Results 21 to 30 of about 4,163 (154)
Molecules, 2011 There are more than 100 different ribonucleoside structures incorporated as post-transcriptional modifications, mainly in tRNA and rRNA of both prokaryotes and eukaryotes, and emerging evidence suggests that these modifications function as a system in ...
Peter C. Dedon +8 more
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Biomimetic Ketone Reduction by Disulfide Radical Anion
Molecules, 2021 The conversion of ribonucleosides to 2′-deoxyribonucleosides is catalyzed by ribonucleoside reductase enzymes in nature. One of the key steps in this complex radical mechanism is the reduction of the 3′-ketodeoxynucleotide by a pair of cysteine residues,
Sebastian Barata-Vallejo +5 more
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Ribonucleosides, Aminoacyl- and Peptidyl-RNA: Synthesis, Thermodynamics, and Structure
CHIMIA, 1999 Ribonucleosides, RNA and peptides are prepared to study non-covalent interactions of RNA, aminoacyl- and peptidyl-RNA. Techniques used include chemical synthesis in solution and on solid supports, UV- and NM-detected thermal denaturation, X-ray ...
Ewa Biala +3 more
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Tikrit Journal of Pure Science, 2023 One of the hydrolytic enzymes that catalyzes the hydrolysis of 5' -nucleotides into ribonucleosides and phosphate is the 5'nucleotidase, which is found in several organs.
Sameer M. Al-Gorany +1 more
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Synthesis of New 1,2,3-Triazol-4-yl-quinazoline Nucleoside and Acyclonucleoside Analogues
Molecules, 2014 In this study, we describe the synthesis of 1,4-disustituted-1,2,3-triazolo-quinazoline ribonucleosides or acyclonucleosides by means of 1,3-dipolar cycloaddition between various O or N-alkylated propargyl-quinazoline and 1'-azido-2',3',5'-tri-O ...
Abdelaaziz Ouahrouch +4 more
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MoleculesThe emergence of RNA viruses driven by global population growth and international trade highlights the urgent need for effective antiviral agents that can inhibit viral replication.
Evan Saillard +4 more
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Unnatural Amino Acid and Emerging Chemistry Approaches to Map RNA–Protein Interactions
Angewandte Chemie, Volume 138, Issue 6, 2 February 2026.This review highlights emerging chemistries for mapping RNA–protein interactions, including genetically encoded unnatural amino acids, novel photocrosslinkers, and non‐photoactivatable crosslinking systems. We compare their mechanisms, reactivity and applications, outlining how these next‐generation tools enable higher‐resolution, site‐specific ...
Eryn Lundrigan +3 more
wiley +2 more sources
Deoxyribo‐ and Ribonucleoside H‐Phosphonates [PDF]
Current Protocols in Nucleic Acid Chemistry, 2001 AbstractMost methods for preparing H‐phosphonate monoesters suffer from variable yields and are often incompatible with common protecting groups used in oligonucleotide synthesis. This unit describes four procedures that consistently give high yields of the desired products.
Stawinski, Jacek, Strömberg, Roger
openaire +3 more sources
CHIMIA, 1996 From efforts to improve the biophysical properties of antisense oligonucleotides by incorporating backbone- or sugar-modified nucleoside analogs, 2'-O-methoxyethyl ribonucleosides 8b were identified as building blocks for a second generation of ...
Karl-Heinz Altmann +15 more
doaj +2 more sources
A functional genomics approach to establish the complement of carbohydrate transporters in Streptococcus pneumoniae. [PDF]
PLoS ONE, 2012 The aerotolerant anaerobe Streptococcus pneumoniae is part of the normal nasopharyngeal microbiota of humans and one of the most important invasive pathogens.
Alessandro Bidossi +9 more
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