Results 1 to 10 of about 287,615 (186)
Ribosomal DNA Copy Number Variation is Coupled with DNA Methylation Changes at the 45S rDNA Locus [PDF]
Epigenetics, 2023 The human ribosomal DNA (rDNA) copy number (CN) has been challenging to analyse, and its sequence has been excluded from reference genomes due to its highly repetitive nature. The 45S rDNA locus encodes essential components of the cell, nevertheless rDNA
Aleem Razzaq +4 more
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RNA polymerase I mutant affects ribosomal RNA processing and ribosomal DNA stability [PDF]
RNA BiologyTranscription is a major contributor to genomic instability. The ribosomal RNA (rDNA) gene locus consists of a head-to-tail repeat of the most actively transcribed genes in the genome.
Christophe Normand +7 more
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CX-5461 Preferentially Induces Top2α-Dependent DNA Breaks at Ribosomal DNA Loci [PDF]
BiomedicinesWhile genotoxic chemotherapeutic agents are among the most effective tools to combat cancer, they are often associated with severe adverse effects caused by indiscriminate DNA damage in non-tumor tissue as well as increased risk of secondary ...
Donald P. Cameron +8 more
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DNA Methylation Analysis of Ribosomal DNA in Adults With Down Syndrome [PDF]
Frontiers in Genetics, 2022 Control of ribosome biogenesis is a critical aspect of the regulation of cell metabolism. As ribosomal genes (rDNA) are organized in repeated clusters on chromosomes 13, 14, 15, 21, and 22, trisomy of chromosome 21 confers an excess of rDNA copies to ...
Francesco Ravaioli +26 more
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Isolation and study of morphology and phylogeny of arbuscular mycorrhizal fungi coexisting with the roots of some medicinal plants in Kerman province [PDF]
مجله بیوتکنولوژی کشاورزی, 2020 Objective Plants that have a symbiotic relationship with arbuscular mycorrhizal fungi (AMF) compared with non-mycorrhizal plants have a higher ability to resist against various biotic and abiotic environmental stresses such as drought, salinity, pests ...
Eidi bazgir +3 more
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DNA replication stress restricts ribosomal DNA copy number. [PDF]
PLoS Genetics, 2017 Ribosomal RNAs (rRNAs) in budding yeast are encoded by ~100-200 repeats of a 9.1kb sequence arranged in tandem on chromosome XII, the ribosomal DNA (rDNA) locus.
Devika Salim +6 more
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Animal Cells and Systems, 2021 The harmful jellyfish Cyanea nozakii Kishinouye has frequently occurred on Korean coasts, and its blooms have caused serious ecological and economic damages. DNA sequences of the C. nozakii for molecular detection and discrimination are relatively scarce.
Buhari Lawan Muhammad +2 more
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Guangdong nongye kexue, 2022 【Objective】The study was carried out to explore the molecular identification of Wuzhi No. 2 (original name: Zizhi S2), a new cultivar of Ganoderma sp., by rDNA-ITS sequence analysis and ITS2 secondary structure model.【Method】The sequences of Wuzhi No.
Liyi ZHONG +3 more
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Organization of the bacterial nucleoid by DNA-bridging proteins and globular crowders [PDF]
Frontiers in Microbiology, 2023, 14, 2023 The genomic DNA of bacteria occupies only a fraction of the cell called the nucleoid, although it is not bounded by any membrane and would occupy a volume hundreds of times larger than the cell in the absence of constraints. The two most important contributions to the compaction of the DNA coil are the cross-linking of the DNA by nucleoid proteins ...
arxiv +1 more source
Dynamics of ribosomes in mRNA translation under steady and non-steady state conditions [PDF]
Phys. Rev. E 101, 062404 (2020), 2020 Recent advances in DNA sequencing and fluorescence imaging have made it possible to monitor the dynamics of ribosomes actively engaged in messenger RNA (mRNA) translation. Here, we model these experiments within the inhomogeneous totally asymmetric simple exclusion process (TASEP) using realistic kinetic parameters.
arxiv +1 more source