Results 1 to 10 of about 523,023 (283)

DNA replication stress restricts ribosomal DNA copy number. [PDF]

open access: yesPLoS Genetics, 2017
Ribosomal RNAs (rRNAs) in budding yeast are encoded by ~100-200 repeats of a 9.1kb sequence arranged in tandem on chromosome XII, the ribosomal DNA (rDNA) locus.
Devika Salim   +6 more
doaj   +5 more sources

Ribosomal DNA Copy Number Variation is Coupled with DNA Methylation Changes at the 45S rDNA Locus [PDF]

open access: yesEpigenetics, 2023
The human ribosomal DNA (rDNA) copy number (CN) has been challenging to analyse, and its sequence has been excluded from reference genomes due to its highly repetitive nature. The 45S rDNA locus encodes essential components of the cell, nevertheless rDNA
Aleem Razzaq   +4 more
doaj   +2 more sources

Genome-wide DNA methylation profiles and ribosomal DNA copy number at birth [PDF]

open access: yesEpigenetics
Ribosomal DNA copy number (rDNAcn) and DNA methylation are important modulators of the human genome, both studied in relation to overall cellular function, biological ageing, and disease development.
Kathrin Barth   +5 more
doaj   +2 more sources

CX-5461 Preferentially Induces Top2α-Dependent DNA Breaks at Ribosomal DNA Loci [PDF]

open access: yesBiomedicines
While genotoxic chemotherapeutic agents are among the most effective tools to combat cancer, they are often associated with severe adverse effects caused by indiscriminate DNA damage in non-tumor tissue as well as increased risk of secondary ...
Donald P. Cameron   +8 more
doaj   +2 more sources

RNA polymerase I mutant affects ribosomal RNA processing and ribosomal DNA stability [PDF]

open access: yesRNA Biology
Transcription is a major contributor to genomic instability. The ribosomal RNA (rDNA) gene locus consists of a head-to-tail repeat of the most actively transcribed genes in the genome.
Christophe Normand   +7 more
doaj   +2 more sources

Isolation and study of morphology and phylogeny of arbuscular mycorrhizal fungi coexisting with the roots of some medicinal plants in Kerman province [PDF]

open access: yesمجله بیوتکنولوژی کشاورزی, 2020
Objective Plants that have a symbiotic relationship with arbuscular mycorrhizal fungi (AMF) compared with non-mycorrhizal plants have a higher ability to resist against various biotic and abiotic environmental stresses such as drought, salinity, pests ...
Eidi bazgir   +3 more
doaj   +1 more source

Molecular Identification and Analysis of New Cultivar Wuzhi No. 2 Based on Ribosomal DNA ITS and ITS2 Sequence

open access: yesGuangdong nongye kexue, 2022
【Objective】The study was carried out to explore the molecular identification of Wuzhi No. 2 (original name: Zizhi S2), a new cultivar of Ganoderma sp., by rDNA-ITS sequence analysis and ITS2 secondary structure model.【Method】The sequences of Wuzhi No.
Liyi ZHONG   +3 more
doaj   +1 more source

Characterization of Yeast Ribosomal DNA [PDF]

open access: yesEuropean Journal of Biochemistry, 1975
High‐molecular‐weight yeast ribosomal DNA, purified by preparative Hg2/Cs2SO4 gradient centrifugation, was characterized using RNA‐DNA hybridization, CsCl gradient analysis and denaturation‐renaturation experiments. The following conclusions are drawn from the results of these studies.
J, Retèl, H, Van Keulen
openaire   +2 more sources

Evaluation of the complete nuclear rDNA unit sequence of the jellyfish Cyanea nozakii Kishinouye (Scyphozoa: Semaeostomeae) for molecular discrimination

open access: yesAnimal Cells and Systems, 2021
The harmful jellyfish Cyanea nozakii Kishinouye has frequently occurred on Korean coasts, and its blooms have caused serious ecological and economic damages. DNA sequences of the C. nozakii for molecular detection and discrimination are relatively scarce.
Buhari Lawan Muhammad   +2 more
doaj   +1 more source

Heterogeneity of Pumpkin Ribosomal DNA [PDF]

open access: yesPlant Physiology, 1983
The ribosomal DNA (rDNA) of Cucurbita pepo L. has been found to consist of tandemly arrayed repeat units, most of which are 10 kilobases in length. Thirty-six repeat units, cloned into the HindIII site of pACYC 177, fall into seven classes which differ from each other in length and/or nucleotide sequence.
A, Siegel, K, Kolacz
openaire   +2 more sources

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