Results 151 to 160 of about 433,059 (284)

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

FEBS Open Bio, Volume 15, Issue 7, Page 1159-1175, July 2025.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli, Andrea Spinaci, Cui Chang, Rosaria Volpini, Catia Lambertucci, Matteo Landriscina, Vincenza Conteduca, Consuelo Amantini, Cristina Aguzzi, Laura Zeppa, Martina Giangrossi, Laura Soverchia, Matteo Santoni, Massimo Nabissi, Giorgio Santoni, Carlo Polidori   +15 more
wiley   +1 more source

Long Non-Coding RNAs and RNA-Binding Proteins in Pancreatic Cancer Development and Progression. [PDF]

Cancers (Basel)
Preckwinkel P, Mir KUI, Otto FW, Elrewany H, Sinz A, Hüttelmaier S, Bley N, Gutschner T.   +7 more
europepmc   +1 more source

Primary structure of tRNAval2 from brewer's yeast [PDF]

, 1971
Bonnet, J., Dirheimer, G., Ebel, J.P.
core   +1 more source

STOX1 Isoform A Promotes Proliferation and Progression of Hepatocellular Carcinoma by Dual Mechanisms of Transcriptionally Upregulation of Cyclin B1 and Activation of ROS‐Dependent PTEN/AKT1 Signaling

Cancer Medicine, Volume 14, Issue 13, July 2025.
ABSTRACT Background Dysregulation of transcription factors is one of the most common factors for the pathogenesis of hepatocellular carcinoma (HCC). To the best of our knowledge, no study has yet investigated the clinical significance and functional role of STOX1 in HCC. Methods Real‐time PCR, Western blotting and immunohistochemistry were performed to
Chunlin Jiang, Chong Wang, Jian Ao, Yangping Liu, Fengjie Sun, Wangpan Shi, Zeyi Guo, Yanping Wu, Luxiang Gan, Meimei Wu, Yaofeng Zhi, Zijie Meng, Wanting Wu, Juanhua Wu, Yong Ye, Xin Zhang, Dong Ren, Mingxin Pan   +17 more
wiley   +1 more source

Exosomal miRNAs in pancreatitis: Mechanisms and potential applications (Review). [PDF]

Mol Med Rep
Wang L, Zhang J, He Z, Kong X, Liu C, Xia Y, Yang M, Wang K.   +7 more
europepmc   +1 more source

Small Nucleolar RNAs: Biological Functions and Diseases

MedComm, Volume 6, Issue 7, July 2025.
The majority of snoRNAs are derived from the intron region of genes, besides to intronic snoRNAs, some snoRNAs are transcribed as independent genes, often by Pol II or III, these snoRNAs are called intergenic snoRNAs. All of these play a role in the occurrence and progression of various diseases through multiple functions.
Yi Wang, Min Fu, Zaiyong Zheng, Jianguo Feng, Chunxiang Zhang   +4 more
wiley   +1 more source

Transfer RNA-derived small RNA serves as potential non-invasive diagnostic marker and a novel therapeutic target for acute pancreatitis. [PDF]

World J Gastroenterol
Zhang J, Ou CL.
europepmc   +1 more source

A comparison of the primary structures of the 16 S ribosomal RNAs from Escherichia coli and Proteus vulgaris [PDF]

, 1970
Ebel, J.P., Fellner, P., Fischel, J.L.
core   +1 more source

Conserved structural topologies in RNase A-like and trypsin-like serine proteases: a sequence-based folding analysis. [PDF]

BMC Mol Cell Biol
Kabir KMA, Takahashi T, Kikuchi T.
europepmc   +1 more source

Structural features for the mechanism of antitumor action of a dimeric human pancreatic ribonuclease variant

Protein Science, 2008
A. Merlino, G. Avella, S. Di Gaetano, Angela Arciello, R. Piccoli, L. Mazzarella, F. Sica   +6 more
semanticscholar   +1 more source