Results 11 to 20 of about 30,415 (253)

Antiviral Activity of PD-L1 and PD-L4, Type 1 Ribosome Inactivating Proteins from Leaves of Phytolacca dioica L. in the Pathosystem Phaseolus vulgaris–Tobacco Necrosis Virus (TNV)

Toxins, 2020
Using the pathosystem Phaseolus vulgaris–tobacco necrosis virus (TNV), we demonstrated that PD-L1 and PD-L4, type-1 ribosome inactivating proteins (RIPs) from leaves of Phytolacca dioica L., possess a strong antiviral activity.
Daniela Bulgari, Nicola Landi, Sara Ragucci, Franco Faoro, Antimo Di Maro   +4 more
doaj   +2 more sources

Type 1 ribosome-inactivating proteins depurinate plant 25S rRNA without species specificity

Nucleic Acids Research, 1992
Four different type 1 ribosome-inactivating proteins (RIPs) with RNA N-glycosidase activity were tested for their ability to attack the large rRNA of plant ribosomes derived from tobacco plants, as well as from the plant species from which the particular RIP had been isolated.
J, Prestle, M, Schönfelder, G, Adam, K W, Mundry   +3 more
openaire   +4 more sources

Hortensins, Type 1 Ribosome-Inactivating Proteins from Seeds of Red Mountain Spinach: Isolation, Characterization, and Their Effect on Glioblastoma Cells

Toxins
Ribosome inactivating proteins (RIPs) are specific N-β-glycosylases that are well-characterized in plants. Their enzymatic action is to damage ribosomes, thereby blocking protein translation.
Sara Ragucci, Veronica Russo, Angela Clemente, Maria Giuseppina Campanile, Maria Antonietta Oliva, Nicola Landi, Paolo Vincenzo Pedone, Antonietta Arcella, Antimo Di Maro   +8 more
doaj   +2 more sources

Quinoa as source of type 1 ribosome inactivating proteins: A novel knowledge for a revision of its consumption

Food Chemistry, 2021
This study investigates on the presence of toxic proteins in quinoa seeds. To this aim, a plethora of biochemical approaches were adopted for the purification and characterization of quinoin, a type 1 ribosome-inactivating protein (RIP) contained in quinoa seeds.
Landi, Nicola, Ruocco, Maria Rosaria, Ragucci, Sara, Aliotta, Federica, Nasso, Rosarita, Pedone, Paolo V, Di Maro, Antimo   +6 more
openaire   +6 more sources

Kirkiin: A New Toxic Type 2 Ribosome-Inactivating Protein from the Caudex of Adenia kirkii

Toxins, 2021
Ribosome-inactivating proteins (RIPs) are plant toxins that irreversibly damage ribosomes and other substrates, thus causing cell death. RIPs are classified in type 1 RIPs, single-chain enzymatic proteins, and type 2 RIPs, consisting of active A chains ...
Massimo Bortolotti, Stefania Maiello, José M. Ferreras, Rosario Iglesias, Letizia Polito, Andrea Bolognesi   +5 more
doaj   +2 more sources

Sensitivity of Translation byBrevibacterium lactofermentumRibosomes to Type 1 and Type 2 Ribosome-inactivating Proteins [PDF]

Bioscience, Biotechnology, and Biochemistry, 1994
An active cell-free translation system was prepared from Brevibacterium lactofermentum, a Gram-positive bacteria used in molecular cloning and protein expression. The system contained high speed postribosomal supernatant (S 370), purified ribosomes and a tRNA mixture from Escherichia coli, and synthesized polyuridylic acid-directed polyphenylalanine ...
J M, Ferreras, C, Alegre, R, Iglesias, T, Girbes   +3 more
openaire   +3 more sources

Ribosome Inactivating Proteins from Rosaceae

Molecules, 2016
Ribosome-inactivating proteins (RIPs) are widespread among higher plants of different taxonomic orders. In this study, we report on the RIP sequences found in the genome/transcriptome of several important Rosaceae species, including many economically ...
Chenjing Shang, Pierre Rougé, Els J. M. Van Damme   +2 more
doaj   +2 more sources

Constitutive and inducible type 1 ribosome‐inactivating proteins (RIPs) in elderberry (Sambucus nigra L.)

FEBS Letters, 1998
Two novel highly basic type 1 (single chain) ribosome‐inactivating proteins (RIPs) with N‐glycosidase activity have been found in elderberries (the fruits of Sambucus nigra L.). Mass spectrometry of these RIPs, which we named nigritins f1 and f2, gave M r values of 24 095 and 23 565, respectively.
de Benito, Fernando M, Iglesias, Rosario, Ferreras, José Miguel, Citores, Lucı́a, Camafeita, Emilio, Méndez, Enrique, Girbés, Tomás   +6 more
openaire   +3 more sources

Ebulitins: A new family of type 1 ribosome‐inactivating proteins (rRNA N‐glycosidases) from leaves of Sambucus ebulus L. that coexist with the type 2 ribosome‐inactivating protein ebulin 1

FEBS Letters, 1995
A new family of single chain (type 1) ribosome‐inactivating proteins (RIPs), that we have named ebulitins, have been found in mature leaves of Sambucus ebulus L., a caprifoliaceae plant also known to contain a non‐toxic two chain (type 2) RIP named ebulin 1 in its leaves.
de Benito, Fernando M., Citores, Lucía, Iglesias, Rosario, Miguel Ferreras, J., Soriano, Fernando, Arias, Javier, Méndez, Enrique, Girbés, Tomás   +7 more
openaire   +3 more sources

Ribosome-Inactivating and Related Proteins

Toxins, 2015
Ribosome-inactivating proteins (RIPs) are toxins that act as N-glycosidases (EC 3.2.2.22). They are mainly produced by plants and classified as type 1 RIPs and type 2 RIPs.
Joachim Schrot, Alexander Weng, Matthias F. Melzig   +2 more
doaj   +2 more sources