Results 81 to 90 of about 1,591,440 (405)
Possible role of human ribonuclease dicer in the regulation of R loops
FEBS Open Bio, EarlyView.R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik +2 more
wiley +1 more source
Methylation of Ribosomal RNA: A Mitochondrial Perspective
Frontiers in Genetics, 2020 Ribosomal RNA (rRNA) from all organisms undergoes post-transcriptional modifications that increase the diversity of its composition and activity. In mitochondria, specialized mitochondrial ribosomes (mitoribosomes) are responsible for the synthesis of 13
M. Isabel G. Lopez Sanchez +9 more
doaj +1 more source
RNA G-quadruplex structures control ribosomal protein production
Scientific Reports, 2021 Four-stranded G-quadruplex (G4) structures form from guanine-rich tracts, but the extent of their formation in cellular RNA and details of their role in RNA biology remain poorly defined.
Dhaval Varshney +5 more
doaj +1 more source
The ribosomal protein RACK1 is required for microRNA function in both C. elegans and humans [PDF]
, 2011 Despite the importance of microRNAs (miRNAs) in gene regulation, it is unclear how the miRNA-Argonaute complex-or miRNA-induced silencing complex (miRISC)-can regulate the translation of their targets in such diverse ways.
Bajan, Sarah +7 more
core +2 more sources
FEBS Open Bio, EarlyView.Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran +3 more
wiley +1 more source
Ribosomal transcription is regulated by PGC-1alpha and disturbed in Huntington’s disease
Scientific Reports, 2017 PGC-1α is a versatile inducer of mitochondrial biogenesis and responsive to the changing energy demands of the cell. As mitochondrial ATP production requires proteins that derive from translation products of cytosolic ribosomes, we asked whether PGC-1α ...
Sarah Jesse +14 more
doaj +1 more source
16S ribosomal RNA gene-based metagenomics: A review
Biomedical Research Journal, 2020 With the advent of contemporary molecular tools, the conventional microbiological isolation, enrichment techniques, and approaches have changed considerably.
Asmita Kamble +2 more
doaj +1 more source
Ribosomal RNA regulates chromosome clustering during mitosis
Cell Discovery, 2022 Noncoding RNAs are known to associate with mitotic chromosomes, but the identities and functions of chromosome-associated RNAs in mitosis remain elusive. Here, we show that rRNA species associate with condensed chromosomes during mitosis.
Kai Ma +7 more
doaj +1 more source
Magnification of Genes Coding for Ribosomal RNA in Saccharomyces cerevisiae [PDF]
, 1977 When a strain of Saccharomyces cerevisiae monosomic for chromosome I and initially deficient for 25% of the genes coding for ribosomal RNA is repeatedly subcultured, the number of these genes increases to and remains stable at the number in the wild type.
Halvorson, Harlyn O., Kaback, David B.
core
Multiple prebiotic metals mediate translation. [PDF]
, 2018 Today, Mg2+ is an essential cofactor with diverse structural and functional roles in life's oldest macromolecular machine, the translation system. We tested whether ancient Earth conditions (low O2, high Fe2+, and high Mn2+) can revert the ribosome to a ...
Bowman, Jessica C +8 more
core +1 more source