Results 21 to 30 of about 156,401 (384)
Structural insight into precursor ribosomal RNA processing by ribonuclease MRP
Science, 2020 Adapted to the task at hand RNA-based catalysts perform fundamental tasks in cellular RNA metabolism, especially in eukaryotes, where RNAs are cut by specialized ribonucleoproteins (RNPs) as part of ribosome assembly or messenger RNA regulation or ...
P. Lan +6 more
semanticscholar +1 more source
Human and mouse angiogenins: Emerging insights and potential opportunities
Frontiers in Microbiology, 2022 Angiogenin, a well-known angiogenic factor, is crucial to the angiogenesis in gastrointestinal tumors. Human angiogenin has only one gene, whereas the murine angiogenin family has extended to incorporate six genes.
Mst. Farzana Sultana +3 more
doaj +1 more source
The compactness of ribonuclease A and reduced ribonuclease A
FEBS Letters, 1998 The compactness of ribonuclease A with intact disulfide bonds and reduced ribonuclease A was investigated by synchrotron small‐angle X‐ray scattering. The R g values and the Kratky plots showed that non‐reduced ribonuclease A maintain a compact shape with a R g value of about 17.3 Å in 8 M urea.
Ying Xin Fan +4 more
openaire +3 more sources
Chem. Commun., 2011 The S-peptide and S-protein components of bovine pancreatic ribonuclease form a noncovalent complex with restored ribonucleolytic activity. Although this archetypal protein-fragment complementation system has been the object of historic work in protein chemistry, intrinsic limitations compromise its utility.
Rex W. Watkins +2 more
openaire +3 more sources
An ancient evolutionary connection between Ribonuclease A and EndoU families
RNA: A publication of the RNA Society, 2020 The ribonuclease A family of proteins is well studied from the biochemical and biophysical points of view, but its evolutionary origins are obscure, as no sequences homologous to this family have been reported outside of vertebrates.
A. Mushegian +3 more
semanticscholar +1 more source
Acta Societatis Botanicorum Poloniae, 2012 Plant growth throughout the world is often limited by unfavourable environmental conditions. This paper reports results of a study on long- and short-term osmotic stress (−0.5 MPa) followed by a recovery on in vitro translational capacity of polysomes ...
Wioletta Brosowska-Arendt +1 more
doaj +1 more source
Ribonucleases as potential therapeutic agents [PDF]
مجله بیوتکنولوژی کشاورزی, 2021 Objective Due to high cytotoxicity effect, ribonucleases (RNases) are known as pharmacological agents with therapeutic potential. The high potential of these enzymes in the destruction of RNA strand and their other substrates and subsequently, cell ...
Masoume Vakili-Azghandi +3 more
doaj +1 more source
Mammalian mitochondrial RNAs are degraded in the mitochondrial intermembrane space by RNASET2
Protein & Cell, 2017 Mammalian mitochondrial genome encodes a small set of tRNAs, rRNAs, and mRNAs. The RNA synthesis process has been well characterized. How the RNAs are degraded, however, is poorly understood. It was long assumed that the degradation happens in the matrix
Peipei Liu +6 more
doaj +1 more source
Inhibition of IRE1α-mediated XBP1 mRNA cleavage by XBP1 reveals a novel regulatory process during the unfolded protein response [PDF]
, 2017 Background: The mammalian endoplasmic reticulum (ER) continuously adapts to the cellular secretory load by the activation of an unfolded protein response (UPR).
Bulleid, Neil J. +4 more
core +2 more sources
Histone deacetylase 2-mediated deacetylation of the Ribonuclease 1 promoter in inflamed human endothelial cells [PDF]
, 2020 Endothelial cells (ECs) function as protective barrier to separate the blood from the surrounding tissue by conducting crucial roles in regulation and maintenance of vascular homeostasis, such as control of vessel permeability or coagulation.
Bedenbender, Katrin
core +1 more source