Results 81 to 90 of about 1,934 (175)

Ribosome-Inactivating Proteins: From Plant Defense to Tumor Attack

open access: yesToxins, 2010
Ribosome-inactivating proteins (RIPs) are EC3.2.32.22 N-glycosidases that recognize a universally conserved stem-loop structure in 23S/25S/28S rRNA, depurinating a single adenine (A4324 in rat) and irreversibly blocking protein translation, leading ...
Maria Serena Fabbrini   +3 more
doaj   +1 more source

Interaction between maize ribosome-inactivating protein and ribosomes [PDF]

open access: yes, 2011
Poster Presentation: abstract no. A11Ribosome‐inactivating proteins (RIPs) represent a group of N‐glycosidases which can cleave the N‐glycosidic bond of adenine at 23S and 28S ribosomal RNA (rRNA) of ribosome and subsequently lead to a halt of protein ...
Au, SWM   +6 more
core  

Food prospects and nutraceutical attributes of Momordica species: A potential tropical bioresources – A review [PDF]

open access: yes, 1937
Plants with potential therapeutic values have been used from time immemorial to cure various ailments and infectious diseases. Of late, scientific evidences have been provided on the potential therapeutic agent exhibited by certain traditionally used ...
Nagarani, Gunasekaran   +2 more
core   +1 more source

Cloning and Bacterial Expression of Karasurins, Ribosome-Inactivating Proteins (RIPs) from Trichosanthes Kirilowii var. Japonica

open access: yesPlant Biotechnology, 2001
A genomic clone encoding a karasurin precursor was isolated from root tubers of Trichosanthes kirilowii var. japonica. The sequence analysis indicates that karasurin-A and karasurin-C exhibiting abortifacient and ribosome-inhibiting activities are produced from a common karasurin precursor by proteolitically cleaving at a different site.
Hajime MIZUKAMI   +4 more
openaire   +2 more sources

Site‐Specific Mitochondrial RNA N1‐Methyladenosine Demethylation via an Engineered MTS‐PUF‐ALKBH3 Fusion Protein

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
A CRISPR‐free mitochondrial RNA m1A demethylation (MRD) editor combining MTS, PUF proteins, and ALKBH3 enables precise m1A removal from mitochondrial mRNA and tRNA, which influences mitochondrial protein levels, cellular proliferation, ATP production, and mitochondrial respiration. Subsequently, in vivo demethylation of the m1A modification is achieved
Xiangrui Li   +13 more
wiley   +1 more source

Unexpected Toxicity of Green Tea Polyphenols in Combination with the Sambucus RIL Ebulin

open access: yesToxins, 2020
The safety of concentrated food complements intake is a major health concern. It has been well established that green tea polyphenols (GTPs) consumption promotes healthy effects.
M. Ángeles Rojo   +6 more
doaj   +1 more source

Aktivitas Kitinase dan Peroksidase dari Ekstrak Kasar Protein Asal Kalus dan Berbagai Jaringan Tanaman Trichosanthes Cucumerina Var. Anguina [PDF]

open access: yes, 2012
Chitinase and peroxydase are important bioactive proteins or are specific enzymes that are related to plant resistance to pathogens. The aims of the research were to analyze the chitinase and peroxidase activities of crude protein extract from calli ...
Artika, I. M. (I)   +5 more
core  

Reporter Assay for Endo/Lysosomal Escape of Toxin-Based Therapeutics [PDF]

open access: yes, 2014
Protein-based therapeutics with cytosolic targets are capable of exhibiting their therapeutic effect once they have escaped from the endosomes or lysosomes.
Bhargava, Cheenu   +8 more
core   +2 more sources

Erythropoiesis in health and disease: Distinguishing defective and ineffective erythropoiesis

open access: yesHemaSphere, Volume 10, Issue 1, January 2026.
Abstract Erythropoiesis is a finely regulated process ensuring continuous red blood cell production to maintain oxygen delivery. Disruptions in this process give rise to defective erythropoiesis, characterized by impaired lineage commitment and progenitor development, and ineffective erythropoiesis (IE), marked by expansion of erythroid progenitors ...
Sara El Hoss   +3 more
wiley   +1 more source

DIANTHIN, a negative selection marker in tobacco, is non-toxic in transgenic rice and confers sheath blight resistance

open access: yesBiologia Plantarum, 2010
The DIANTHIN gene encoding a ribosome-inactivating protein (RIP) from Dianthus caryophyllus L. was tested for negative selection in tobacco and rice. Tobacco leaf discs and scutellum-derived callus of rice were transformed with Agrobacterium tumefaciens ...
J. M. Shah, K. Veluthambi
doaj   +1 more source

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