Results 221 to 230 of about 19,244,439 (340)
Advanced Science, EarlyView.A gastrula‐premarked enhancer within the first intron of Cdx2 governs posterior embryonic development via both regulating Cdx2 expression in cis and coordinating TGF‐β signaling in trans to ensure proper posterior body development. Functional rescue in gastruloids reveals a Cdx2‐independent pathway, highlighting p‐Enh‐eRNA as key epigenetic ...
Yingying Chen +16 more
wiley +1 more source
Cytokine Storm Induction Linked to Multi‐Organ Failure in Fatal Jellyfish Stings
Advanced Science, EarlyView.N. nomurai is the most important injurious species in the coastal area of China. Model construction, omics analysis, mechanism exploration, and intervention measures of N. nomurai envenomation are performed in the current study, and it suggested that cytokine storm played an important role in pathogenesis.
Yichao Wang +15 more
wiley +1 more source
Analysis of the gene encoding the RNA subunit of ribonuclease P from cyanobacteria [PDF]
, 1992 Agustı́n Vioque
openalex +1 more source
A Distinct Binding Mode of Archaeal Ribonuclease P Proteins to RNA
Bioscience, biotechnology and biochemistry, 2012 Masato Ishihara +4 more
semanticscholar +1 more source
Identification and analysis of ribonuclease P and MRP RNA in a broad range of eukaryotes
, 2005 Paolo Piccinelli
openalex +1 more source
Advanced Science, EarlyView.The study found that RPL6 is frequently upregulated in HCC tissues with extrahepatic metastasis. Elevated RPL6 bound to and increased the stability of HMGCS1 mRNA, thereby enhancing intracellular cholesterol levels. Subsequently, increased cholesterol promotes cancer metastasis in HCC by stabilizing HIF‐1α protein.
Minli Yang +15 more
wiley +1 more source
Human Schlafen 14 Cleavage of Short Double‐Stranded RNAs Underpins its Antiviral Activity
Advanced Science, EarlyView.SLFN14 is associated with human diseases. SLFN14 is found to cleave RNAs containing short duplexes. The cryo‐EM structures of SLFN14 and SLFN14‐hairpin RNA complex reveal that SLFN14 assembles into a ring‐like dimer; two RNase domains form an RNA‐binding groove accommodating a hairpin RNA.
Mengyun Li +8 more
wiley +1 more source
Ribonuclease-P RNA Gene of the Plastid Chromosome from Cyanophora Paradoxa [PDF]
, 1995 Evgeni L. Shevelev +3 more
openalex +1 more source
Advanced Science, EarlyView.This study demonstrates that mutant FAT1 promotes ASCL2‐driven, CPT1A‐dependent fatty acid oxidation, leading to resistance to CPI‐613‐mediated TCA cycle inhibition in head and neck cancer. In vivo gene depletion of mutant FAT1 with LNP‐sgFAT1 suppresses tumor growth and restores CPI‐613 sensitivity, revealing a targetable metabolic bypass with ...
Fanghui Chen +11 more
wiley +1 more source
Crystal Structures of Archaeal Ribonuclease P Proteins
, 2007 Yoshimitsu Kakuta, Makoto Kimura
openalex +2 more sources