Results 201 to 210 of about 34,862 (253)

Intratumoral Hypoxia Triggers Mitochondrial BHLHE40 ROS Sensing Pathway to Promote Radioresistance in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
Hypoxia triggers a dual mechanism for BHLHE40 upregulation: reactive oxygen species (ROS)‐dependent post‐translational modification and hypoxia‐inducible factor (HIF)‐dependent transcriptional activation. Under hypoxic conditions, mitochondrial BHLHE40 accumulates and senses ROS via cysteine thiol oxidation and disulfide‐linked homodimer formation ...
Jia Liu   +13 more
wiley   +1 more source

Pan-S-locus analysis reveals insights into the origin and evolution of self-incompatibility in the orange subfamily. [PDF]

open access: yesGenome Biol
Hu J   +13 more
europepmc   +1 more source

Advances in antisense oligonucleotide treatment for cancer. [PDF]

open access: yesJpn J Clin Oncol
Zhu L, Muhtar P, Goyama S, Yoshimi A.
europepmc   +1 more source

Allosteric activation mechanism of the type VII CRISPR-Cas system. [PDF]

open access: yesNucleic Acids Res
Zhang S   +9 more
europepmc   +1 more source

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