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Shock-Induced Degradation of Guanosine and Uridine Promoted by Nickel and Carbonate: Potential Applications [PDF]

open access: yesMolecules, 2023
Experimental studies of the degradation of two ribonucleosides (guanosine and uridine) were carried out by making use of mechanochemistry. Mechanochemical experiments reveal the decomposition of guanosine and uridine, promoted by nickel(II) and carbonate
Gustavo P. Maia   +3 more
doaj   +2 more sources

Partition Chromatography on Starch of Ribonucleosides [PDF]

open access: bronzeNature, 1948
DURING work on ribonucleic acid turnover with nitrogen-15 in this Department, we found it necessary to isolate the different nitrogen-containing substances from small amounts of ribonucleic acid. It was thought that partition chromatography on starch as introduced by Elsden and Synge1 might give a possible solution to our problem. Vischer and Chargaff2
Peter Reichard
openalex   +3 more sources

Quantifying the mRNA epitranscriptome reveals epitranscriptome signatures and roles in cancer [PDF]

open access: yesCellular and Molecular Life Sciences
Post-transcriptional modifications on mRNA are crucial for mRNA fate and function. The current lack of a comprehensive method for high-coverage and sensitive quantitative analysis of mRNA modifications significantly limits the discovery of new mRNA ...
Ying Feng   +11 more
doaj   +2 more sources

Ribonucleoside Hydrolases–Structure, Functions, Physiological Role and Practical Uses [PDF]

open access: yesBiomolecules, 2023
Ribonucleoside hydrolases are enzymes that catalyze the cleavage of ribonucleosides to nitrogenous bases and ribose. These enzymes are found in many organisms: bacteria, archaea, protozoa, metazoans, yeasts, fungi and plants.
Leonid A. Shaposhnikov   +3 more
doaj   +2 more sources

Characterizing Benzo[a]pyrene Adducts in Transfer RNAs Using Liquid Chromatography Coupled with Tandem Mass Spectrometry (LC-MS/MS) [PDF]

open access: yesBiomedicines, 2023
The activated forms of the environmental pollutant benzo[a]pyrene (B[a]P), such as benzo[a]pyrene diol epoxide (BPDE), are known to cause damage to genomic DNA and proteins. However, the impact of BPDE on ribonucleic acid (RNA) remains unclear.
Cassandra Herbert   +4 more
doaj   +2 more sources

Response of Escherichia coli chemotaxis pathway to pyrimidine deoxyribonucleosides [PDF]

open access: yesMicrobiology Spectrum
Nucleosides are essential components of all living cells. Bacteria use salvage pathways to import nucleosides from their environment and to utilize them for nucleic acid biosynthesis, but also as alternative sources of carbon, nitrogen and energy. Motile
Malay Shah, Wenhao Xu, Victor Sourjik
doaj   +2 more sources

Practical Silyl Protection of Ribonucleosides [PDF]

open access: greenOrganic Letters, 2013
Herein we report the site-selective silylation of the ribonucelosides. The method enables a simple and efficient procedure for accessing suitably protected monomers for automated RNA synthesis. Switching to the opposite enantiomer of the catalyst allows for the selective silylation of the 3'-hydroxyl, which could be used in the synthesis of unnatural ...
Thomas P. Blaisdell   +4 more
openalex   +3 more sources

Deoxyribo‐ and Ribonucleoside H‐Phosphonates [PDF]

open access: bronzeCurrent Protocols in Nucleic Acid Chemistry, 2001
AbstractMost methods for preparing H‐phosphonate monoesters suffer from variable yields and are often incompatible with common protecting groups used in oligonucleotide synthesis. This unit describes four procedures that consistently give high yields of the desired products.
Jacek Stawiński, Roger Strömberg
openalex   +5 more sources

Novel Antimicrobial Activities of Albofungin, Albonoursin, and Ribonucleosides Produced by Streptomyces sp. Caat 5-35 Against Phytopathogens and Their Potential as a Biocontrol Agent [PDF]

open access: yesMolecules
The genus Streptomyces is the largest group within the phylum Actinobacteria, recognized for producing antibiotics and enzymes, with wide applications in medicine and biological control for crop protection against phytopathogens.
Carmen Julia Pedroza-Padilla   +4 more
doaj   +2 more sources

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