Results 161 to 170 of about 23,875 (181)

Ribosome-Inactivating Proteins in Cereals

2010
Plants constitutively accumulate proteins that are either toxic or inhibitory against pathogens, including ribosome-inactivating proteins (RIPs) and N-glycosidases that depurinate the universally conserved α-sarcin loop of large rRNAs. Cereal RIPs share a high similarity with all the other RIPs; however, they retain characteristic features forming a ...
Carlotta Balconi, Chiara Lanzanova, Mario Motto   +2 more
openaire   +1 more source

Occupational sensitization to ribosome‐inactivating proteins in researchers

Clinical & Experimental Allergy, 2005
SummaryBackground Ribosome‐inactivating proteins (RIPs) are expressed in many plants. Because of their anti‐infectious and anti‐proliferative effects, intensive research is going on for applying these toxins in therapy against viral infections or malignancies.
K, Szalai, I, Schöll, E, Förster-Waldl, L, Polito, A, Bolognesi, E, Untersmayr, A B, Riemer, G, Boltz-Nitulescu, F, Stirpe, E, Jensen-Jarolim   +9 more
openaire   +3 more sources

Isolation and Purification of Ribosome-Inactivating Proteins

2005
Ribosome-inactivating proteins (RIPs) are cytotoxic N-glycosidases identified in plants, fungi, and bacteria. RIPs inhibit protein synthesis by virtue of their enzymatic activity, selectively cleaving a specific adenine residue from a highly conserved, surface-exposed, stem-loop (S/R loop) structure in the 28S rRNA of ribosomes.
Sang-Wook, Park, Balakrishnan, Prithiviraj, Ramarao, Vepachedu, Jorge M, Vivanco   +3 more
openaire   +2 more sources

Ribosome inactivating proteins of plants.

Seminars in cell biology, 1992
Many plant tissues produce single chain proteins which can enzymatically remove a specific adenine residue from ribosomal RNA. Although these proteins are potently toxic to isolated ribosomes, they are non-toxic to intact cells, being unable to gain access to their ribosomal substrate.
J M, Lord, M R, Hartley, L M, Roberts
openaire   +1 more source

Immunotoxins containing single chain ribosome-inactivating proteins

1988
We have summarized what is currently known about the distribution, biological role, and the mechanism of action of the single chain ribosome-inactivating proteins and described the purification of one of them, gelonin, as an example. ITs have been made with several of these proteins and, depending upon the antibody used for conjugation, these ...
J M, Lambert, W A, Blättler, G D, McIntyre, V S, Goldmacher, C F, Scott   +4 more
openaire   +2 more sources

Virus resistance mediated by ribosome inactivating proteins

2000
Publisher Summary This chapter describes recent advances in understanding the structure and function of ribosome inactivating proteins (RIPs) and the mechanism of their antiviral activity. RIPs are widely distributed among plants, fungi, and bacteria.
P, Wang, N E, Tumer
openaire   +2 more sources

Ribosome-inactivating proteins: From toxins to useful proteins

Toxicon, 2013
Ribosome-inactivating proteins (RIPs) either single-chain (type 1) or two-chain (type 2) are frequent in plants, often in multiple forms. They are RNA N-glycosidases, have antiviral, antifungal and insecticidal activity. Their expression in plants is increased under stressful conditions.
openaire   +2 more sources

Ribosome‐inactivating Proteins

2014
Hendrik Fuchs, Stefan Barth
openaire   +2 more sources

Ribosome-inactivating proteins from plants

Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, 1993
L, Barbieri, M G, Battelli, F, Stirpe
openaire   +2 more sources

Biotechnology of ribosome-inactivating proteins

1993
See the proper ...
SANITA' di TOPPI, LUIGI, SPANO' L.
openaire   +1 more source