Results 181 to 190 of about 139,231 (236)
Recent Advances in Xenes Based FET for Biosensing Applications
Xenes (monoelemental 2D materials like graphene, phosphorene, tellurene) enable ultrasensitive FET (Field‐Effect Transistor) biosensors due to their tunable bandgap, high carrier mobility, and large surface area. Advances in synthesis (CVD, MBE) and functionalization allow detection of DNA/RNA (via CRISPR‐Cas systems), proteins, small molecules, and ...
Huide Wang+9 more
wiley +1 more source
Human U1 and U2 small nuclear ribonucleoproteins contain common and unique polypeptides
C. Kinlaw, S. Dusing-Swartz, S. Berget
semanticscholar +1 more source
ABSTRACT HNRNPU‐related neurodevelopmental disorder (HNRNPU‐NDD) is caused by pathogenic and likely pathogenic variants in HNRNPU. With increasing accessibility to advanced genetic investigations, children presenting with developmental delay and intellectual disability will often undergo genomic testing; hence, the number of patients found to be ...
A. K. O. Hodgson+14 more
wiley +1 more source
Abstract CEP162, a 162‐kDa centrosome protein, is a crucial centrosomal adapter, mediating cell differentiation and polarization. CEP162 maintains mitosis by dynamically stabilizing microtubules. CEP162 promotes the transition zone (TZ) assembly in the basal body through interaction with CEP131, CEP290, and axoneme microtubules as well as the distal ...
Jun Yin+7 more
wiley +1 more source
L. D. Fresco, M. Kurilla, J. Keene
semanticscholar +1 more source
Phase Separation: A New Dimension to Understanding Tumor Biology and Therapy
Liquid–liquid phase separation (LLPS) facilitates the assembly of biomolecular condensates by leveraging weak multivalent interactions. The low‐complexity domains, foldable domains of proteins, and nucleic acids provide multivalent interaction sites among different molecules and contribute to the formation of condensates.
Xingwen Wang+4 more
wiley +1 more source
Ji-Long Liu, J. Gall
semanticscholar +1 more source
Oxidative Stress in Antigen Processing and Presentation
Reactive oxygen species (ROS) play a crucial role in antigen processing and presentation, essential for linking innate and adaptive immunity. While balanced ROS levels promote immune function, excess ROS can disrupt antigen recognition, resulting in immune dysfunction.
Qinxia Chang+9 more
wiley +1 more source
CXXC5 is a ubiquitinated protein and is degraded by the ubiquitin‐proteasome pathway
Abstract CXXC5, as a member of the zinc‐finger CXXC family proteins, interacts with unmodified CpG dinucleotides to modulate the expression of genes involved in cellular proliferation, differentiation, and death in physiology and pathophysiology. Various signaling pathways, including mitogenic 17β‐estradiol (E2), contribute to the expression and ...
Hazal Ayten+10 more
wiley +1 more source