Results 161 to 170 of about 433,059 (284)

Phase Separation Regulates Metabolism, Mitochondria, and Diseases

open access: yesMedComm, Volume 6, Issue 7, July 2025.
Mitochondrion‐related liquid–liquid phase separation. (1) Phase separation mediates the self‐assembly of mitochondrial nucleoids (mt‐nucleoids). (2) Phase segregation mediates the formation of mitochondrial RNA granules (MRGs). (3) Phase separation mediates the formation of mitochondrial degradosomes.
Chuan Gao   +3 more
wiley   +1 more source

Nascent polypeptide chains on mitochondrial ribosomes and their integration into the inner membrane [PDF]

open access: yes, 1974
Kroon, Albertus M.   +3 more
core  

NSUN6 Maintains BMPER Stability in an m5C‐Dependent Manner to Suppress Cell Proliferation and Migration in Hepatocellular Carcinoma

open access: yesBiology of the Cell, Volume 117, Issue 7, July 2025.
In hepatocellular carcinoma (HCC), the methyltransferase NSUN6 catalyzes m⁵C modification of BMPER mRNA, enhancing its stability and elevating BMPER protein expression. This NSUN6‐BMPER axis suppresses HCC progression by inhibiting tumor cell proliferation/migration while correlating with improved patient prognosis, establishing RNA epigenetic ...
Chunlin Liu   +7 more
wiley   +1 more source

Effect of Maternal Hyperglycemia on Fetal Pancreatic Islet Development. [PDF]

open access: yesBiology (Basel)
Dias CP   +6 more
europepmc   +1 more source

PTBP1 and Cancer: From RNA Regulation to Therapeutic Potential

open access: yesJournal of Cellular and Molecular Medicine, Volume 29, Issue 13, July 2025.
ABSTRACT Polypyrimidine tract binding protein 1 (PTBP1) belongs to the heterogeneous nuclear ribonucleoprotein (hnRNP) family and is a widely studied RNA‐binding protein involved in regulating mRNA splicing, stability, localization, and translation. In addition, PTBP1 can participate in various non‐coding RNA action processes and affect tumorigenesis ...
Chengdong Ji   +6 more
wiley   +1 more source

Dad's legacy: Epigenetic reprogramming and paternal inflammatory memory in offspring health

open access: yesJournal of Internal Medicine, Volume 298, Issue 1, Page 16-30, July 2025.
Abstract Over the past decade, numerous reports have highlighted intergenerational and even transgenerational epigenetic effects resulting from parental exposure to diets, toxins, and stress. In many cases, these parentally induced phenotypes do not seem to confer an obvious benefit, making it challenging to understand the evolutionary drivers behind ...
Shamila D. Alipoor   +3 more
wiley   +1 more source

Lipotoxicity: A New Perspective in Type 2 Diabetes Mellitus. [PDF]

open access: yesDiabetes Metab Syndr Obes
Chen B   +7 more
europepmc   +1 more source

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