TRAIL (CD253) Sensitizes Human Airway Epithelial Cells to Toxin-Induced Cell Death
mSphere, 2018 Inhalation of ricin toxin is associated with the onset of acute respiratory distress syndrome (ARDS), characterized by hemorrhage, inflammatory exudates, and tissue edema, as well as the nearly complete destruction of the lung epithelium.
Yinghui Rong +4 more
doaj +1 more source
The role of CDC48 in the retro-translocation of non-ubiquitinated toxin substrates in plant cells [PDF]
, 2009 When the catalytic A subunits of the castor bean toxins ricin and Ricinus communis agglutinin (denoted as RTA and RCA A, respectively) are delivered into the endoplasmic reticulum (ER) of tobacco protoplasts, they become substrates for ER ...
Richard S. Marshall +69 more
core +1 more source
Toxins, 2018 Ricin, a highly lethal toxin derived from the seeds of Ricinus communis (castor beans) is considered a potential biological threat agent due to its high availability, ease of production, and to the lack of any approved medical countermeasure against ...
Reut Falach +11 more
doaj +1 more source
How are proteins reduced in the endoplasmic reticulum? [PDF]
, 2018 The reversal of thiol oxidation in proteins within the endoplasmic reticulum (ER) is crucial for protein folding, degradation, chaperone function, and the ER stress response. Our understanding of this process is generally poor but progress has been made.
Bulleid, Neil +2 more
core +2 more sources
Immunochromatography Detection of Ricin in Environmental and Biological Samples
Nano Biomedicine and Engineering, 2011 Ricin has been considered as a potential agent of biological warfare or terrorist attack. This work is aimed to develop and evaluate a rapid test strip for the assay of ricin in environmental and biological samples.
Junhua Wu +7 more
doaj +1 more source
The distribution of lectins across the phylum Nematoda : a genome-wide search [PDF]
, 2017 Nematodes are a very diverse phylum that has adapted to nearly every ecosystem. They have developed specialized lifestyles, dividing the phylum into free-living, animal, and plant parasitic species. Their sheer abundance in numbers and presence in nearly
Bauters, Lander +2 more
core +6 more sources
Methods for nanoparticle labeling of ricin and effect on toxicity [PDF]
, 2009 The unique optical properties associated with nanostructured materials that support the excitation of surface plasmons offer many new opportunities for the enhanced optical investigation of biological materials that pose a security threat. In particular,
Graham, Duncan +4 more
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Post-Exposure Anti-Ricin Treatment Protects Swine against Lethal Systemic and Pulmonary Exposures
Toxins, 2020 Ricin, a plant-derived toxin originating from the seeds of Ricinus communis (castor bean plant), is one of the most lethal toxins known. To date, there is no approved post-exposure therapy for ricin exposures.
Reut Falach +14 more
doaj +1 more source
Differential neutralizing activities of a single domain camelid antibody (VHH) specific for ricin toxin's binding subunit (RTB). [PDF]
PLoS ONE, 2014 Ricin, a member of the A-B family of ribosome-inactivating proteins, is classified as a Select Toxin by the Centers for Disease Control and Prevention because of its potential use as a biothreat agent.
Cristina Herrera +4 more
doaj +1 more source
Reversibility of cell surface label rearrangement [PDF]
, 1976 Cell surface labeling can cause rearrangements of randomly distributed membrane components. Removal of the label bound to the cell surface allows the membrane components to return to their original random distribution, demonstrating that label is ...
Brown, Susan Smith, Revel, Jean-Paul
core +1 more source