Results 51 to 60 of about 11,668 (212)
Functional Specialization of Clathrin‐Independent Endocytic Routes: Mechanisms and Cellular Roles
Distinct clathrin‐independent endocytic (CIE) routes support specialized cellular functions across different contexts. Created with Biorender.com. ABSTRACT Clathrin‐independent endocytosis (CIE) comprises a diverse repertoire of internalization mechanisms that operate in parallel with clathrin‐mediated endocytosis.
Andrea Francesco Benvenuto +5 more
wiley +1 more source
Cytosolic entry of Shiga-like toxin A chain from the yeast endoplasmic reticulum requires catalytically active Hrd1p [PDF]
Background Escherichia coli Shiga-like toxin 1 normally traffics to the endoplasmic reticulum (ER) in sensitive mammalian cells from where the catalytic A chain (SLTxA1) dislocates to the cytosol to inactivate ribosomes.
Lynne M. Roberts (150050) +21 more
core +2 more sources
Deep Mutational Scanning for the Study and Engineering of Protein Assemblies
This review explores how deep mutational scanning (DMS) can be used to improve understanding and accelerate engineering of protein assemblies, from natural fibers to engineered nanocages. We discuss various types of protein assemblies and their characterization, provide an introduction to the DMS technique, and then highlight examples in which DMS has ...
Jenna B. Wolfanger +2 more
wiley +1 more source
`Ricin Toxin’ brings together a collection of in depth and cutting edge reviews that focus on the current understanding of ricin toxins. This e-book provides a historical background, innovations in detection, identification and medical countermeasures ...
core +1 more source
Year‐round spawning increases throughput of genetic modification of common carp (Cyprinus carpio)
Abstract The common carp (Cyprinus carpio) is an economically and ecologically significant species. It is both one of the most highly produced fish in aquaculture globally and a persistent, widespread invasive species. Research efforts focused on understanding its biology, improving traits for aquaculture, and generating next‐generation carp control ...
Julie Badger +12 more
wiley +1 more source
Recommended Immunological Assays to Screen for Ricin-Containing Samples
Ricin, a toxin from the plant Ricinus communis, is one of the most toxic biological agents known. Due to its availability, toxicity, ease of production and absence of curative treatments, ricin has been classified by the Centers for Disease Control and ...
Stéphanie Simon +8 more
doaj +1 more source
Ricin-JJX12 complexes are endocytosed via a macropinocytosis-like mechanism.
A549 cells were treated with (panels A-C) 100 μM dynasore, (panels D-F) 0.6 μM LatA or (panels G-I) 200 μM EIPA, as described in the Materials and Methods. The cells were then treated with ricin-FITC, ricin-FITC with JJX12 or ricin-FITC with JNA6.
Cristina Herrera (576490) +4 more
core +1 more source
Neutralising antibodies against ricin toxin. [PDF]
The Centers for Disease Control and Prevention have listed the potential bioweapon ricin as a Category B Agent. Ricin is a so-called A/B toxin produced by plants and is one of the deadliest molecules known. It is easy to prepare and no curative treatment
Julie Prigent +8 more
doaj +1 more source
ABSTRACT Silver‐doped cerium oxide nanoparticles (Ag/CeO2 NPs) were synthesized using Ricinus communis seed extract as a bio‐derived fuel in a solution combustion method. The combustion reaction, carried out at 450°C with AgNO3 and (NH4)2[Ce (NO3)6] as metal precursors, produced CeO2 and Ag/CeO2 NPs.
T. N. Ravishankar +5 more
wiley +1 more source
Ricin is a type II ribosome-inactivating toxin that catalytically inactivates ribosomes ultimately leading to cell death. The toxicity of ricin along with the prevalence of castor beans (its natural source) has led to its increased notoriety and ...
Sarah J. C. Whitfield +8 more
doaj +1 more source

