The role of RNA editing in cancer development and metabolic disorders [PDF]
Kung, Che-Pei+2 more
core +2 more sources
Phase Separation Regulates Metabolism, Mitochondria, and Diseases
Mitochondrion‐related liquid–liquid phase separation. (1) Phase separation mediates the self‐assembly of mitochondrial nucleoids (mt‐nucleoids). (2) Phase segregation mediates the formation of mitochondrial RNA granules (MRGs). (3) Phase separation mediates the formation of mitochondrial degradosomes.
Chuan Gao+3 more
wiley +1 more source
Pancreatic Comorbidities in Pediatric Celiac Disease: Exocrine Pancreatic Insufficiency, Pancreatitis, and Diabetes Mellitus. [PDF]
Poddighe D.
europepmc +1 more source
Nascent polypeptide chains on mitochondrial ribosomes and their integration into the inner membrane [PDF]
Kroon, Albertus M.+3 more
core
In hepatocellular carcinoma (HCC), the methyltransferase NSUN6 catalyzes m⁵C modification of BMPER mRNA, enhancing its stability and elevating BMPER protein expression. This NSUN6‐BMPER axis suppresses HCC progression by inhibiting tumor cell proliferation/migration while correlating with improved patient prognosis, establishing RNA epigenetic ...
Chunlin Liu+7 more
wiley +1 more source
Effect of Maternal Hyperglycemia on Fetal Pancreatic Islet Development. [PDF]
Dias CP+6 more
europepmc +1 more source
PTBP1 and Cancer: From RNA Regulation to Therapeutic Potential
ABSTRACT Polypyrimidine tract binding protein 1 (PTBP1) belongs to the heterogeneous nuclear ribonucleoprotein (hnRNP) family and is a widely studied RNA‐binding protein involved in regulating mRNA splicing, stability, localization, and translation. In addition, PTBP1 can participate in various non‐coding RNA action processes and affect tumorigenesis ...
Chengdong Ji+6 more
wiley +1 more source
DICER1: The Argonaute Endonuclease Family Member and Its Role in Pediatric and Youth Pathology. [PDF]
Sergi CM, Minervini F.
europepmc +1 more source
Dad's legacy: Epigenetic reprogramming and paternal inflammatory memory in offspring health
Abstract Over the past decade, numerous reports have highlighted intergenerational and even transgenerational epigenetic effects resulting from parental exposure to diets, toxins, and stress. In many cases, these parentally induced phenotypes do not seem to confer an obvious benefit, making it challenging to understand the evolutionary drivers behind ...
Shamila D. Alipoor+3 more
wiley +1 more source
Lipotoxicity: A New Perspective in Type 2 Diabetes Mellitus. [PDF]
Chen B+7 more
europepmc +1 more source