Results 11 to 20 of about 31,654 (255)
Food Chemistry, 2020 This study investigates on the presence of toxic proteins in quinoa seeds. To this aim, a plethora of biochemical approaches were adopted for the purification and characterization of quinoin, a type 1 ribosome-inactivating protein (RIP) contained in ...
N. Landi +6 more
semanticscholar +6 more sources
Biocontrol Potential of Sodin 5, Type 1 Ribosome-Inactivating Protein from Salsola soda L. Seeds
BiomoleculesSodin 5 is a type 1 ribosome-inactivating protein isolated from the seeds of Salsola soda L., an edible halophytic plant that is widespread in southern Europe, close to the coast.
Monika Novak Babič +8 more
doaj +4 more sources
Elderberries: A Source of Ribosome-Inactivating Proteins with Lectin Activity
Molecules, 2015 Sambucus (Adoxaceae) species have been used for both food and medicine purposes. Among these, Sambucus nigra L. (black elder), Sambucus ebulus L. (dwarf elder), and Sambucus sieboldiana L. are the most relevant species studied.
Jesús Tejero +7 more
doaj +2 more sources
Frontiers in Bioscience-LandmarkBackground: Ribosome inactivating proteins (RIPs) are N-glycosylases found in various plants that are able to specifically and irreversibly inhibit protein translation, thereby leading to cell death. Their cytotoxic properties have attracted attention in
Filomena Mottola +6 more
doaj +2 more sources
Iris bulbs express type 1 and type 2 ribosome-inactivating proteins with unusual properties. [PDF]
Plant Physiology, 2001 Abstract Two closely related lectins from bulbs of the Dutch iris (Iris hollandica var. Professor Blaauw) have been isolated and cloned. Both lectins, called Iris agglutinin b and Iris agglutinin r, possess N-glycosidase activity and share a high sequence similarity with previously described type 2 ribosome-inactivating proteins (RIP ...
Qiang Hao +6 more
semanticscholar +3 more sources
Type 1 ribosome-inactivating proteins depurinate plant 25S rRNA without species specificity.
Nucleic Acids Research, 1992 Four different type 1 ribosome-inactivating proteins (RIPs) with RNA N-glycosidase activity were tested for their ability to attack the large rRNA of plant ribosomes derived from tobacco plants, as well as from the plant species from which the particular RIP had been isolated.
J. Prestle +3 more
semanticscholar +4 more sources
Comparison of the embryotoxic effects of saporin, agrostin (type 1 ribosome-inactivating proteins) and ricin (a type 2 ribosome-inactivating protein). [PDF]
Pharmacology and Toxicology, 2001 Abstract: The effects of two type I ribosome‐inactivating proteins, saporin and agrostin, and the type 2 ribosome‐inactivating protein ricin and its constituent A and B chains, on the development of cultured mouse embryos, were investigated. Saporin and agrostin had similar embryotoxicity which was approximately 105 times weaker than that of ricin and ...
W. Chan, T. Ng
semanticscholar +3 more sources
FEBS Letters, 1998 Two novel highly basic type 1 (single chain) ribosome‐inactivating proteins (RIPs) with N‐glycosidase activity have been found in elderberries (the fruits of Sambucus nigra L.). Mass spectrometry of these RIPs, which we named nigritins f1 and f2, gave M r values of 24 095 and 23 565, respectively.
F. de Benito +6 more
semanticscholar +3 more sources
Charged and hydrophobic surfaces on the a chain of shiga-like toxin 1 recognize the C-terminal domain of ribosomal stalk proteins. [PDF]
PLoS ONE, 2012 Shiga-like toxins are ribosome-inactivating proteins (RIP) produced by pathogenic E. coli strains that are responsible for hemorrhagic colitis and hemolytic uremic syndrome.
Andrew J McCluskey +5 more
doaj +1 more source
Molecular action of the type 1 ribosome‐inactivating protein saporin 5 on Vicia sativa ribosomes [PDF]
FEBS Letters, 1993 The type 1 ribosome‐inactivating protein (RIP) saporin 5 isolated from seeds of Saponaria officinalis L. strongly inhibited translation carried out by Vicia sativa L. purified ribosomes. The toxin multidepurinated V. sativa rRNA, which upon treatment with acid aniline releases several RNA fragments including an RNA fragment of approximately 370 ...
Iglesias, Rosario +5 more
openaire +3 more sources