Results 41 to 50 of about 10,488 (210)
Post-Exposure Anti-Ricin Treatment Protects Swine against Lethal Systemic and Pulmonary Exposures
Toxins, 2020 Ricin, a plant-derived toxin originating from the seeds of Ricinus communis (castor bean plant), is one of the most lethal toxins known. To date, there is no approved post-exposure therapy for ricin exposures.
Reut Falach +14 more
doaj +1 more source
Differential neutralizing activities of a single domain camelid antibody (VHH) specific for ricin toxin's binding subunit (RTB). [PDF]
PLoS ONE, 2014 Ricin, a member of the A-B family of ribosome-inactivating proteins, is classified as a Select Toxin by the Centers for Disease Control and Prevention because of its potential use as a biothreat agent.
Cristina Herrera +4 more
doaj +1 more source
Detection of Ricin Contamination in Ground Beef by Electrochemiluminescence Immunosorbent Assay
Toxins, 2011 Ricin is a highly toxic protein present in the seeds of Ricinus communis (castor), grown principally as a source of high quality industrial lubricant and as an ornamental.
David L. Brandon
doaj +1 more source
Journal of Applied Toxicology, EarlyView.ABSTRACT Moringa oleifera Lam. seeds contain WSMoL, a lectin previously studied for toxicity and pharmacological effects. In this study, we investigated WSMoL (10, 25, or 50 mg/kg i.p.) for acute and 14‐day repeated‐dose toxicity, as well as genotoxicity, in Swiss mice.
Alícia Natalie Silva dos Santos +10 more
wiley +1 more source
, 2014 `Ricin Toxin’ brings together a collection of in depth and cutting edge reviews that focus on the current understanding of ricin toxins. This e-book provides a historical background, innovations in detection, identification and medical countermeasures ...
core +1 more source
ISOLATION OF CRYSTALLINE RICIN [PDF]
Journal of General Physiology, 1948 A toxic crystalline protein has been isolated from crude extracts of castor bean meal. Ultracentrifuge and electrophoresis tests show the crystalline protein to become fairly homogeneous after three or four crystallizations. This is also confirmed by toxicity measurements.
M, KUNITZ, M R, McDONALD
openaire +2 more sources
Advanced Science, Volume 13, Issue 32, 9 June 2026.Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang +7 more
wiley +1 more source
A case of accidental Ricin poisoning [PDF]
, 2004 A case report of accidental, mild ricin poisoning by ingestion of ten Castor beans by a 70 year old man. The clinical presentation is followed by a discussion about the toxicity of ricin, its use and misuse and the contrast between the toxicity of pure ...
Despott, Edward, Cachia, Mario J.
core
eFood, Volume 7, Issue 3, June 2026.Edulitin 2 is a ribotoxin‐like protein exhibiting a potent antiproliferative activity towards Caco‐2 and HT29 cells by programmed cell death. However, edulitin 2 does not affect gut microbiota growth, despite damaging fungal ribosomes. ABSTRACT Porcini (Boletus edulis Bull.) are a reservoir of pharmacological biomolecules with health‐promoting ...
Massimo Bortolotti +11 more
wiley +1 more source
Ricin-JJX12 complexes are endocytosed via a macropinocytosis-like mechanism.
, 2016 A549 cells were treated with (panels A-C) 100 μM dynasore, (panels D-F) 0.6 μM LatA or (panels G-I) 200 μM EIPA, as described in the Materials and Methods. The cells were then treated with ricin-FITC, ricin-FITC with JJX12 or ricin-FITC with JNA6.
Cristina Herrera (576490) +4 more
core +1 more source