Results 51 to 60 of about 358,575 (311)

sORFs.org : a repository of small ORFs identified by ribosome profiling [PDF]

open access: yes, 2015
With the advent of ribosome profiling, a next generation sequencing technique providing a ‘snap-shot’ of translated mRNA in a cell, many short open reading frames (sORFs) with were identified.
Crappé, Jeroen   +5 more
core   +3 more sources

Physiological importance and role of Mg2+ in improving bacterial resistance to cesium

open access: yesFrontiers in Microbiology, 2023
Cesium (Cs) is an alkali metal with radioactive isotopes such as 137Cs and 134Cs. 137Cs, a product of uranium fission, has garnered attention as a radioactive contaminant.
Yoshiki Ishida   +6 more
doaj   +1 more source

Growth-laws and invariants from ribosome biogenesis in lower Eukarya [PDF]

open access: yesPhys. Rev. Research 3, 013020 (2021), 2020
Eukarya and Bacteria are the most evolutionarily distant domains of life, which is reflected by differences in their cellular structure and physiology. For example, Eukarya feature membrane-bound organelles such as nuclei and mitochondria, whereas Bacteria have none.
arxiv   +1 more source

The Reverse Side of a Coin: “Factor-Free” Ribosomal Protein Synthesis In Vitro is a Consequence of the In Vivo Proofreading Mechanism

open access: yesBiomolecules, 2019
This paper elucidates a close connection between two well-known facts that until now have seemed independent: (i) the quality control (“proofreading”) of the emerging amino acid sequence, occurring during the normal, elongation-factor ...
Alexei V. Finkelstein
doaj   +1 more source

Ribosome collisions trigger cis-acting feedback inhibition of translation initiation

open access: yeseLife, 2020
Translation of aberrant mRNAs can cause ribosomes to stall, leading to collisions with trailing ribosomes. Collided ribosomes are specifically recognised by ZNF598 to initiate protein and mRNA quality control pathways.
S. Juszkiewicz   +5 more
semanticscholar   +1 more source

40S ribosome biogenesis co-factors are essential for gametophyte and embryo development [PDF]

open access: yes, 2013
Ribosome biogenesis is well described in Saccharomyces cerevisiae. In contrast only very little information is available on this pathway in plants. This study presents the characterization of five putative protein co-factors of ribosome biogenesis in ...
Bohnsack, Markus T.   +6 more
core   +2 more sources

Active role of elongation factor G in maintaining the mRNA reading frame during translation. [PDF]

open access: yes, 2019
During translation, the ribosome moves along the mRNA one codon at a time with the help of elongation factor G (EF-G). Spontaneous changes in the translational reading frame are extremely rare, yet how the precise triplet-wise step is maintained is not ...
Belardinelli, R.   +5 more
core   +2 more sources

Molecular Dynamics Simulations Suggest a Non-Doublet Decoding Model of −1 Frameshifting by tRNASer3

open access: yesBiomolecules, 2019
In-frame decoding in the ribosome occurs through canonical or wobble Watson−Crick pairing of three mRNA codon bases (a triplet) with a triplet of anticodon bases in tRNA.
Thomas Caulfield   +3 more
doaj   +1 more source

Modelling the effect of ribosome mobility on the rate of protein synthesis [PDF]

open access: yesEur. Phys. J. E 44, 19 (2021), 2020
Translation is one of the main steps in the synthesis of proteins. It consists of ribosomes that translate sequences of nucleotides encoded on mRNA into polypeptide sequences of amino acids. Ribosomes bound to mRNA move unidirectionally, while unbound ribosomes diffuse in the cytoplasm.
arxiv   +1 more source

Application of fluorescence correlation spectroscopy to investigate the dynamics of a ribosome-associated trigger factor in Escherichia coli

open access: yesFrontiers in Molecular Biosciences, 2022
Co-translational protein folding is one of the central topics in molecular biology. In Escherichia coli, trigger factor (TF) is a primary chaperone that facilitates co-translational folding by directly interacting with nascent polypeptide chains on ...
Tatsuya Niwa   +7 more
doaj   +1 more source

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