Shock-Induced Degradation of Guanosine and Uridine Promoted by Nickel and Carbonate: Potential Applications [PDF]
Molecules, 2023 Experimental studies of the degradation of two ribonucleosides (guanosine and uridine) were carried out by making use of mechanochemistry. Mechanochemical experiments reveal the decomposition of guanosine and uridine, promoted by nickel(II) and carbonate
Gustavo P. Maia +3 more
doaj +2 more sources
Frontiers in Molecular Biosciences, 2021 RNA methylation plays a significant regulatory role in various of physiological activities and it has gradually become a hotspot of epigenetics in the past decade.
Kailun Xu, Shu Zheng, Cheng Guo
exaly +3 more sources
Ribonucleoside Hydrolases–Structure, Functions, Physiological Role and Practical Uses [PDF]
Biomolecules, 2023 Ribonucleoside hydrolases are enzymes that catalyze the cleavage of ribonucleosides to nitrogenous bases and ribose. These enzymes are found in many organisms: bacteria, archaea, protozoa, metazoans, yeasts, fungi and plants.
Leonid A. Shaposhnikov +3 more
doaj +2 more sources
The taste of ribonucleosides: Novel macronutrients essential for larval growth are sensed by Drosophila gustatory receptor proteins [PDF]
PLoS Biology, 2018 Animals employ various types of taste receptors to identify and discriminate between different nutritious food chemicals. These macronutrients are thought to fall into 3 major groups: carbohydrates/sugars, proteins/amino acids, and fats.
Hubert Amrein
exaly +2 more sources
Characterizing Benzo[a]pyrene Adducts in Transfer RNAs Using Liquid Chromatography Coupled with Tandem Mass Spectrometry (LC-MS/MS) [PDF]
Biomedicines, 2023 The activated forms of the environmental pollutant benzo[a]pyrene (B[a]P), such as benzo[a]pyrene diol epoxide (BPDE), are known to cause damage to genomic DNA and proteins. However, the impact of BPDE on ribonucleic acid (RNA) remains unclear.
Cassandra Herbert +4 more
doaj +2 more sources
PLoS Pathogens, 2012 Ribonucleoside analogues have potential utility as anti-viral, -parasitic, -bacterial and -cancer agents. However, their clinical applications have been limited by off target effects.
Jamie J Arnold +2 more
exaly +3 more sources
Ribonucleosides, Aminoacyl- and Peptidyl-RNA: Synthesis, Thermodynamics, and Structure
CHIMIA, 1999 Ribonucleosides, RNA and peptides are prepared to study non-covalent interactions of RNA, aminoacyl- and peptidyl-RNA. Techniques used include chemical synthesis in solution and on solid supports, UV- and NM-detected thermal denaturation, X-ray ...
Ewa Biala +3 more
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Engineering a Bifunctional Fusion Purine/Pyrimidine Nucleoside Phosphorylase for the Production of Nucleoside Analogs [PDF]
BiomoleculesNucleoside phosphorylases (NPs) are pivotal enzymes in the salvage pathway, catalyzing the reversible phosphorolysis of nucleosides to produce nucleobases and α-D-ribose 1-phosphate.
Daniel Hormigo +4 more
doaj +2 more sources
An Efficient and Short Route for the Synthesis of Reverse Pyrrole Ribonucleosides
Journal of the Brazilian Chemical Society, 2002 The synthesis of reverse pyrrole ribonucleosides methyl 5-C-(4-acetyl-5-methyl-pyrrol-1-yl)-2,3-O-isopropylidene-5-deoxy- beta-D-ribofuranoside (10), methyl 5-C-(4-ethoxycarbonyl-5-methyl-pyrrol-1-yl)-2,3-O-isopropylidene-5-deoxy- beta-D-ribofuranoside ...
Pereira Letícia O. R. +3 more
doaj +2 more sources
Efficient Biocatalytic Synthesis of Dihalogenated Purine Nucleoside Analogues Applying Thermodynamic Calculations [PDF]
, 2020 The enzymatic synthesis of nucleoside analogues has been shown to be a sustainable and efficient alternative to chemical synthesis routes. In this study, dihalogenated nucleoside analogues were produced by thermostable nucleoside phosphorylases in ...
Giessmann, Robert T. +9 more
core +1 more source