A genome‐wide CRISPR‐Cas9‐based genetic screen in cisplatin‐resistant NSCLC cells revealed 63 potential candidate genes for overcoming cisplatin resistance, including GPR89A. GPR89A, localised in the Golgi, modulates voltage‐gated anion channel activity and is involved in intracellular pH reduction.
Hale Guler Kara+9 more
wiley +1 more source
The stability, polyadenylic acid content and ribonucleoprotein form of nulcear ribonucleic acid in artichoke [PDF]
K.S.R. Chapman, John Ingle
openalex +1 more source
Accelerating Cleavage Activity of CRISPR-Cas13 System on a Microfluidic Chip for Rapid Detection of RNA. [PDF]
Kim J+9 more
europepmc +1 more source
The quest for the best target genes for RNAi‐mediated pest control
A major challenge for RNAi mediated pest control is the identification of the most effective RNAi target genes from the pool of ~37% of all genes that are essential. Effective RNAi target genes are predominantly highly conserved genes serving basic cellular functions such as protein degradation.
Doga Cedden, Gregor Bucher
wiley +1 more source
An electron microscope study of extranucleolar ribonucleoprotein bodies in the microspore of Larix europea L. [PDF]
A. Górska-Brylass, Bogdan Wróbel
openalex +1 more source
ABSTRACT Background People with intellectual disability suffer complex challenges due to adaptive functioning limitations, high rates of chronic diseases and shortened lifespans compared with the general population. Telomere shortening is a hallmark of ageing, and short telomeres are linked to neurological disorders.
Sarah M. Hanley+3 more
wiley +1 more source
Effect of homopolyribonucleotides on messenger ribonucleoprotein particles [PDF]
Bo Sundquist, Torgny Persson
openalex +1 more source
Splice it hot: How nuclear PP2A B'η regulates splicing fidelity by targeting the heat-stressed spliceosome. [PDF]
Wang J.
europepmc +1 more source
Incorporation of ribonucleic acid in vitro into dense ribonucleoprotein-like materials by isolated rat liver nuclei [PDF]
Iwao Suzuka
openalex +1 more source
Proteomic profiling of pseudorabies virus-infected PK-15 cells based on 4D label free analysis. [PDF]
Wang S+5 more
europepmc +1 more source