Results 41 to 50 of about 254,623 (219)

The coordinated management of ribosome and translation during injury and regeneration

open access: yesFrontiers in Cell and Developmental Biology, 2023
Diverse acute and chronic injuries induce damage responses in the gastrointestinal (GI) system, and numerous cell types in the gastrointestinal tract demonstrate remarkable resilience, adaptability, and regenerative capacity in response to stress ...
Thanh Nguyen   +4 more
doaj   +1 more source

The inhibition of ribosomal ribonuclease by bacterial ribosomes [PDF]

open access: yesBiochemical Journal, 1965
1. A comparison has been made between the ribonuclease activities of untreated ribosomes from Escherichia coli B and Pseudomonas fluorescens and the activities of ribosomes on to which ribosomal ribonuclease from E. coli B has been adsorbed. 2. The normal ribosomes from both species were stable in 5-10mm-Mg(2+) (I0.16) at pH6. The RNA in ribosomes from
HE Wade, HK Robinson
openaire   +3 more sources

Hepatitis C virus 3'UTR regulates viral translation through direct interactions with the host translation machinery. [PDF]

open access: yes, 2013
The 3' untranslated region (3'UTR) of hepatitis C virus (HCV) messenger RNA stimulates viral translation by an undetermined mechanism. We identified a high affinity interaction, conserved among different HCV genotypes, between the HCV 3'UTR and the host ...
Bai, Yun   +2 more
core   +2 more sources

Upregulated ribosome pathway plays a key role in HDAC4, improving the survival rate and biofunction of chondrocytes

open access: yesBone & Joint Research, 2023
Aims: To explore the novel molecular mechanisms of histone deacetylase 4 (HDAC4) in chondrocytes via RNA sequencing (RNA-seq) analysis. Methods: Empty adenovirus (EP) and a HDAC4 overexpression adenovirus were transfected into cultured human chondrocytes.
Li Guo   +9 more
doaj   +1 more source

sORFs.org : a repository of small ORFs identified by ribosome profiling [PDF]

open access: yes, 2015
With the advent of ribosome profiling, a next generation sequencing technique providing a ‘snap-shot’ of translated mRNA in a cell, many short open reading frames (sORFs) with were identified.
Crappé, Jeroen   +5 more
core   +3 more sources

Physiological importance and role of Mg2+ in improving bacterial resistance to cesium

open access: yesFrontiers in Microbiology, 2023
Cesium (Cs) is an alkali metal with radioactive isotopes such as 137Cs and 134Cs. 137Cs, a product of uranium fission, has garnered attention as a radioactive contaminant.
Yoshiki Ishida   +6 more
doaj   +1 more source

The Reverse Side of a Coin: “Factor-Free” Ribosomal Protein Synthesis In Vitro is a Consequence of the In Vivo Proofreading Mechanism

open access: yesBiomolecules, 2019
This paper elucidates a close connection between two well-known facts that until now have seemed independent: (i) the quality control (“proofreading”) of the emerging amino acid sequence, occurring during the normal, elongation-factor ...
Alexei V. Finkelstein
doaj   +1 more source

40S ribosome biogenesis co-factors are essential for gametophyte and embryo development [PDF]

open access: yes, 2013
Ribosome biogenesis is well described in Saccharomyces cerevisiae. In contrast only very little information is available on this pathway in plants. This study presents the characterization of five putative protein co-factors of ribosome biogenesis in ...
Bohnsack, Markus T.   +6 more
core   +2 more sources

Molecular Dynamics Simulations Suggest a Non-Doublet Decoding Model of −1 Frameshifting by tRNASer3

open access: yesBiomolecules, 2019
In-frame decoding in the ribosome occurs through canonical or wobble Watson−Crick pairing of three mRNA codon bases (a triplet) with a triplet of anticodon bases in tRNA.
Thomas Caulfield   +3 more
doaj   +1 more source

Growth-laws and invariants from ribosome biogenesis in lower Eukarya [PDF]

open access: yesPhys. Rev. Research 3, 013020 (2021), 2020
Eukarya and Bacteria are the most evolutionarily distant domains of life, which is reflected by differences in their cellular structure and physiology. For example, Eukarya feature membrane-bound organelles such as nuclei and mitochondria, whereas Bacteria have none.
arxiv   +1 more source

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