Results 41 to 50 of about 11,992 (210)
Differential neutralizing activities of a single domain camelid antibody (VHH) specific for ricin toxin's binding subunit (RTB). [PDF]
PLoS ONE, 2014 Ricin, a member of the A-B family of ribosome-inactivating proteins, is classified as a Select Toxin by the Centers for Disease Control and Prevention because of its potential use as a biothreat agent.
Cristina Herrera +4 more
doaj +1 more source
Journal of Applied Toxicology, Volume 46, Issue 11, Page 3973-3988, November 2026.ABSTRACT Moringa oleifera Lam. seeds contain WSMoL, a lectin previously studied for toxicity and pharmacological effects. In this study, we investigated WSMoL (10, 25, or 50 mg/kg i.p.) for acute and 14‐day repeated‐dose toxicity, as well as genotoxicity, in Swiss mice.
Alícia Natalie Silva dos Santos +10 more
wiley +1 more source
A case of accidental Ricin poisoning [PDF]
, 2004 A case report of accidental, mild ricin poisoning by ingestion of ten Castor beans by a 70 year old man. The clinical presentation is followed by a discussion about the toxicity of ricin, its use and misuse and the contrast between the toxicity of pure ...
Despott, Edward, Cachia, Mario J.
core
Rare Metals, Volume 45, Issue 11, November 2026.ABSTRACT Defect engineering plays a crucial role in regulating the active sites and reaction pathways of nanozymes. In this work, oxygen vacancies (Vo) were successfully introduced and stably regulated in ternary CoFeMo layered double hydroxide (CFM LDHs) via a microwave‐assisted hydrothermal strategy, leading to the construction of oxygen‐vacancy‐rich
Min An +8 more
wiley +1 more source
ISOLATION OF CRYSTALLINE RICIN [PDF]
Journal of General Physiology, 1948 A toxic crystalline protein has been isolated from crude extracts of castor bean meal. Ultracentrifuge and electrophoresis tests show the crystalline protein to become fairly homogeneous after three or four crystallizations. This is also confirmed by toxicity measurements.
M, KUNITZ, M R, McDONALD
openaire +2 more sources
ToxinsRicin is a highly potent toxin that has been used in various attempts at bioterrorism worldwide. Although a vaccine for preventing ricin poisoning (RiVax™) is in clinical development, there are currently no commercially available prophylaxis or ...
Loïs Lequesne +11 more
doaj +1 more source
Advanced Science, Volume 13, Issue 55, 5 October 2026.Aberrant GALNT7‐mediated O‐GalNAcylation stabilizes TAZ to drive gallbladder cancer progression through a feed‐forward transcriptional loop. Structure‐based screening identifies Olaparib as a potent GALNT7 antagonist that disrupts this oncogenic axis, providing an immediate therapeutic strategy for this aggressive malignancy.
Peng Qiu +11 more
wiley +1 more source
Acta Scientiarum. Agronomy, 2011 In this study, we developed a bioassay to quantify the ricin toxin content of castor bean seeds. Existing quantification methods do not always reflect actual toxicity of the seeds analyzed, which may present lower ricin content even though they are more ...
Carlos Alberto Rauer Demant +2 more
doaj +1 more source
AVIDbase: A biologically accurate structural dataset of nanobody‐antigen complexes
Protein Science, Volume 35, Issue 9, September 2026.Abstract Accurate structural data in a standardized format is one of the key factors behind the success of machine learning (ML)‐based methods for protein design and structure prediction. However, their application to nanobody‐antigen complexes has lower success rates compared to globular protein complexes, partly due to the limited amount of high ...
Tadej Medved +3 more
wiley +1 more source
Ricin-JJX12 complexes are endocytosed via a macropinocytosis-like mechanism.
, 2016 A549 cells were treated with (panels A-C) 100 μM dynasore, (panels D-F) 0.6 μM LatA or (panels G-I) 200 μM EIPA, as described in the Materials and Methods. The cells were then treated with ricin-FITC, ricin-FITC with JJX12 or ricin-FITC with JNA6.
Cristina Herrera (576490) +4 more
core +1 more source