Results 11 to 20 of about 132,332 (305)

A novel double-ribonuclease toxin-antitoxin system linked to the stress response and survival of Acidovorax citrulli

Microbiology Spectrum, 2023
Toxin-antitoxin (TA) systems are widespread among prokaryotes and can play an important role in the maintenance of genetic elements and pathogen virulence.
Xudong Wang, Yumin Kan, Kaihong Bai, Xiaoli Xu, Xing Chen, Chengxuan Yu, Jia Shi, Na Jiang, Jianqiang Li, Laixin Luo   +9 more
doaj   +1 more source

Protein disulfide-isomerase interacts with a substrate protein at all stages along its folding pathway [PDF]

, 2014
In contrast to molecular chaperones that couple protein folding to ATP hydrolysis, protein disulfide-isomerase (PDI) catalyzes protein folding coupled to formation of disulfide bonds (oxidative folding).
A Jansens, A Land, A Pirneskoski, A. Katrine Wallis, Alistair G. Irvine, AR Karala, AR Karala, AY Denisov, B van den Berg, B van den Berg, B van den Berg, CB Anfinsen, Claudia A. Blindauer, CPM van Mierlo, CPM van Mierlo, CW Gruber, DP Goldenberg, E van Anken, F Hatahet, G Kozlov, G Wagner, HC Shin, HC Shin, J Riemer, JH Laity, JL Arolas, JS Weissman, JS Weissman, L Wang, LJ Byrne, Lloyd W. Ruddock, M Narayan, Mark J. Howard, Michelle L. Rowe, Narinder Sanghera, NJ Bulleid, NJ Darby, P Klappa, P Venetianer, RA Williamson, RB Freedman, RF Goldberger, Richard A. Williamson, RJ Ellis, Robert B. Freedman, S Masui, S Talluri, Salvador Ventura, TE Creighton, TE Creighton, TE Creighton, TE Creighton, VD Nguyen, VD Nguyen, WF Vranken   +54 more
core   +9 more sources

Mammalian mitochondrial RNAs are degraded in the mitochondrial intermembrane space by RNASET2

Protein & Cell, 2017
Mammalian mitochondrial genome encodes a small set of tRNAs, rRNAs, and mRNAs. The RNA synthesis process has been well characterized. How the RNAs are degraded, however, is poorly understood. It was long assumed that the degradation happens in the matrix
Peipei Liu, Jinliang Huang, Qian Zheng, Leiming Xie, Xinping Lu, Jie Jin, Geng Wang   +6 more
doaj   +1 more source

Specific antibodies against binase: Preparation and application

Учёные записки Казанского университета: Серия Естественные науки, 2021
Secreted ribonuclease of Bacillus pumilus (binase) is a promising antitumor agent with established selective cytotoxicity against various types of cancer cells expressing specific oncogenes.
V.I. Vershinina, E.V. Dudkina, V.V. Ulyanova, V.A. Kalashnikov, O.N. Ilinskaya   +4 more
doaj   +1 more source

Mitochondrial Translation Products before and after Integration into the Mitochondrial Membrane in Neurospora crassa [PDF]

, 1972
# 1. Nascent translation products on mitochondrial ribosomes were selectively labeled in vivo in the presence of cycloheximide with radioactive leucine. They were isolated together with the ribosomes. # 2.
Michel, Rainer, Neupert, Walter
core   +1 more source

Structural–Functional Relationship of the Ribonucleolytic Activity of aIF5A from Sulfolobus solfataricus

Biomolecules, 2022
The translation factor IF5A is a highly conserved protein playing a well-recognized and well-characterized role in protein synthesis; nevertheless, some of its features as well as its abundance in the cell suggest that it may perform additional functions
Alice Romagnoli, Paolo Moretti, Mattia D’Agostino, Jesmina Rexha, Nunzio Perta, Astra Piccinini, Daniele Di Marino, Francesco Spinozzi, Anna La Teana   +8 more
doaj   +1 more source

Effect of osmotic stress on in vitro translational capacity of polysomes and on the composition of polysome-associated proteins in germinating seeds of pea (Pisum sativum L.)

Acta Societatis Botanicorum Poloniae, 2012
Plant growth throughout the world is often limited by unfavourable environmental conditions. This paper reports results of a study on long- and short-term osmotic stress (−0.5 MPa) followed by a recovery on in vitro translational capacity of polysomes ...
Wioletta Brosowska-Arendt, Stanisław Weidner   +1 more
doaj   +1 more source

Identification of Crucial Amino Acid Residues for Antimicrobial Activity of Angiogenin 4 and Its Modulation of Gut Microbiota in Mice

Frontiers in Microbiology, 2022
Angiogenin 4 bearing ribonuclease activity is an endogenous antimicrobial protein expressed in small and large intestine. However, the crucial amino acid residues responsible for the antibacterial activity of Ang4 and its impact on gut microbiota remain ...
Mst. Farzana Sultana, Mst. Farzana Sultana, Maki Suzuki, Fumiya Yamasaki, Wataru Kubota, Kohta Takahashi, Hirohito Abo, Hiroto Kawashima   +7 more
doaj   +1 more source

RNase Y Autoregulates Its Synthesis in Bacillus subtilis

Microorganisms, 2023
The instability of messenger RNA is crucial to the control of gene expression. In Bacillus subtilis, RNase Y is the major decay-initiating endoribonuclease.
Anna Korobeinikova, Soumaya Laalami, Clément Berthy, Harald Putzer   +3 more
doaj   +1 more source

Synthesis and evaluation of troponoids as a new class of antibiotics [PDF]

, 2018
Novel antibiotics are urgently needed. The troponoids [tropones, tropolones, and α-hydroxytropolones (α-HT)] can have anti-bacterial activity. We synthesized or purchased 92 troponoids and evaluated their antibacterial activities against Staphylococcus ...
Adegboyega, Patrick, Cao, Feng, Donlin, Maureen J., Elagawany, Mohamed, Elgendy, Bahaa, Meyers, Marvin J., Murelli, Ryan P., Orth, Cari, Tavis, John E.   +8 more
core   +4 more sources