2, riboflavin is essential for cellular function, as it participates in a diversity of redox reactions central to human metabolism, through its role as precursor for the cofactors flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD),
Gregersen, Niels, Mosegaard, Signe, Brage S. Andresen, Signe Mosegaard, Flyvbjerg, Karen Freund, Annexstad, Ellen, Gitte Hoffmann Bruun, Dembic, Maja, Niels Gregersen, Yngve Thomas Bliksrud, Tangeraas, Trine, Olsen, Rikke Katrine Jentoft, Ellen Annexstad, Karen Freund Flyvbjerg, Bliksrud, Yngve Thomas, Trine Tangeraas, Maja Dembic, Bruun, Gitte Hoffmann, Rikke Katrine Jentoft Olsen, Andresen, Brage S   +19 more
core   +1 more source

The appropriate dietary methionine content reduces deamination and gluconeogenesis in Chinese perch (Siniperca chuatsi)

Journal of the World Aquaculture Society, Volume 57, Issue 5, October 2026.
Abstract This study evaluated the effects of different dietary methionine (Met) levels on the feeding, growth, and protein metabolism of Chinese perch, Siniperca chuatsi. Six diets containing graded levels of Met (0.88%, 1.11%, 1.68%, 2.02%, 2.27%, and 2.72%) were fed to fish (initial weight: 13.74 ± 0.12 g) for 8 weeks.
Xinyao Ji, Jiacheng Hu, Baoye Hao, Jinguo Chen, Binhua Niu, Yufei Zhang, Xu‐Fang Liang, Liwei Liu   +7 more
wiley   +1 more source

Mechanism‐Driven Nanoformulations for Cognitive Impairment Induced by Intermittent Hypoxia and Periodontitis

Advanced Materials, Volume 38, Issue 49, 1 September 2026.
Clinically, intermittent hypoxia (IH) is often accompanied by periodontitis, which accelerates cognitive impairment induced by IH. Novel Janus mesoporous gold‐silica nanoformulations (RVG‐Au&mSiO2‐TPP‐VB) enable intranasal delivery, achieve hierarchical targeting to neuronal mitochondria, effectively scavenge reactive oxygen species, inhibit the HIF‐1α/
Kai‐Run Zhang, Tianbao Zhu, An‐Qi Liu, Jia‐Jia Deng, Ya‐Li Han, Sheng‐Cai Qi, Xue Liu, Tian‐Yi Jiang, Ming‐Rui Zhai, Yu‐Ying He, Xiu‐Juan Li, Hong‐Ting Da, Rui Xu, Xiaomin Li, Jun Gao, Yue‐Hua Liu   +15 more
wiley   +1 more source

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, Volume 13, Issue 50, 7 September 2026.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng, Zhicheng Wang, Xin Zhou, Shuya Wang, Xiaojing Shi, Tingli Xiong, Ruishi Li, Yuting Lin, Zhen Chen, Jiawen Wei, Fei Li, Jinwen Ge, Kelong Ai, Chong Liu, Guiming Deng   +14 more
wiley   +1 more source

Response of an Infant With Presumed Multiple Acyl‐CoA Dehydrogenase Deficiency (MADD) to Ketone Supplementation

American Journal of Medical Genetics Part A, Volume 200, Issue 9, Page 2140-2150, September 2026.
ABSTRACT Multiple Acyl‐CoA Dehydrogenase Deficiency (MADD) is an autosomal recessive inborn error of metabolism caused by biallelic pathogenic variants in one of three known genes: ETFA, ETFB, and ETFDH. It can cause multisystem dysfunction, including cardiomyopathy in severe cases.
Yutaka Furuta, Kaitlyn N. Bloom, Jerry Vockley, Angela R. Grochowsky, Neena S. Agrawal, Ellen W. Strickler, Natalie N. Owen, Erica T. Gray, B. Lakshitha A. Perera, Eric R. Gamazon, Lynette C. Rives, Hua‐Chang Chen, Qi Liu, Rizwan Hamid, Joy D. Cogan, John A. Phillips III, Thomas A. Cassini, Bryce A. Schuler   +17 more
wiley   +1 more source

Development and Quality Evaluation of Fiber‐Enriched Pasta Incorporating Green Banana Flour and Whole Wheat Flour: Physicochemical, Antioxidant, and Sensory Properties

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
This study developed fiber‐enriched pasta by incorporating green banana flour and whole wheat flour and evaluated its nutritional, physicochemical, antioxidant, and sensory properties. Enrichment increased protein, dietary fiber, calcium, and iron contents, while DPPH radical‐scavenging activity reached 95.7%.
Shariful Islam, Nusrat Sadia Himu, Md. Faridul Islam, Amena Kibria, Mohammad Nazrul Islam Bhuiyan, Md. Jaynal Abedin, Md. Nuruddin Miah, Md. Abdus Satter Miah   +7 more
wiley   +1 more source

Carvacrol Mitigates TNF‐α‐Driven Oxidative and Bioenergetic Impairment in L6 Rat Myoblasts

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
Carvacrol (6.25 µg/mL) attenuates TNF‐α‐induced bioenergetic toxicity in L6 rat myoblasts by reducing LDH release by 79%, quenching intracellular ROS, partially restoring mitochondrial membrane potential and ion‐dependent ATPase activities, recovering catalase and SOD function, and upregulating SIRT1 and AMPK mRNA—identifying carvacrol as a multi ...
Ali M. Albarrati, Rakan I. Nazer
wiley   +1 more source

Mechanistic Insights Into Hepatotoxicity‐Induced Liver Cirrhosis and Anemia: Iron Dysregulation, the Hepcidin–Ferroportin Axis, and Emerging Therapeutic Strategies

Organ Medicine, Volume 3, Issue 3, Page 171-185, September 2026.
Patients with alcohol‐associated liver cirrhosis or acetaminophen (APAP) toxicity frequently develop anemia with iron metabolism disturbances. Dysregulation of hepcidin–ferroportin signaling, along with inflammation, oxidative stress, hypoxia, impaired intestinal iron absorption, malnutrition, and gastrointestinal bleeding, contributes to anemia ...
Debabrata Dash, Raj Kumar Koiri
wiley   +1 more source

Revealing Functional Traits of Insect Pest Suppressive Rhizobacterial Strains Through Comparative Genomics

Environmental Microbiology, Volume 28, Issue 9, September 2026.
Inoculation of select rhizobacterial strains to enhance crop health is a growing field in sustainable agriculture. This study conducts a comparative genomic analysis of five plant‐beneficial rhizobacterial strains (Acidovorax radicis N35, Bacillus subtilis B171, Bacillus velezensis FZB42 Rhizobium radiobacter F4 and Pseudomonas simiae WCS417r ...
Edward C. Cairns, Francesco Del Carratore, James P. J. Hall, Sharon E. Zytynska   +3 more
wiley   +1 more source