Results 1 to 10 of about 534,315 (335)

DNA replication stress restricts ribosomal DNA copy number. [PDF]

PLoS Genetics, 2017
Ribosomal RNAs (rRNAs) in budding yeast are encoded by ~100-200 repeats of a 9.1kb sequence arranged in tandem on chromosome XII, the ribosomal DNA (rDNA) locus.
Devika Salim, William D Bradford, Amy Freeland, Gillian Cady, Jianmin Wang, Steven C Pruitt, Jennifer L Gerton   +6 more
doaj   +5 more sources

Ribosomal DNA Copy Number Variation is Coupled with DNA Methylation Changes at the 45S rDNA Locus [PDF]

Epigenetics, 2023
The human ribosomal DNA (rDNA) copy number (CN) has been challenging to analyse, and its sequence has been excluded from reference genomes due to its highly repetitive nature. The 45S rDNA locus encodes essential components of the cell, nevertheless rDNA
Aleem Razzaq, Yosra Bejaoui, Tanvir Alam, Mohamad Saad, Nady El Hajj   +4 more
doaj   +2 more sources

RNA polymerase I mutant affects ribosomal RNA processing and ribosomal DNA stability [PDF]

RNA Biology
Transcription is a major contributor to genomic instability. The ribosomal RNA (rDNA) gene locus consists of a head-to-tail repeat of the most actively transcribed genes in the genome.
Christophe Normand, Christophe Dez, Lise Dauban, Sophie Queille, Sarah Danché, Sarra Abderrahmane, Frederic Beckouet, Olivier Gadal   +7 more
doaj   +2 more sources

CX-5461 Preferentially Induces Top2α-Dependent DNA Breaks at Ribosomal DNA Loci [PDF]

Biomedicines
While genotoxic chemotherapeutic agents are among the most effective tools to combat cancer, they are often associated with severe adverse effects caused by indiscriminate DNA damage in non-tumor tissue as well as increased risk of secondary ...
Donald P. Cameron, Jirawas Sornkom, Sameerh Alsahafi, Denis Drygin, Gretchen Poortinga, Grant A. McArthur, Nadine Hein, Ross Hannan, Konstantin I. Panov   +8 more
doaj   +2 more sources

Variant ribosomal DNA is essential for female differentiation in zebrafish. [PDF]

Philos Trans R Soc Lond B Biol Sci
Moser TV, Bond DM, Hore TA.
europepmc   +2 more sources

Chromosome-specific epigenetic control and transmission of ribosomal DNA arrays in Hominidae genomes. [PDF]

Cell Genom
Potapova TA, Kostos P, McKinney S, Borchers M, Haug J, Guarracino A, Solar SJ, Mattingly M, Anez GM, de Lima LG, Wang Y, Zhao C, Hall K, Gogol M, Hoffman S, Antipov D, Rhie A, Cechova M, Miga KH, Garrison E, Phillippy AM, Gerton JL.   +21 more
europepmc   +3 more sources

Molecular Identification and Analysis of New Cultivar Wuzhi No. 2 Based on Ribosomal DNA ITS and ITS2 Sequence

Guangdong nongye kexue, 2022
【Objective】The study was carried out to explore the molecular identification of Wuzhi No. 2 (original name: Zizhi S2), a new cultivar of Ganoderma sp., by rDNA-ITS sequence analysis and ITS2 secondary structure model.【Method】The sequences of Wuzhi No.
Liyi ZHONG, Zhenghe YING, Xinrui LIU, Tiqiang CHEN   +3 more
doaj   +1 more source

Isolation and study of morphology and phylogeny of arbuscular mycorrhizal fungi coexisting with the roots of some medicinal plants in Kerman province [PDF]

مجله بیوتکنولوژی کشاورزی, 2020
Objective Plants that have a symbiotic relationship with arbuscular mycorrhizal fungi (AMF) compared with non-mycorrhizal plants have a higher ability to resist against various biotic and abiotic environmental stresses such as drought, salinity, pests ...
Eidi bazgir, Narges Hatami, Ebrahim Sedaghati, Mostafa Darvishnia   +3 more
doaj   +1 more source

Evaluation of the complete nuclear rDNA unit sequence of the jellyfish Cyanea nozakii Kishinouye (Scyphozoa: Semaeostomeae) for molecular discrimination

Animal Cells and Systems, 2021
The harmful jellyfish Cyanea nozakii Kishinouye has frequently occurred on Korean coasts, and its blooms have caused serious ecological and economic damages. DNA sequences of the C. nozakii for molecular detection and discrimination are relatively scarce.
Buhari Lawan Muhammad, Yoseph Seo, Jang-Seu Ki   +2 more
doaj   +1 more source

Challenges and Approaches to Genotyping Repetitive DNA

G3: Genes, Genomes, Genetics, 2020
Individuals within a species can exhibit vast variation in copy number of repetitive DNA elements. This variation may contribute to complex traits such as lifespan and disease, yet it is only infrequently considered in genotype-phenotype associations ...
Elizabeth A. Morton, Ashley N. Hall, Elizabeth Kwan, Calvin Mok, Konstantin Queitsch, Vivek Nandakumar, John Stamatoyannopoulos, Bonita J. Brewer, Robert Waterston, Christine Queitsch   +9 more
doaj   +1 more source